Zobrazeno 1 - 10
of 600
pro vyhledávání: '"35"'
Autor:
Kopycinski, Jakub1 j.kopycinski@imperial.ac.uk, Hayes, Peter1, Ashraf, Ambreen1, Cheeseman, Hannah1, Lala, Francesco1, Czyzewska-Khan, Justyna1, Spentzou, Aggeliki1, Gill, Dilbinder K.1, Keefer, Michael C.2, Excler, Jean-Louis3, Fast, Patricia3, Cox, Josephine1, Gilmour, Jill1
Publikováno v:
PLoS ONE. Mar2014, Vol. 9 Issue 3, p1-10. 10p.
Autor:
Angelique A. C. Lemckert, Jos M. Grimbergen, Irma Damen, Marco G. Cecchini, Germaine Penders, Niels Helmus, David Zuijdgeest, Michelle van Meerendonk, Wouter Koudstaal, Olga J.A.E Ophorst, Abraham Bout, Richard van Rijnsoever, Jaap Goudsmit, Antoinette Wetterwald, Björn F. Koel, Eric Hartkoorn, Marie-Pierre de Béthune, Ronald Vogels, Stefan Kostense, Laura Panitti, Mieke Caroline Sprangers, Menzo J. E. Havenga, Paul H.A. Quax
Publikováno v:
Journal of virology, 77(15), 8263-8271. American Society for Microbiology
Journal of Virology, 15, 77, 8263-8271
Journal of Virology, 15, 77, 8263-8271
Replication-deficient human adenovirus type 5 (Ad5) can be produced to high titers in complementing cell lines, such as PER.C6, and is widely used as a vaccine and gene therapy vector. However, preexisting immunity against Ad5 hampers consistency of
Autor:
Pengju Li, Xiangrui Li, Yuanyuan Liang, Yuhua Li, Zhenchao Zhang, Xiaoxu Nan, Qingqing Liu, Gaigai Hong, Qing Xie, Shuai Wang
Publikováno v:
Veterinary parasitology. 260
Toxoplasma gondii rhoptry proteins (TgROPs) have been considered the main targets and indicator molecules for immune diagnosis and prophylaxis because they present during the initial process of invasion. The aim of this study was to evaluate the prot
Autor:
K-Q Xin, N Jounai, K Someya, K Honma, H Mizuguchi, S Naganawa, K Kitamura, T Hayakawa, S Saha, F Takeshita, K Okuda, M Honda, D M Klinman
Publikováno v:
Gene Therapy. 12:1769-1777
Immunization involving a DNA vaccine prime followed by an adenovirus type 5 (Ad5) boost elicited a protective immune response against SHIV challenge in monkeys. However, the hepatocellular tropism of Ad5 limits the safety of this viral vector. This s
Autor:
Jill Gilmour, Dilbinder K. Gill, Hannah Cheeseman, Josephine H. Cox, Peter Hayes, Justyna Czyzewska-Khan, Aggeliki Spentzou, Jean-Louis Excler, Jakub Kopycinski, Michael C. Keefer, Ambreen Ashraf, Francesco Lala, Patricia E. Fast
Publikováno v:
PLoS ONE
PLoS ONE, Vol 9, Iss 3, p e90378 (2014)
PLoS ONE, Vol 9, Iss 3, p e90378 (2014)
A correlation between in vivo and in vitro virus control mediated by CD8+ T-cell populations has been demonstrated by CD8 T-cell-mediated inhibition of HIV-1 and SIV replication in vitro in peripheral blood mononuclear cells (PBMCs) from infected hum
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::948f7fc7b925ebeadace08b6d1cfefab
http://hdl.handle.net/10044/1/87009
http://hdl.handle.net/10044/1/87009
Adenovirus (Ad) vaccine vectors have proven highly immunogenic in multiple experimental models, but the innate immune responses induced by these vectors remain poorly characterized. Here we report innate cytokine responses to 5 different Ad vectors i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::efe340cd2811b9dc80e7a2bcb70fd4f7
https://europepmc.org/articles/PMC3446581/
https://europepmc.org/articles/PMC3446581/
Autor:
Wouter Koudstaal, Ben Berkhout, Margreet Bakker, Niels Helmus, Ronald Vogels, Stefan Kostense, Mieke Caroline Sprangers, Menzo J. E. Havenga, Jaap Goudsmit, Gerrit Jan Weverling, Germaine Penders
Publikováno v:
AIDS (London, England), 18(8), 1213-1216. Lippincott Williams and Wilkins
The seroprevalence of adenovirus types 5 (Ad5) and 35 (Ad35) was investigated in patients at risk of AIDS. The seroprevalence of Ad5 was higher than Ad35 in HIV-infected patients from the Netherlands (60% versus 7%) and sub-Saharan Africa (90% versus
Autor:
Gert Gillissen, Marjolein van der Meer, Katarina Radosevic, Jaap Goudsmit, Ariane Rodriguez, Rie von Eyben, Maria Grazia Pau, Carolien Warnar, Angelique A. C. Lemckert
Publikováno v:
Clinical and vaccine immunology, 17(11), 1687-1694. American Society for Microbiology
The most advanced malaria vaccine, RTS,S, is comprised of an adjuvant portion of the Plasmodium falciparum circumsporozoite (CS) protein fused to and admixed with the hepatitis B virus surface antigen. This vaccine confers short-term protection again
Autor:
Kristen Syvertsen, Devika Zachariah, Jill Gilmour, Frances Priddy, Patricia E. Fast, Juliet Mpendo, K. Anas, Emmanuel Cormier, François Roman, Burc Barin, Jim Ackland, William Kilembe, Josephine H. Cox, Peter Hayes, Elwyn Chomba, Gerald Voss, Angela Lombardo, Eugene Ruzagira, Lorna Clark, Gloria Omosa-Manyonyi, Eddy Sayeed, Dagna Laufer, Marguerite Koutsoukos, Len Dally, Patricia Bourguignon, Gwynn Stevens, Alix Collard
Publikováno v:
e0125954
PLoS ONE
PLoS ONE, Vol 10, Iss 5, p e0125954 (2015)
PLoS ONE
PLoS ONE, Vol 10, Iss 5, p e0125954 (2015)
Background Sequential prime-boost or co-administration of HIV vaccine candidates based on an adjuvanted clade B p24, RT, Nef, p17 fusion protein (F4/AS01) plus a non-replicating adenovirus 35 expressing clade A Gag, RT, Int and Nef (Ad35-GRIN) may le
Autor:
Papa Toure, Anuj Gaggar, Robert Strauss, Branka Horvat, Nancy B. Kiviat, Shaoheng Ni, Nelson DiPaolo, Daniel Stone, Salif Sow, Zong Yi Li, Sebastian Tuve, Dmitry M. Shayakhmetov, André Lieber
In contrast to commonly used serotype 5-based adenovirus (Ad) vectors, Ad's containing fibers derived from B-group serotype 35 (Ad5/35) efficiently transduce human DCs ex vivo and appear to target antigen-presenting cells after intravenous injection
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::25a442e57021f54a58456c4fd03786c6
https://europepmc.org/articles/PMC1424671/
https://europepmc.org/articles/PMC1424671/