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pro vyhledávání: '"Haydn T. Kissick"'
Autor:
Weiwen Zhang, Anna B. Morris, Erica V. Peek, Geeta Karadkhele, Jennifer M. Robertson, Haydn T. Kissick, Christian P. Larsen
Publikováno v:
Frontiers in Immunology
Frontiers in Immunology, Vol 12 (2021)
Frontiers in Immunology, Vol 12 (2021)
Cytomegalovirus (CMV) is one of the most commonly recognized opportunistic pathogens and remains the most influential known parameter in shaping an individual’s immune system. As such, T cells induced by CMV infection could have a long-term impact
Publikováno v:
Int Immunol
Tumor-infiltrating CD8 T cells are associated with improved patient survival and response to immunotherapy in various cancers. Persistent antigen leads to CD8 T-cell exhaustion, where proliferation/self-renewal and killing are divided within distinct
Publikováno v:
Cold Spring Harbor Perspectives in Biology. 14:a037804
The pool of memory CD8 T cells is comprised of highly specialized subpopulations of cells with both shared and distinct functions. The ongoing study of T-cell memory is focused on how these different subpopulations arise, how the cells are maintained
Autor:
Haydn T. Kissick, Anil Verma, Rakesh Lodha, Haroon Kalam, Kulkanya Chokephaibulkit, Nattawat Onlamoon, Anmol Chandele, Dhiraj Kumar, Harekrushna Panda, Jaturong Sewatanon, Sivaram Gunisetty, Siyu Wang, Guruprasad R. Medigeshi, Elluri Seetharami Reddy, Kaustuv Nayak, Rafi Ahmed, Sushil K. Kabra, Kaja Murali-Krishna, Nasikarn Angkasekwinai, Rama Akondy, Mohit Singla, Kovit Pattanapanyasat
Publikováno v:
Journal of Virology
Epidemiological studies suggest that India has the largest number of dengue virus infection cases worldwide. However, there is minimal information about the immunological responses in these patients. CD8 T cells are important in dengue, because they
Autor:
Rafi Ahmed, William H. Hudson, Donald J. McGuire, Nataliya Prokhnevska, Julia Gensheimer, Rama Akondy, Haydn T. Kissick
Publikováno v:
Nature Communications
Nature Communications, Vol 10, Iss 1, Pp 1-11 (2019)
Nature Communications, Vol 10, Iss 1, Pp 1-11 (2019)
In response to viral infection, CD8+ T cells undergo expansion and differentiate into distinct classes of effector cells. After clearance of the virus, a small population of long-lived memory cells persists. Comprehensive studies have defined the pro
Autor:
Hai-Hui Xue, Haydn T. Kissick, Se Jin Im, Arlene H. Sharpe, Gordon J. Freeman, Helder I. Nakaya, Rafi Ahmed, Qiang Shan, J. Scott Hale, Michael Y. Gerner, Tahseen H. Nasti, Ronald N. Germain, Matheus Carvalho Bürger, Judong Lee, Masao Hashimoto, Junghwa Lee
Publikováno v:
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
Universidade de São Paulo (USP)
instacron:USP
Chronic viral infections are characterized by a state of CD8+ T-cell dysfunction that is associated with expression of the programmed cell death 1 (PD-1) inhibitory receptor. A better understanding of the mechanisms that regulate CD8+ T-cell response