Zobrazeno 1 - 10
of 2 702
pro vyhledávání: '"11"'
Autor:
Weiguo Jin, Ling-Feng Min, Chao Sun, Yiwei Fan, Xiaolin Wang, Hongcan Shi, Shichun Lu, Yusheng Shu
Publikováno v:
Cancer Biol Ther
Evidence suggests that Tripartite Motif Containing 11 (TRIM11) has pro-tumor activity in human non-small cell lung cancer (NSCLC). However, the roles and underlying mechanisms of TRIM11 in NSCLC have not yet been fully elucidated. In this work, human
Publikováno v:
Molecular Oncology
Molecular Oncology, Vol 12, Iss 10, Pp 1689-1705 (2018)
Molecular Oncology, Vol 12, Iss 10, Pp 1689-1705 (2018)
Ovarian cancer (OC) is one of the most intractable diseases, exhibiting tremendous molecular heterogeneity and lacking reliable methods for screening, resulting in late diagnosis and widespread peritoneal dissemination. Menopausal estrogen replacemen
Autor:
Maria Abbondanza Pantaleo, Margherita Nannini, Giorgio Ercolani, Cristian Lolli, Donatella Santini, Valentina Indio, Milena Urbini, Antonio Daniele Pinna, Michelangelo Fiorentino, Maristella Saponara, Annalisa Astolfi, Massimo Del Gaudio, Guido Biasco, Anna Mandrioli, Maria Giulia Pirini, Giovanni Brandi, Lidia Gatto
Publikováno v:
Oncotarget
// Maristella Saponara 1,* , Milena Urbini 2,* , Annalisa Astolfi 2 , Valentina Indio 2 , Giorgio Ercolani 3 , Massimo Del Gaudio 3 , Donatella Santini 4 , Maria Giulia Pirini 4 , Michelangelo Fiorentino 5 , Margherita Nannini 1 , Cristian Lolli 1 ,
Autor:
Kai Hsi Hsu, Tzu Ying Li, Ya Chin Hou, Hao-Chen Wang, Yan Shen Shan, Yuan Shuo Hsueh, Ying Jui Chao
Publikováno v:
Clinical cancer research : an official journal of the American Association for Cancer Research. 22(14)
Purpose: KIT mutations, the most prevalent genetic event in gastrointestinal stromal tumors (GIST), are associated with malignant features and poor prognosis. Aggressive GISTs possess a high propensity to spread to the liver. This study aimed to expl
Publikováno v:
Molecular Cancer Research. 3:453-461
Ring finger proteins serve many vital functions within the cell. We have identified RNF11, a novel 154-amino acid ring finger–containing protein, which is elevated in breast cancer. Within its ring finger domain, RNF11 contains an AKT phosphorylati
Publikováno v:
International journal of oncology. 41(2)
Endometrial carcinoma is the most common gynaecological malignancy. There is however a lack of curative therapies, especially for patients diagnosed with late stage, recurrent or aggressive disease, who have a poor prognosis. Interleukin (IL) 11 is a
Publikováno v:
Cancer Letters. 95:201-205
E5a of HPV-11 is a transforming oncogene. Previously, we have shown that E5a constitutively activates the expression of protooncogene c-jun by transcriptional regulation through the AP-1 binding site in the c-jun promoter. In the present study, we us
Autor:
Ayumi Yoshizaki, Kazuyuki Yamazumi, Toshiyuki Nakayama, Ichiro Sekine, Mitsuru Taba, Yuichi Yakata
Publikováno v:
International Journal of Oncology.
Previous investigations have shown that interleukin (IL)-11/IL-11 receptor alpha-chain (IL-11Ralpha), a member of the PI3K, MAPK and JAK-STAT activating family of cytokines/receptors, correlates with the regulation of tumor progression. In this study
Publikováno v:
Cancer Research. 71:P2-03
Our laboratory studied the gene expression profiles of a series of T47D variant cell lines with differential insulin receptor substrate (IRS) adaptor protein expression to develop predictive IGF-I pathway biomarkers. We identified an IGF-I-induced ge
Autor:
Boris N. Kholodenko, Joan Grindlay, O. Sturm, Richard J. Orton, A. von Kriegsheim, Walter Kolch, Marc R. Birtwistle, David Gilbert
Publikováno v:
European Journal of Cancer Supplements. 8:3
A relevant example comprises the epidermal growth factor (EGF) and the respective receptor tyrosine kinases, namely ErbB-1/EGFR and HER2, which belong to a prototype signaling module that drives carcinoma development. The extended module includes two