Zobrazeno 1 - 10
of 1 111 560
pro vyhledávání: '"0301 basic medicine"'
Autor:
Teena Mohan, Larisa V. Gubareva
Publikováno v:
Cold Spring Harbor perspectives in medicine. 12(1)
The neuraminidase (NA) of influenza A and B viruses plays a distinct role in viral replication and has a highly conserved catalytic site. Numerous sialic (neuraminic) acid analogs that competitively bind to the NA active site and potently inhibit enz
Autor:
Lucia C. Strader, Nicholas Morffy
Publikováno v:
Cold Spring Harbor perspectives in biology. 14(1)
Auxin signaling regulates growth and developmental processes in plants. The core of nuclear auxin signaling relies on just three components: TIR1/AFBs, Aux/IAAs, and ARFs. Each component is itself made up of several domains, all of which contribute t
Autor:
Gurpreet Singh Bhalla, Kundan Tandel, Kavita Sahai, R.M. Gupta, Pooja Mahajan, S.P.S. Shergill, Vijaya Swarnim, Mahadevan Kumar
Publikováno v:
Medical Journal Armed Forces India. 79:267-274
Background Carbapenemase producing gram-negative bacteria (GNB) has become a huge problem in majority of tertiary care centers worldwide. They are associated with very high morbidity and mortality rates, especially when they cause invasive infections
Autor:
Philipp Westhoff, Dominik Brilhaus, David Stucki, Andreas P.M. Weber, Peter Brenneisen, Wilhelm Stahl
Publikováno v:
International Journal for Vitamin and Nutrition Research. 93:122-131
Abstract: Carbon monoxide (CO) is endogenously produced upon degradation of heme by heme oxygenases (HOs) and is suggested to act as a gaseous signaling molecule. The expression of HO-1 is triggered by the Nrf2-Keap1 signaling pathway which responds
Publikováno v:
Int J Vitam Nutr Res
Abstract: Lipoprotein(a)(Lp[a]) is a low-density lipoprotein-cholesterol (LDL-C)-like particle with potent pro-atherothrombotic properties. The association of Lp(a) with several circulating factors, including vitamins, remains unresolved. We performe
Publikováno v:
Cancer Biotherapy and Radiopharmaceuticals. 38:132-139
Background: The procancer effect of TEA domain transcription factor 4 (TEAD4) has been gradually discovered. However, its expression in esophageal cancer (EC) cells and its effect on proliferation ...
Autor:
Rustom Antia, Christiane S Eberhardt, Ali H. Ellebedy, Susanne L. Linderman, Veronika I. Zarnitsyna, Rafi Ahmed, Carl W. Davis
Publikováno v:
Cold Spring Harbor perspectives in medicine. 11(11)
Although we develop influenza immunity from an early age, it is insufficient to prevent future infection with antigenically novel strains. One proposed way to generate long-term protective immunity against a broad range of influenza virus strains is
Autor:
Heather Elphick, Kevin W Southern
Publikováno v:
The Cochrane Library
Background Allergic bronchopulmonary aspergillosis (ABPA) is an allergic reaction to colonisation of the lungs with the fungus Aspergillus fumigatus and affects around 10% of people with cystic fibrosis. ABPA is associated with an accelerated decline
Publikováno v:
International Journal for Vitamin and Nutrition Research. 93:42-53
Abstract. Carotenoid intake is associated with low mortality and cancer risks; data on non-provitamin carotenoid intake is limited especially in Asians. We aimed to estimate carotenoid intake in Japanese adult women. Carotenoid content database compr
Publikováno v:
International Journal for Vitamin and Nutrition Research. 93:9-17
Abstract. Chronic, systemic inflammation, which is associated with obesity and numerous other diseases, impairs iron status by increasing hepcidin concentration. Inflammation also decreases the concentration of transferrin, the main iron transport pr