Zobrazeno 1 - 10
of 35
pro vyhledávání: '"Christie M. Ballantyne"'
Autor:
Martina Müller-Nurasyid, Jerome I. Rotter, David M. Evans, John P. Kemp, Emelia J. Benjamin, Graciela E. Delgado, Vilmundur Gudnason, Ann Hammarstedt, Panos Deloukas, Aroon D. Hingorani, Riccardo E. Marioni, David Stacey, Jenny van Dongen, Eric Boerwinkle, Joachim Heinrich, Yongmei Liu, S. Goya Wannamethee, Delilah Zabaneh, Braxton D. Mitchell, Marie Standl, Jackie F. Price, Maria G. Stathopoulou, Yoav Ben-Shlomo, Joris Deelen, Eero Kajantie, Mohammadreza Abdollahi, Christie M. Ballantyne, Johan G. Eriksson, Ilkka Seppälä, Elnaz Naderi, Barbara J. Jefferis, Richard W Morris, Nicholas J. Timpson, George Dedoussis, Sirpa Jalkanen, Mika Kivimäki, Perminder S. Sachdev, Diana van Heemst, Melanie Waldenberger, Gaurav Singhal, Elisabeth Thiering, Olli T. Raitakari, Anders Hamsten, Zoltán Kutalik, L. Bain, Eco J. C. de Geus, Tarunveer S. Ahluwalia, Yuri Milaneschi, Hubert Scharnagl, Juan P. Casas, Georg Homuth, Claes Ohlsson, Abbas Dehghan, Nicola J. Armstrong, Behrooz Z. Alizadeh, Terho Lehtimäki, Steve E. Humphries, Naveed Sattar, Bram P. Prins, Peter Rossing, Sophie Visvikis-Siest, Joana A. Revez, Ilja M. Nolte, Stella Trompet, Harold Snieder, Marian Beekman, Diana Marek, Beate St Pourcain, Thorkild I. A. Sørensen, Silvia Naitza, Karen A. Mather, Uwe Völker, Eline Slagboom, Tina Shah, Magdalene C. Jawahar, Jens Baumert, Alexander Teumer, Dorret I. Boomsma, Marcus E. Kleber, Peter Vollenweider, Wolfgang Koenig, Brenda W.J.H. Penninx, Kenneth Rice, Ian J. Deary, Pedro Marques-Vidal, Donna K. Arnett, Eleonora Porcu, Jouke-Jan Hottenga, Maria Sabater-Lleal, Bruce M. Psaty, Matthias Nauck, Dan Mellström, Joel Eriksson, Bernhard T. Baune, Debbie A Lawlor, Catherine Toben, Peter H. Whincup, Toshiko Tanaka, Stavroula Kanoni, Katri Räikkönen, Gonneke Willemsen, Bengt Sennblad, Julian N. Trollor, Yalda Jamshidi, Sarah E. Harris, Jari Lahti, Joshua C. Bis, Peter Durda, Yen Pei C. Chang, Jorgen Engmann, Tom R. Gaunt, Stella Aslibekyan, Anbupalam Thalamuthu, Mary F. Feitosa, Angela Silveira, Tine Jess, Stela McLachlan, J. Wouter Jukema, Chen Lu, Simon P. Mooijaart, Tim D. Spector, Harald Grallert, Winfried März, Alexandros M. Petrelis, Manuel A. R. Ferreira, Meena Kumari
Publikováno v:
Human molecular genetics, 30(5), 393-409. Oxford University Press
Human Molecular Genetics, 30(5), 393-409. OXFORD UNIV PRESS
Human Molecular Genetics
Ahluwalia, T S, De Geus, E, Milaneschi, Y, Hottenga, J-J, Van Dongen, J, Willemsen, G, Boomsma, D I, Alizadeh, B Z & CHARGE Inflammation Working Group 2021, ' Genome-Wide Association Study of Circulating Interleukin 6 Levels Identifies Novel Loci ', Human molecular genetics, vol. 30, no. 5, pp. 393-409 . https://doi.org/10.1093/hmg/ddab023
Hum Mol Genet
Human Molecular Genetics, 30(5), 393-409. Oxford University Press
Human molecular genetics, vol. 30, no. 5, pp. 393-409
CHARGE Inflammation working group 2021, ' Genome-wide association study of circulating interleukin 6 levels identifies novel loci ', Human Molecular Genetics, vol. 30, no. 5, pp. 393-409 . https://doi.org/10.1093/hmg/ddab023
Human Molecular Genetics, Oxford University Press (OUP), 2021, ⟨10.1093/hmg/ddab023⟩
Hum. Mol. Genet. 30, 393-409 (2021)
Ahluwalia, T S, Prins, B P, Abdollahi, M, Armstrong, N J, Aslibekyan, S, Bain, L, Jefferis, B, Baumert, J, Beekman, M, Ben-shlomo, Y, Bis, J C, Mitchell, B D, De Geus, E, Delgado, G E, Marek, D, Eriksson, J, Kajantie, E, Kanoni, S, Kemp, J P, Lu, C, Marioni, R E, Mclachlan, S, Milaneschi, Y, Nolte, I M, Petrelis, A M, Porcu, E, Sabater-lleal, M, Naderi, E, Seppälä, I, Shah, T, Singhal, G, Standl, M, Teumer, A, Thalamuthu, A, Thiering, E, Trompet, S, Ballantyne, C M, Benjamin, E J, Casas, J P, Toben, C, Dedoussis, G, Deelen, J, Durda, P, Engmann, J, Feitosa, M F, Grallert, H, Hammarstedt, A, Harris, S E, Homuth, G, Hottenga, J, Jalkanen, S, Jamshidi, Y, Jawahar, M C, Jess, T, Kivimaki, M, Kleber, M E, Lahti, J, Liu, Y, Marques-vidal, P, Mellström, D, Mooijaart, S P, Müller-nurasyid, M, Penninx, B, Revez, J A, Rossing, P, Räikkönen, K, Sattar, N, Scharnagl, H, Sennblad, B, Silveira, A, Pourcain, B S, Timpson, N J, Trollor, J, Van Dongen, J, Van Heemst, D, Visvikis-siest, S, Vollenweider, P, Völker, U, Waldenberger, M, Willemsen, G, Zabaneh, D, Morris, R W, Arnett, D K, Baune, B T, Boomsma, D I, Chang, Y C, Deary, I J, Deloukas, P, Eriksson, J G, Evans, D M, Ferreira, M A, Gaunt, T, Gudnason, V, Hamsten, A, Heinrich, J, Hingorani, A, Humphries, S E, Jukema, J W, Koeing, W, Kumari, M, Kutalik, Z, Lawlor, D A, Lehtimäki, T, März, W, Mather, K, Naitza, S, Nauck, M, Ohlsson, C, Price, J F, Raitakari, O, Rice, K, Sachdev, P S, Slagboom, E, Sørensen, T I A, Spector, T, Stacey, D, Stathopoulou, M G, Tanaka, T, Wannamethee, S G, Whincup, P, Rotter, J I, Dehghan, A, Boerwinkle, E, Psaty, B M, Snieder, H & Alizadeh, B Z 2021, ' Genome-wide association study of circulating Interleukin 6 levels identifies novel loci ', Human Molecular Genetics . https://doi.org/10.1093/hmg/ddab023
European Journal of Human Genetics, 28(SUPPL 1), 307-308. Nature Publishing Group
Ahluwalia, T S, Prins, B P, Abdollahi, M, Armstrong, N J, Aslibekyan, S, Bain, L, Jefferis, B, Baumert, J, Beekman, M, Ben-Shlomo, Y, Bis, J C, Mitchell, B D, de Geus, E, Delgado, G E, Marek, D, Eriksson, J, Kajantie, E, Kanoni, S, Kemp, J P, Lu, C, Marioni, R E, McLachlan, S, Milaneschi, Y, Nolte, I M, Petrelis, A M, Porcu, E, Sabater-Lleal, M, Naderi, E, Seppälä, I, Shah, T, Singhal, G, Standl, M, Teumer, A, Thalamuthu, A, Thiering, E, Trompet, S, Ballantyne, C M, Benjamin, E J, Casas, J P, Toben, C, Dedoussis, G, Deelen, J, Durda, P, Engmann, J, Feitosa, M F, Grallert, H, Hammarstedt, A, Jess, T, Rossing, P, Sørensen, T I A & CHARGE Inflammation Working Group 2021, ' Genome-Wide Association Study of Circulating Interleukin 6 Levels Identifies Novel Loci ', Human Molecular Genetics, vol. 30, no. 5, pp. 393–409 . https://doi.org/10.1093/hmg/ddab023
Human Molecular Genetics, 30(5), 393-409. OXFORD UNIV PRESS
Human Molecular Genetics
Ahluwalia, T S, De Geus, E, Milaneschi, Y, Hottenga, J-J, Van Dongen, J, Willemsen, G, Boomsma, D I, Alizadeh, B Z & CHARGE Inflammation Working Group 2021, ' Genome-Wide Association Study of Circulating Interleukin 6 Levels Identifies Novel Loci ', Human molecular genetics, vol. 30, no. 5, pp. 393-409 . https://doi.org/10.1093/hmg/ddab023
Hum Mol Genet
Human Molecular Genetics, 30(5), 393-409. Oxford University Press
Human molecular genetics, vol. 30, no. 5, pp. 393-409
CHARGE Inflammation working group 2021, ' Genome-wide association study of circulating interleukin 6 levels identifies novel loci ', Human Molecular Genetics, vol. 30, no. 5, pp. 393-409 . https://doi.org/10.1093/hmg/ddab023
Human Molecular Genetics, Oxford University Press (OUP), 2021, ⟨10.1093/hmg/ddab023⟩
Hum. Mol. Genet. 30, 393-409 (2021)
Ahluwalia, T S, Prins, B P, Abdollahi, M, Armstrong, N J, Aslibekyan, S, Bain, L, Jefferis, B, Baumert, J, Beekman, M, Ben-shlomo, Y, Bis, J C, Mitchell, B D, De Geus, E, Delgado, G E, Marek, D, Eriksson, J, Kajantie, E, Kanoni, S, Kemp, J P, Lu, C, Marioni, R E, Mclachlan, S, Milaneschi, Y, Nolte, I M, Petrelis, A M, Porcu, E, Sabater-lleal, M, Naderi, E, Seppälä, I, Shah, T, Singhal, G, Standl, M, Teumer, A, Thalamuthu, A, Thiering, E, Trompet, S, Ballantyne, C M, Benjamin, E J, Casas, J P, Toben, C, Dedoussis, G, Deelen, J, Durda, P, Engmann, J, Feitosa, M F, Grallert, H, Hammarstedt, A, Harris, S E, Homuth, G, Hottenga, J, Jalkanen, S, Jamshidi, Y, Jawahar, M C, Jess, T, Kivimaki, M, Kleber, M E, Lahti, J, Liu, Y, Marques-vidal, P, Mellström, D, Mooijaart, S P, Müller-nurasyid, M, Penninx, B, Revez, J A, Rossing, P, Räikkönen, K, Sattar, N, Scharnagl, H, Sennblad, B, Silveira, A, Pourcain, B S, Timpson, N J, Trollor, J, Van Dongen, J, Van Heemst, D, Visvikis-siest, S, Vollenweider, P, Völker, U, Waldenberger, M, Willemsen, G, Zabaneh, D, Morris, R W, Arnett, D K, Baune, B T, Boomsma, D I, Chang, Y C, Deary, I J, Deloukas, P, Eriksson, J G, Evans, D M, Ferreira, M A, Gaunt, T, Gudnason, V, Hamsten, A, Heinrich, J, Hingorani, A, Humphries, S E, Jukema, J W, Koeing, W, Kumari, M, Kutalik, Z, Lawlor, D A, Lehtimäki, T, März, W, Mather, K, Naitza, S, Nauck, M, Ohlsson, C, Price, J F, Raitakari, O, Rice, K, Sachdev, P S, Slagboom, E, Sørensen, T I A, Spector, T, Stacey, D, Stathopoulou, M G, Tanaka, T, Wannamethee, S G, Whincup, P, Rotter, J I, Dehghan, A, Boerwinkle, E, Psaty, B M, Snieder, H & Alizadeh, B Z 2021, ' Genome-wide association study of circulating Interleukin 6 levels identifies novel loci ', Human Molecular Genetics . https://doi.org/10.1093/hmg/ddab023
European Journal of Human Genetics, 28(SUPPL 1), 307-308. Nature Publishing Group
Ahluwalia, T S, Prins, B P, Abdollahi, M, Armstrong, N J, Aslibekyan, S, Bain, L, Jefferis, B, Baumert, J, Beekman, M, Ben-Shlomo, Y, Bis, J C, Mitchell, B D, de Geus, E, Delgado, G E, Marek, D, Eriksson, J, Kajantie, E, Kanoni, S, Kemp, J P, Lu, C, Marioni, R E, McLachlan, S, Milaneschi, Y, Nolte, I M, Petrelis, A M, Porcu, E, Sabater-Lleal, M, Naderi, E, Seppälä, I, Shah, T, Singhal, G, Standl, M, Teumer, A, Thalamuthu, A, Thiering, E, Trompet, S, Ballantyne, C M, Benjamin, E J, Casas, J P, Toben, C, Dedoussis, G, Deelen, J, Durda, P, Engmann, J, Feitosa, M F, Grallert, H, Hammarstedt, A, Jess, T, Rossing, P, Sørensen, T I A & CHARGE Inflammation Working Group 2021, ' Genome-Wide Association Study of Circulating Interleukin 6 Levels Identifies Novel Loci ', Human Molecular Genetics, vol. 30, no. 5, pp. 393–409 . https://doi.org/10.1093/hmg/ddab023
Interleukin 6 (IL-6) is a multifunctional cytokine with both pro- and anti-inflammatory properties with a heritability estimate of up to 61%. The circulating levels of IL-6 in blood have been associated with an increased risk of complex disease patho
Autor:
Sina A. Gharib, Kenneth Rice, Donna K. Arnett, Tõnu Esko, Annemarie I. Luik, Niki Dimou, Dabeeru C. Rao, Pamela J. Schreiner, Melissa A. Richard, Reedik Mägi, Nicholette D. Palmer, Stefan Weiss, Han Chen, Solomon K. Musani, W. James Gauderman, Christian Gieger, Kari E. North, Salman M. Tajuddin, Diana van Heemst, Rainer Rauramaa, Stephen B. Kritchevsky, Henry Völzke, Minjung Kho, Michele K. Evans, Ruth J. F. Loos, Correa Adolfo, Pedro Marques-Vidal, Diane M. Becker, Claude Bouchard, José Haba-Rubio, Georg Homuth, Kurt Lohman, Nora Franceschini, Caizheng Yu, Peter Vollenweider, Ervin F. Fox, Thomas Meitinger, Karen Schwander, Heming Wang, Morris A. Swertz, Aldi T. Kraja, José Eduardo Krieger, Xiuqing Guo, Tangchun Wu, Raymond Noordam, Yongmei Liu, Michael R. Brown, Patrick C.N. Rensen, Annette Peters, Jingmin Liu, Tuomo Rankinen, Robert B. Wallance, Timo A. Lakka, Stephen S. Rich, Yun Ju Sung, Meian He, Till Roenneberg, Wanqing Wen, Dennis O. Mook-Kanamori, M. A. Province, Evangelos Evangelou, L. Adrienne Cupples, Maxime M Bos, Paul S. de Vries, Hans J. Grabe, Lisa R. Yanek, Jiwon Lee, Mario Sims, Bruce M. Psaty, Treva Rice, Tanika N. Kelly, Brenda W.J.H. Penninx, Brigitte Kühnel, Maria E. Graff, Alexandre C. Pereira, Daniel J. Gottlieb, Charles N. Rotimi, Lynne E. Wagenknecht, Ashley van der Spek, Lisa W. Martin, Jeffrey R. O'Connell, Changwei Li, James E. Hixson, Chuan Gao, Alisa K. Manning, Sharon L.R. Kardia, Stella Aslibekyan, Andres Metspalu, Sami Heikkinen, Maris Alver, Xiao-Ou Shu, Amy R. Bentley, Susan Redline, Konstantin Strauch, Tamara B. Harris, Yuri Milaneschi, L.F. Bielak, Marjan Ilkov, Myriam Fornage, Ilja M. Nolte, André G. Uitterlinden, Dina Vojinovic, Hugues Aschard, Paul Elliott, Kent D. Taylor, Najaf Amin, James M. Shikany, Yong-Bing Xiang, Jerome I. Rotter, Vilmundur Gudnason, Cornelia M. van Duijn, Ko Willems van Dijk, Andrea R. V. R. Horimoto, Jonathan Marten, Olli T. Raitakari, Vincent Laville, Pirjo Komulainen, Zhe Wang, Traci M. Bartz, Mary F. Feitosa, Mike A. Nalls, Eric Boerwinkle, Alanna C. Morrison, Melanie Waldenberger, Alexander P. Reiner, Christie M. Ballantyne, Wei Zheng, Raphael Heinzer, M. Arfan Ikram, Colleen M. Sitlani, Lisa de las Fuentes, Patricia B. Munroe, Patricia A. Peyser, Brian E. Cade, Tamar Sofer, Xiaofeng Zhu, Nienke R. Biermasz, Harold Snieder, Elise Lim, Tuomas O. Kilpeläinen, Ching-Ti Liu, Terho Lehtimäki, Thomas W. Winkler, Leo-Pekka Lyytikäinen, Gudny Eiriksdottir, Stephen Sidney, Alan B. Zonderman, Charles Kooperberg
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-13 (2019)
Nature Communications
Nature Communications, 2019, 10 (1), pp.5121. ⟨10.1038/s41467-019-12958-0⟩
Nature Communications, 10. NATURE PUBLISHING GROUP
Nature Communications, 10:5121. Nature Publishing Group
Nature Communications, 10(1):5121. Nature Publishing Group
Nature Communications, 10(1):5121. Nature Publishing Group UK
Noordam, R, Bos, M M, Wang, H, Winkler, T W, Bentley, A R, Kilpeläinen, T O, de Vries, P S, Sung, Y J, Schwander, K, Cade, B E, Manning, A, Aschard, H, Brown, M R, Chen, H, Franceschini, N, Musani, S K, Richard, M, Vojinovic, D, Aslibekyan, S, Bartz, T M, de las Fuentes, L, Feitosa, M, Horimoto, A R, Ilkov, M, Kho, M, Kraja, A, Li, C, Lim, E, Liu, Y, Mook-Kanamori, D O, Rankinen, T, Tajuddin, S M, van der Spek, A, Wang, Z, Marten, J, Laville, V, Alver, M, Evangelou, E, Graff, M E, He, M, Kühnel, B, Lyytikäinen, L P, Marques-Vidal, P, Nolte, I M, Palmer, N D, Rauramaa, R, Shu, X O, Snieder, H, Weiss, S & Penninx, B W J H 2019, ' Multi-ancestry sleep-by-SNP interaction analysis in 126,926 individuals reveals lipid loci stratified by sleep duration ', Nature Communications, vol. 10, no. 1, 5121 . https://doi.org/10.1038/s41467-019-12958-0
Nature Communications, Nature Publishing Group, 2019, 10 (1), pp.5121. ⟨10.1038/s41467-019-12958-0⟩
Noordam, R, Bos, M M, Wang, H, Winkler, T W, Bentley, A R, Kilpeläinen, T O, de Vries, P S, Sung, Y J, Schwander, K, Cade, B E, Manning, A, Aschard, H, Brown, M R, Chen, H, Franceschini, N, Musani, S K, Richard, M, Vojinovic, D, Aslibekyan, S, Bartz, T M, de Las Fuentes, L, Feitosa, M, Horimoto, A R, Ilkov, M, Kho, M, Kraja, A, Li, C, Lim, E, Liu, Y, Mook-Kanamori, D O, Rankinen, T, Tajuddin, S M, van der Spek, A, Wang, Z, Marten, J, Laville, V, Alver, M, Evangelou, E, Graff, M E, He, M, Kühnel, B, Lyytikäinen, L-P, Marques-Vidal, P, Nolte, I M, Palmer, N D, Rauramaa, R, Shu, X-O, Snieder, H, Weiss, S, Wen, W, Yanek, L R, Adolfo, C, Ballantyne, C, Bielak, L, Biermasz, N R, Boerwinkle, E, Dimou, N, Eiriksdottir, G, Gao, C, Gharib, S A, Gottlieb, D J, Haba-Rubio, J, Harris, T B, Heikkinen, S, Heinzer, R, Hixson, J E, Homuth, G, Ikram, M A, Komulainen, P, Krieger, J E, Lee, J, Liu, J, Lohman, K K, Luik, A I, Mägi, R, Martin, L W, Meitinger, T, Metspalu, A, Milaneschi, Y, Nalls, M A, O'Connell, J, Peters, A, Peyser, P, Raitakari, O T, Reiner, A P, Rensen, P C N, Rice, T K, Rich, S S, Roenneberg, T, Rotter, J I, Schreiner, P J, Shikany, J, Sidney, S S, Sims, M, Sitlani, C M, Sofer, T, Strauch, K, Swertz, M A, Taylor, K D, Uitterlinden, A G, van Duijn, C M, Völzke, H, Waldenberger, M, Wallance, R B, van Dijk, K W, Yu, C, Zonderman, A B, Becker, D M, Elliott, P, Esko, T, Gieger, C, Grabe, H J, Lakka, T A, Lehtimäki, T, North, K E, Penninx, B W J H, Vollenweider, P, Wagenknecht, L E, Wu, T, Xiang, Y-B, Zheng, W, Arnett, D K, Bouchard, C, Evans, M K, Gudnason, V, Kardia, S, Kelly, T N, Kritchevsky, S B, Loos, R J F, Pereira, A C, Province, M, Psaty, B M, Rotimi, C, Zhu, X, Amin, N, Cupples, L A, Fornage, M, Fox, E F, Guo, X, Gauderman, W J, Rice, K, Kooperberg, C, Munroe, P B, Liu, C-T, Morrison, A C, Rao, D C, van Heemst, D & Redline, S 2019, ' Multi-ancestry sleep-by-SNP interaction analysis in 126,926 individuals reveals lipid loci stratified by sleep duration ', Nature Communications, vol. 10, no. 1, 5121 . https://doi.org/10.1038/s41467-019-12958-0
Nature communications, vol. 10, no. 1, pp. 5121
Nature Communications
Nature Communications, 2019, 10 (1), pp.5121. ⟨10.1038/s41467-019-12958-0⟩
Nature Communications, 10. NATURE PUBLISHING GROUP
Nature Communications, 10:5121. Nature Publishing Group
Nature Communications, 10(1):5121. Nature Publishing Group
Nature Communications, 10(1):5121. Nature Publishing Group UK
Noordam, R, Bos, M M, Wang, H, Winkler, T W, Bentley, A R, Kilpeläinen, T O, de Vries, P S, Sung, Y J, Schwander, K, Cade, B E, Manning, A, Aschard, H, Brown, M R, Chen, H, Franceschini, N, Musani, S K, Richard, M, Vojinovic, D, Aslibekyan, S, Bartz, T M, de las Fuentes, L, Feitosa, M, Horimoto, A R, Ilkov, M, Kho, M, Kraja, A, Li, C, Lim, E, Liu, Y, Mook-Kanamori, D O, Rankinen, T, Tajuddin, S M, van der Spek, A, Wang, Z, Marten, J, Laville, V, Alver, M, Evangelou, E, Graff, M E, He, M, Kühnel, B, Lyytikäinen, L P, Marques-Vidal, P, Nolte, I M, Palmer, N D, Rauramaa, R, Shu, X O, Snieder, H, Weiss, S & Penninx, B W J H 2019, ' Multi-ancestry sleep-by-SNP interaction analysis in 126,926 individuals reveals lipid loci stratified by sleep duration ', Nature Communications, vol. 10, no. 1, 5121 . https://doi.org/10.1038/s41467-019-12958-0
Nature Communications, Nature Publishing Group, 2019, 10 (1), pp.5121. ⟨10.1038/s41467-019-12958-0⟩
Noordam, R, Bos, M M, Wang, H, Winkler, T W, Bentley, A R, Kilpeläinen, T O, de Vries, P S, Sung, Y J, Schwander, K, Cade, B E, Manning, A, Aschard, H, Brown, M R, Chen, H, Franceschini, N, Musani, S K, Richard, M, Vojinovic, D, Aslibekyan, S, Bartz, T M, de Las Fuentes, L, Feitosa, M, Horimoto, A R, Ilkov, M, Kho, M, Kraja, A, Li, C, Lim, E, Liu, Y, Mook-Kanamori, D O, Rankinen, T, Tajuddin, S M, van der Spek, A, Wang, Z, Marten, J, Laville, V, Alver, M, Evangelou, E, Graff, M E, He, M, Kühnel, B, Lyytikäinen, L-P, Marques-Vidal, P, Nolte, I M, Palmer, N D, Rauramaa, R, Shu, X-O, Snieder, H, Weiss, S, Wen, W, Yanek, L R, Adolfo, C, Ballantyne, C, Bielak, L, Biermasz, N R, Boerwinkle, E, Dimou, N, Eiriksdottir, G, Gao, C, Gharib, S A, Gottlieb, D J, Haba-Rubio, J, Harris, T B, Heikkinen, S, Heinzer, R, Hixson, J E, Homuth, G, Ikram, M A, Komulainen, P, Krieger, J E, Lee, J, Liu, J, Lohman, K K, Luik, A I, Mägi, R, Martin, L W, Meitinger, T, Metspalu, A, Milaneschi, Y, Nalls, M A, O'Connell, J, Peters, A, Peyser, P, Raitakari, O T, Reiner, A P, Rensen, P C N, Rice, T K, Rich, S S, Roenneberg, T, Rotter, J I, Schreiner, P J, Shikany, J, Sidney, S S, Sims, M, Sitlani, C M, Sofer, T, Strauch, K, Swertz, M A, Taylor, K D, Uitterlinden, A G, van Duijn, C M, Völzke, H, Waldenberger, M, Wallance, R B, van Dijk, K W, Yu, C, Zonderman, A B, Becker, D M, Elliott, P, Esko, T, Gieger, C, Grabe, H J, Lakka, T A, Lehtimäki, T, North, K E, Penninx, B W J H, Vollenweider, P, Wagenknecht, L E, Wu, T, Xiang, Y-B, Zheng, W, Arnett, D K, Bouchard, C, Evans, M K, Gudnason, V, Kardia, S, Kelly, T N, Kritchevsky, S B, Loos, R J F, Pereira, A C, Province, M, Psaty, B M, Rotimi, C, Zhu, X, Amin, N, Cupples, L A, Fornage, M, Fox, E F, Guo, X, Gauderman, W J, Rice, K, Kooperberg, C, Munroe, P B, Liu, C-T, Morrison, A C, Rao, D C, van Heemst, D & Redline, S 2019, ' Multi-ancestry sleep-by-SNP interaction analysis in 126,926 individuals reveals lipid loci stratified by sleep duration ', Nature Communications, vol. 10, no. 1, 5121 . https://doi.org/10.1038/s41467-019-12958-0
Nature communications, vol. 10, no. 1, pp. 5121
Publisher's version (útgefin grein).
Both short and long sleep are associated with an adverse lipid profile, likely through different biological pathways. To elucidate the biology of sleep-associated adverse lipid profile, we conduct multi-ance
Both short and long sleep are associated with an adverse lipid profile, likely through different biological pathways. To elucidate the biology of sleep-associated adverse lipid profile, we conduct multi-ance
Autor:
Pradeep Natarajan, Akhil Pampana, Sarah E. Graham, Sanni E. Ruotsalainen, James A. Perry, Paul S. de Vries, Jai G. Broome, James P. Pirruccello, Michael C. Honigberg, Krishna Aragam, Brooke Wolford, Jennifer A. Brody, Lucinda Antonacci-Fulton, Moscati Arden, Stella Aslibekyan, Themistocles L. Assimes, Christie M. Ballantyne, Lawrence F. Bielak, Joshua C. Bis, Brian E. Cade, Ron Do, Harsha Doddapaneni, Leslie S. Emery, Yi-Jen Hung, Marguerite R. Irvin, Alyna T. Khan, Leslie Lange, Jiwon Lee, Rozenn N. Lemaitre, Lisa W. Martin, Ginger Metcalf, May E. Montasser, Jee-Young Moon, Donna Muzny, Jeffrey R. O’Connell, Nicholette D. Palmer, Juan M. Peralta, Patricia A. Peyser, Adrienne M. Stilp, Michael Tsai, Fei Fei Wang, Daniel E. Weeks, Lisa R. Yanek, James G. Wilson, Goncalo Abecasis, Donna K. Arnett, Lewis C. Becker, John Blangero, Eric Boerwinkle, Donald W. Bowden, Yi-Cheng Chang, Yii-Der I. Chen, Won Jung Choi, Adolfo Correa, Joanne E. Curran, Mark J. Daly, Susan K. Dutcher, Patrick T. Ellinor, Myriam Fornage, Barry I. Freedman, Stacey Gabriel, Soren Germer, Richard A. Gibbs, Jiang He, Kristian Hveem, Gail P. Jarvik, Robert C. Kaplan, Sharon L. R. Kardia, Eimear Kenny, Ryan W. Kim, Charles Kooperberg, Cathy C. Laurie, Seonwook Lee, Don M. Lloyd-Jones, Ruth J. F. Loos, Steven A. Lubitz, Rasika A. Mathias, Karine A. Viaud Martinez, Stephen T. McGarvey, Braxton D. Mitchell, Deborah A. Nickerson, Kari E. North, Aarno Palotie, Cheol Joo Park, Bruce M. Psaty, D. C. Rao, Susan Redline, Alexander P. Reiner, Daekwan Seo, Jeong-Sun Seo, Albert V. Smith, Russell P. Tracy, Ramachandran S. Vasan, Sekar Kathiresan, L. Adrienne Cupples, Jerome I. Rotter, Alanna C. Morrison, Stephen S. Rich, Samuli Ripatti, Cristen Willer, NHLBI Trans-Omics for Precision Medicine (TOPMed) Consortium, FinnGen, Gina M. Peloso
Publikováno v:
Nature Communications
Nature Communications, Vol 12, Iss 1, Pp 1-14 (2021)
Nature Communications, Vol 12, Iss 1, Pp 1-14 (2021)
Autosomal genetic analyses of blood lipids have yielded key insights for coronary heart disease (CHD). However, X chromosome genetic variation is understudied for blood lipids in large sample sizes. We now analyze genetic and blood lipid data in a hi
Autor:
Fuli Yu, Josef Coresh, Zhuoyi Huang, Ginger A. Metcalf, Xiaoming Liu, Navin Rustagi, Elena V. Feofanova, Alanna C. Morrison, Christie M. Ballantyne, Bing Yu, Richard A. Gibbs, Donna M. Muzny, Eric Boerwinkle
Publikováno v:
The American Journal of Human Genetics. 100:205-215
Whole-genome sequencing (WGS) allows for a comprehensive view of the sequence of the human genome. We present and apply integrated methodologic steps for interrogating WGS data to characterize the genetic architecture of 10 heart- and blood-related t
Autor:
Lucia A. Hindorff, Diana A Chirinos-Medina, Charles Kooperberg, Gerardo Heiss, Cara L. Carty, Misa Graff, Christy L. Avery, Christie M. Ballantyne, Martha L. Daviglus, Katie Nishimura, Ran Tao, Ulrike Peters, Nathan Pankratz, Kari E. North, Christopher A. Haiman, Maja Barbalić, Dongquan Chen, Loic Le Marchand, Weihong Tang, José Luis Ambite, Lyle G. Best, Dana C. Crawford, Iona Cheng, Christopher S. Carlson, Rocio I. Pereira, Stephanie A. Bien, Themistocles L. Assimes, Myriam Fornage, Alexander P. Reiner, Jonathan M. Kocarnik, Petra Bůžková, Melissa A. Richard, Jeffrey Haessler, Gregory A. Talavera, Andrea Z LaCroix
Publikováno v:
Human molecular genetics, vol 27, iss 16
Kocarnik, Jonathan M; Richard, Melissa; Graff, Misa; Haessler, Jeffrey; Bien, Stephanie; Carlson, Chris; et al.(2018). Discovery, fine-mapping, and conditional analyses of genetic variants associated with C-reactive protein in multiethnic populations using the Metabochip in the Population Architecture using Genomics and Epidemiology (PAGE) study.. Human molecular genetics, 27(16), 2940-2953. doi: 10.1093/hmg/ddy211. UC San Diego: Retrieved from: http://www.escholarship.org/uc/item/6gb1b9h7
Kocarnik, Jonathan M; Richard, Melissa; Graff, Misa; Haessler, Jeffrey; Bien, Stephanie; Carlson, Chris; et al.(2018). Discovery, fine-mapping, and conditional analyses of genetic variants associated with C-reactive protein in multiethnic populations using the Metabochip in the Population Architecture using Genomics and Epidemiology (PAGE) study.. Human molecular genetics, 27(16), 2940-2953. doi: 10.1093/hmg/ddy211. UC San Diego: Retrieved from: http://www.escholarship.org/uc/item/6gb1b9h7
C-reactive protein (CRP) is a circulating biomarker indicative of systemic inflammation. We aimed to evaluate genetic associations with CRP levels among non-European-ancestry populations through discovery, fine-mapping and conditional analyses. A tot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0fa3d0897d6c2e97683fe73c5e3b64fd
https://escholarship.org/uc/item/6gb1b9h7
https://escholarship.org/uc/item/6gb1b9h7
Autor:
Robert N. Doughty, Marcus E. Kleber, Ulrich Laufs, Aroon D. Hingorani, Vinicius Tragante, Joachim Thiery, Eva Ringdal Pedersen, Sarah Triem, Andreas Leiherer, Alexandra Filips, Kenan Direk, Alexandre F.R. Stewart, Petra A. Lenzini, W.H. Wilson Tang, Thimoteus Speer, Roelof A.J. Smit, Hooman Allayee, Eric Boerwinkle, Ioannis Petrakis, George Thanassoulis, Christoph Sinning, Domenico Girelli, Heinrich V. Groesdonk, Yan Gong, Lutz P. Breitling, A. Mark Richards, Vicky A. Cameron, Benjamin D. Horne, Ruth McPherson, Gard Frodahl Tveitevåg Svingen, Dietrich Rothenbacher, Christopher Labos, Jaana Hartiala, Louise Pilote, Imo E. Hoefer, Christie M. Ballantyne, Ute Mons, Wolfgang Koenig, Bernhard K. Krämer, Stephen Zewinger, Vei-Vei Lee, Danilo Fliser, Ragnar O. Vilmundarson, Stefan Blankenberg, Julie A. Johnson, Riyaz S. Patel, Mira Klug, Christian Werner, Efthymia Vlachopoulou, H Brenner, Daniel Kofink, Michael V. Holmes, James C. Engert, Christopher P. Nelson, Agneta Siegbahn, Axel Mündlein, J. Wouter Jukema, Marek Sanak, Marcin P. Kaczor, Peter S. Braund, Markus Scholz, Niclas Eriksson, Markku S. Nieminen, Christoph Waldeyer, Salim S. Virani, Winfried März, Raymond O McCubrey, Stanley L. Hazen, Heinz Drexel, Yi-An Ko, Nicola Martinelli, Renate B. Schnabel, Hubert Scharnagl, Oliviero Olivieri, Wojciech Szczeklik, Grethe S. Tell, Nilesh J. Samani, Gustav Smith, James M. Brophy, Ottar Nygård, Naveed Sattar, Juha Sinisalo, Richard T. Jennings, Tatjana Stojakovic, Stella Trompet, Emil Hagström, Axel Åkerblom, John A. Spertus, Claes Held, Gerard Pasterkamp, Frank Beutner, Folkert W. Asselbergs, Anna P. Pilbrow, Rhonda M. Cooper-DeHoff, Arshed A. Quyyumi, Christoph H. Saely, Lars Wallentin, Sharon Cresci, Igor Karp, Amand F. Schmidt, Peter Bogaty, Reijo Laaksonen, Graciela E. Delgado, Karl J. Lackner
Publikováno v:
The Lancet Diabetes & Endocrinology, 5(7), 534. Elsevier BV
The Lancet Diabetes & Endocrinology
The Lancet Diabetes and Endocrinology, 5(7), 534-543
The Lancet Diabetes & Endocrinology
The Lancet Diabetes and Endocrinology, 5(7), 534-543
Background: \ud \ud Lipoprotein(a) concentrations in plasma are associated with cardiovascular risk in the general population. Whether lipoprotein(a) concentrations or LPA genetic variants predict long-term mortality in patients with established coro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::59f799185e5cc555a1851f944871990a
http://hdl.handle.net/10138/299248
http://hdl.handle.net/10138/299248
Autor:
Yan A. Meng, Stacey Gabriel, Brendan J. Keating, Monte S. Willis, Alexander P. Reiner, Lisa W. Martin, James S. Pankow, Ulrike Peters, Emma K. Larkin, Myron D. Gross, Joshua C. Bis, Paul L. Auer, Jaclyn Ellis, Taylor Young, Susan Redline, Emelia J. Benjamin, Guillaume Lettre, Ethan M. Lange, Josée Dupuis, James G. Wilson, Jerome I. Rotter, Ervin R. Fox, Carola Marzi, Vasan S. Ramachandran, Renate B. Schnabel, Leslie A. Lange, Russell P. Tracy, Jin Li, Christie M. Ballantyne, Jeremy D. Walston, Wolfgang Koenig, Deborah N. Farlow, Cameron D. Palmer, Peter Durda, Jens Baumert, George J. Papanicolaou
Publikováno v:
Ellis, J; Lange, EM; Li, J; Dupuis, J; Baumert, J; Walston, JD; et al.(2014). Large multiethnic Candidate Gene Study for C-reactive protein levels: Identification of a novel association at CD36 in African Americans. Human Genetics, 133(8), 985-995. doi: 10.1007/s00439-014-1439-z. UCLA: Retrieved from: http://www.escholarship.org/uc/item/25j7f1cp
Human genetics, vol 133, iss 8
Ellis, J; Lange, EM; Li, J; Dupuis, J; Baumert, J; Walston, JD; et al.(2014). Large multiethnic Candidate Gene Study for C-reactive protein levels: Identification of a novel association at CD36 in African Americans. Human Genetics, 133(8), 985-995. doi: 10.1007/s00439-014-1439-z. UCLA: Retrieved from: http://www.escholarship.org/uc/item/3kb9g06m
Human genetics, vol 133, iss 8
Ellis, J; Lange, EM; Li, J; Dupuis, J; Baumert, J; Walston, JD; et al.(2014). Large multiethnic Candidate Gene Study for C-reactive protein levels: Identification of a novel association at CD36 in African Americans. Human Genetics, 133(8), 985-995. doi: 10.1007/s00439-014-1439-z. UCLA: Retrieved from: http://www.escholarship.org/uc/item/3kb9g06m
C-reactive protein (CRP) is a heritable biomarker of systemic inflammation and a predictor of cardiovascular disease (CVD). Large-scale genetic association studies for CRP have largely focused on individuals of European descent. We sought to uncover
Autor:
Anton J. M. de Craen, Catherine E. de Keyser, Xiaohui Li, Joshua C. Bis, Jerome I. Rotter, J. Wouter Jukema, Stephen S. Rich, Kerri L. Wiggins, Eoin O'Brien, Oscar H. Franco, Yongmei Liu, Peter S. Sever, André G. Uitterlinden, Ching-Ti Liu, Michael R. Barnes, P. Eline Slagboom, Daniel S. Evans, Bruce M. Psaty, L. Adrienne Cupples, Fernando Rivadeneira, Joshua C. Denny, Paul M. McKeigue, Neil R Poulter, Rudi G. J. Westendorp, Sue Shaw-Hawkins, Gudny Eiriksdottir, Paul N. Durrington, Alice M. Arnold, Ronald M. Krauss, Paul M. Ridker, Marie-Pierre Dubé, Graham A. Hitman, Til Stürmer, Jean-Claude Tardif, Christie M. Ballantyne, Christopher J. O'Donnell, Susan R. Heckbert, Eric A. Whitsel, Deborah A. Nickerson, Kenneth Rice, Russell A. Wilke, Benoit J. Arsenault, Nicholas L. Smith, Helen R. Warren, Steven R. Cummings, Helen M. Colhoun, Andrew Neil, Vilmundur Gudnason, QiPing Feng, Patricia B. Munroe, Eric Boerwinkle, Nona Sotoodehnia, Wei-Qi Wei, Colin N. A. Palmer, Christy L. Avery, Denis C. Shields, Ian Ford, Bruno H. Stricker, John Betteridge, David J. Stott, S. Matthijs Boekholdt, Thomas Lumley, Charles M. Stein, G. Kees Hovingh, Brendan M. Buckley, Albert V. Smith, Harshal Deshmukh, Y. D.I. Chen, Ramachandran S. Vasan, Naveed Sattar, Bryan J. Barratt, Tamara B. Harris, Albert Hofman, Stella Trompet, Wendy Post, Joshua D. Smith, Fredrik Nyberg, Alice Stanton, Mark J. Caulfield, Kent D. Taylor, Fangui Sun, Daniel I. Chasman, Jeanette M. Stafford, Roelof A.J. Smit, L. J. Launer, Iris Postmus, Xiuqing Guo, John J. P. Kastelein
Publikováno v:
Journal of Medical Genetics, 53(12), 835
Journal of Medical Genetics, 53(12), 835-845. BMJ Publishing Group
Postmus, I, Warren, H R, Trompet, S, Arsenault, B J, Avery, C L, Bis, J C, Chasman, D I, de Keyser, C E, Deshmukh, H A, Evans, D S, Feng, Q, Li, X, Smit, R A J, Smith, A V, Sun, F, Taylor, K D, Arnold, A M, Barnes, M R, Barratt, B J, Betteridge, J, Boekholdt, S M, Boerwinkle, E, Buckley, B M, Chen, Y-D I, de Craen, A J M, Cummings, S R, Denny, J C, Dubé, M P, Durrington, P N, Eiriksdottir, G, Ford, I, Guo, X, Harris, T B, Heckbert, S R, Hofman, A, Hovingh, G K, Kastelein, J J P, Launer, L J, Liu, C-T, Liu, Y, Lumley, T, McKeigue, P M, Munroe, P B, Neil, A, Nickerson, D A, Nyberg, F, O'Brien, E, O'Donnell, C J, Post, W, Poulter, N, Vasan, R S, Rice, K, Rich, S S, Rivadeneira, F, Sattar, N, Sever, P, Shaw-Hawkins, S, Shields, D C, Slagboom, P E, Smith, N L, Smith, J D, Sotoodehnia, N, Stanton, A, Stott, D J, Stricker, B H, Stürmer, T, Uitterlinden, A G, Wei, W-Q, Westendorp, R G J, Whitsel, E A, Wiggins, K L, Wilke, R A, Ballantyne, C M, Colhoun, H M, Cupples, L A, Franco, O H, Gudnason, V, Hitman, G, Palmer, C N A, Psaty, B M, Ridker, P M, Stafford, J M, Stein, C M, Tardif, J-C, Caulfield, M J, Jukema, J W, Rotter, J I & Krauss, R M 2016, ' Meta-analysis of genome-wide association studies of HDL cholesterol response to statins ', Journal of Medical Genetics . https://doi.org/10.1136/jmedgenet-2016-103966
Journal of medical genetics, vol 53, iss 12
Journal of medical genetics, 53(12), 835-845. BMJ Publishing Group
Journal of Medical Genetics, 53(12), 835-845. BMJ Publishing Group
Postmus, I, Warren, H R, Trompet, S, Arsenault, B J, Avery, C L, Bis, J C, Chasman, D I, de Keyser, C E, Deshmukh, H A, Evans, D S, Feng, Q, Li, X, Smit, R A J, Smith, A V, Sun, F, Taylor, K D, Arnold, A M, Barnes, M R, Barratt, B J, Betteridge, J, Boekholdt, S M, Boerwinkle, E, Buckley, B M, Chen, Y-D I, de Craen, A J M, Cummings, S R, Denny, J C, Dubé, M P, Durrington, P N, Eiriksdottir, G, Ford, I, Guo, X, Harris, T B, Heckbert, S R, Hofman, A, Hovingh, G K, Kastelein, J J P, Launer, L J, Liu, C-T, Liu, Y, Lumley, T, McKeigue, P M, Munroe, P B, Neil, A, Nickerson, D A, Nyberg, F, O'Brien, E, O'Donnell, C J, Post, W, Poulter, N, Vasan, R S, Rice, K, Rich, S S, Rivadeneira, F, Sattar, N, Sever, P, Shaw-Hawkins, S, Shields, D C, Slagboom, P E, Smith, N L, Smith, J D, Sotoodehnia, N, Stanton, A, Stott, D J, Stricker, B H, Stürmer, T, Uitterlinden, A G, Wei, W-Q, Westendorp, R G J, Whitsel, E A, Wiggins, K L, Wilke, R A, Ballantyne, C M, Colhoun, H M, Cupples, L A, Franco, O H, Gudnason, V, Hitman, G, Palmer, C N A, Psaty, B M, Ridker, P M, Stafford, J M, Stein, C M, Tardif, J-C, Caulfield, M J, Jukema, J W, Rotter, J I & Krauss, R M 2016, ' Meta-analysis of genome-wide association studies of HDL cholesterol response to statins ', Journal of Medical Genetics . https://doi.org/10.1136/jmedgenet-2016-103966
Journal of medical genetics, vol 53, iss 12
Journal of medical genetics, 53(12), 835-845. BMJ Publishing Group
BACKGROUND: In addition to lowering low density lipoprotein cholesterol (LDL-C), statin therapy also raises high density lipoprotein cholesterol (HDL-C) levels. Inter-individual variation in HDL-C response to statins may be partially explained by gen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6fe0a35109caf7e4148e155075671133
http://hdl.handle.net/1887/113227
http://hdl.handle.net/1887/113227
Autor:
Christie M. Ballantyne, Taylor J. Maxwell, Chiadi E Ndumele, Eric Boerwinkle, Cameron Guild, James M. Cheverud
Publikováno v:
Genetics. 195:1397-1405
Relationship loci (rQTL) exist when the correlation between multiple traits varies by genotype. rQTL often occur due to gene-by-gene (G × G) or gene-by-environmental interactions, making them a powerful tool for detecting G × G. Here we present an
Autor:
Sekar Kathiresan, Susan R. Heckbert, Ariel Brautbar, Maja Barbalić, Ron C. Hoogeveen, Bing Yu, Vijay Nambi, Kenneth Rice, Bruce M. Psaty, Eric Boerwinkle, Thomas H. Mosley, Christie M. Ballantyne, Weihong Tang, Jerome I. Rotter, Christopher DeFilippi, Christopher J. O'Donnell
Publikováno v:
Circulation: Cardiovascular Genetics. 6:82-88
Background— High levels of cardiac troponin T, measured by a highly sensitive assay (hs-cTnT), are strongly associated with incident coronary heart disease and heart failure. To date, no large-scale genome-wide association study of hs-cTnT has been