Zobrazeno 1 - 10
of 2 085
pro vyhledávání: '"11"'
Autor:
Amanda B. Spurdle, Koichi Matsuda, Yoshio Miki, Teruhiko Yoshida, Kokichi Sugano, Atsushi Takahashi, Chieko Tamura, Yukihide Momozawa, Yusuke Iwasaki, Toyomasa Katagiri, Michael T. Parsons, Makoto Hirata, Yoichiro Kamatani, Seigo Nakamura, Michiaki Kubo
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-7 (2018)
Nature Communications
Nature Communications
Pathogenic variants in highly penetrant genes are useful for the diagnosis, therapy, and surveillance for hereditary breast cancer. Large-scale studies are needed to inform future testing and variant classification processes in Japanese. We performed
Publikováno v:
PLoS ONE, Vol 8, Iss 5, p e62951 (2013)
PLoS ONE
PLoS ONE
BACKGROUND AND AIMS: Considering the indication of adjuvant therapy, the recurrence risk for primary gastrointestinal stromal tumor (GIST) after surgery needs to be accurately estimated. However, current risk stratification schemes may still have roo
Publikováno v:
PLoS ONE
PLoS ONE, Vol 7, Iss 5, p e37255 (2012)
PLoS ONE, Vol 7, Iss 5, p e37255 (2012)
Background: Alternative splicing across exon 11 produces several BRCA1 isoforms. Their proportion varies during the cell cycle, between tissues and in cancer suggesting functional importance of BRCA1 splicing regulation around this exon. Although the
Publikováno v:
PLoS ONE
PLoS ONE, Vol 8, Iss 7, p e68695 (2013)
PLoS ONE, Vol 8, Iss 7, p e68695 (2013)
Background and objectivePrevious investigations of glioma risk in women have focused on oral contraceptive (OC), hormone replacement therapy (HRT), and reproductive factors. However, the results of published studies were inconclusive and inconsistent
Autor:
Rudolf Oehler, Suzann Baumann, Winfried Rebhandl, Manfred Weninger, Thomas M. Benkoe, Carlos A. Reck, Mario Pones
Publikováno v:
PLoS ONE
PLoS ONE, Vol 8, Iss 3, p e58720 (2013)
PLoS ONE, Vol 8, Iss 3, p e58720 (2013)
OBJECTIVE: A prospective study to investigate the pattern of pro- and anti-inflammatory cytokine responses in neonates with surgical necrotizing enterocolitis (NEC) and identify those cytokines being the most promising for future research. METHODS: A
Publikováno v:
PLoS ONE, Vol 16, Iss 8, p e0256416 (2021)
PLoS ONE
PLoS ONE
The identification of novel therapies, new strategies for combination of therapies, and repurposing of drugs approved for other indications are all important for continued progress in the fight against lung cancers. Antibodies that target immune chec
Autor:
Farrel J. Buchinsky, Nicole Ruszkay, William Valentino, Kevin W. Lollar, Dalya Guris, Robert W. Bastian, Craig S. Derkay, John E. McClay, Charles M. Myer
Publikováno v:
PLoS ONE, Vol 15, Iss 3, p e0230106 (2020)
PLoS ONE
PLoS ONE
Background Recurrent respiratory papillomatosis (RRP) is characterized by repeated formation of papillomas in the respiratory tract and is caused by human papillomavirus (HPV) types 6 and 11. Women with genital HPV infection are slow to develop weak
Autor:
Carmen de Torres, Parineeta Arora, Parmjit S. Jat, Artur Brandt, Barbara Leube, Jaume Mora, Brigitte Royer-Pokora, Katharina Löhers, Manfred Beier
Publikováno v:
PLoS ONE, Vol 11, Iss 5, p e0155561 (2016)
PLoS ONE
PLoS ONE
We describe a stromal predominant Wilms tumor with focal anaplasia and a complex, tumor specific chromosome 11 aberration: a homozygous deletion of the entire WT1 gene within a heterozygous 11p13 deletion and an additional region of uniparental disom
Autor:
Jennifer M. Carr, Edith A. Perez, Julia E. Crook, Bianca C. Axenfeld, Panos Z. Anastasiadis, Daniel J. Serie, Alvaro Moreno-Aspitia, Brian M. Necela, Jennifer M. Kachergus, Ryan W. Feathers, Pooja Advani, E. Aubrey Thompson, Nadine Norton, Xochiquetzal J. Geiger
Publikováno v:
PLoS ONE
PLoS ONE, Vol 11, Iss 4, p e0153411 (2016)
PLoS ONE, Vol 11, Iss 4, p e0153411 (2016)
Background Invasive lobular carcinoma (ILC) comprises approximately ~10–20% of breast cancers. In general, multifocal/multicentric (MF/MC) breast cancer has been associated with an increased rate of regional lymph node metastases. Tumor heterogenei
Publikováno v:
PLoS ONE
PLoS ONE, Vol 15, Iss 1, p e0227180 (2020)
PLOS ONE
PLoS ONE, Vol 15, Iss 1, p e0227180 (2020)
PLOS ONE
Recent evidence shows that the disruption of constitutive insulated neighbourhoods might lead to oncogene dysregulation. We present here a systematic pan-cancer characterisation of the associations between constitutive boundaries and genome alteratio