Zobrazeno 1 - 10
of 31
pro vyhledávání: '"Li, Wei"'
Autor:
Chun Yang, Yexiong Tan, Xiao-Fan Feng, Yun-Han Ma, Zhi-Wen Ding, Zheng-Hua Wan, Hongyang Wang, Yun-Kai Lin, Tian-Yi Jiang, Yu-Fei Pan, Lifeng Huang, Li-Wei Dong, Xiaoni Kong, Yuan-Yuan Shi
Publikováno v:
Hepatology. 71:2005-2022
Background and aims Cancer cell survival depends on the balance between reactive oxygen species production and scavenging, which is regulated primarily by NRF2 during tumorigenesis. Here, we demonstrate that deletion of RBP5-mediating protein (RMP) i
Autor:
Min Zhang, Li Wei, Saiyang Xie, Yun Xing, Wenke Shi, Xiaofeng Zeng, Si Chen, Shasha Wang, Wei Deng, Qizhu Tang
Publikováno v:
Frontiers in Pharmacology
Frontiers in Pharmacology, Vol 12 (2021)
Frontiers in Pharmacology, Vol 12 (2021)
Background: As a plant-derived polycyclic phenolic carboxylic acid isolated from Salvia miltiorrhiza, lithospermic acid (LA) has been identified as the pharmacological management for neuroprotection and hepatoprotection. However, the role and mechani
Autor:
Li-Bo Tang, Shu-Xin Ma, Yuehui Zheng, Zhi-Hang Chen, Jia Li, Guo Zong, Zi-Juan Tang, Min-Li Wei
Publikováno v:
Journal of International Medical Research, Vol 49 (2021)
The Journal of International Medical Research
The Journal of International Medical Research
Objective To investigate the effects and potential mechanism of action of shikonin (SHK) on the development of ovarian follicles and female germline stem cells (FGSCs). Methods Female Kunming adult mice were administered SHK (0, 20 and 50 mg/kg) by o
Autor:
Li Wei, Wei Miao, Kevin W. Williams, Qin Xu, Zhao Gao, Jiecheng Zhang, Yuan Zhang, Bo Cheng, Chunhui Song, Yong Gao, Weihang Gao, Zehong Yang, Yongsheng Chang, Xingping Yang, Changhui Liu
Publikováno v:
Oxidative Medicine and Cellular Longevity, Vol 2020 (2020)
Oxidative Medicine and Cellular Longevity
Oxidative Medicine and Cellular Longevity
Acetaminophen (APAP) toxicity leads to severe acute liver injury (ALI) by inducing excessive oxidative stress, inflammatory response, and hepatocyte apoptosis. Imperatorin (IMP) is a furanocoumarin from Angelica dahurica, which has antioxidant and an
Autor:
Lei Zhao, Jun Liu, Song He, Xiaoyu Zhang, Wei Tan, Ping Yang, Chunxiao Su, Xiong-Zhong Ruan, Guoqing Zuo, Li Wei, Yao Chen, Yaxi Chen
Publikováno v:
Lipids in Health and Disease, Vol 17, Iss 1, Pp 1-9 (2018)
Lipids in Health and Disease
Lipids in Health and Disease
Background Accumulating evidence suggests that activated hepatocytes are involved in the deposition of the excess extracellular matrix during liver fibrosis via the epithelial to mesenchymal transition. Lipid accumulation in hepatocytes are implicate
5-HMF Attenuates Liver Fibrosis in CCl4-Plus-Alcohol-Induced Mice by Suppression of Oxidative Stress
Publikováno v:
Journal of Nutritional Science and Vitaminology. 63:35-43
The aim of this study was to investigate the effects of 5-hydroxymethyl-2-furfural (5-HMF) on liver fibrosis induced by carbon tetrachloride (CCl4) and alcohol. Male ICR mice were treated with CCl4 dissolved in olive oil (10% v/v, 2.5 μg/L) intraper
Autor:
Jian-Zhang Cheng, Li Wei, Qing-Qing Fu, María Teresa Moreno-Flores, Javier Sierra, Hua You, Hua-Rong Yu
Publikováno v:
Cellular and Molecular Neurobiology. 37:1043-1054
Olfactory ensheathing cells (OECs) are a type of glia from the mammalian olfactory system, with neuroprotective and regenerative properties. β-Amyloid peptides are a major component of the senile plaques characteristic of the Alzheimer brain. The am
Publikováno v:
Cellular and Molecular Neurobiology. 37:513-525
This study was designed to investigate the protective effects of extracellular superoxide dismutase (SOD3) against amyloid beta (Aβ25-35)-induced damage in human neuroblastoma SH-SY5Y cells and to elucidate the mechanisms responsible for this benefi
Autor:
Hongyang Wang, Shuai Huang, Liang Tang, Min Zeng, Xu Zhou, Ming-Da Wang, Li-Wei Dong, Chen-Jie Qin, He-Xin Yan, Ling-Hao Zhao, Meng-Chao Wu, Gong-Bo Fu, Han Wu, Hui-Lu Zhang
Publikováno v:
Hepatology. 63:1272-1286
Solid tumors often suffer from suboptimal oxygen and nutrient supplies. This stress underlies the requirement for metabolic adaptation. Aberrantly activated de novo lipogenesis is critical for development and progression of human hepatocellular carci
Publikováno v:
Environmental Pollution. 208:416-425
Di-(2-ethylhexyl) phthalate (DEHP) is used extensively in many personal care and consumer products, resulting in widespread non-occupational human exposure through multiple routes and media. DEHP has various deleterious effects including hepatotoxici