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Publikováno v:
Medicinal Chemistry. 18:273-287
Aim: To synthesize and evaluate the fused heterocyclic imidazopyridine oxime as a reactivator against paraoxon inhibited acetylcholinesterase. Background: Organophosphorus compounds (OPs) include parathion, malathion, chlorpyrifos, monocrotophos, and
Publikováno v:
Journal of Colloid and Interface Science. 607:1651-1660
The rational integration of chemotherapy and hydroxyl radical (·OH)-mediated chemodynamic therapy (CDT) via functional metal-organic frameworks (MOF) carriers has great potential in cancer therapy. In this work, aminotriazole (3-AT) doped polyhedral
Publikováno v:
Journal of Thrombosis and Haemostasis. 20:285-292
The disulfide bond is a covalent bond formed between the sulfur atoms of two cysteine residues in proteins. Our understanding of the role of these ubiquitous bonds in protein function has changed dramatically over the past decade. Initially thought t
Publikováno v:
Journal of Colloid and Interface Science. 607:1516-1526
Sorafenib-mediated chemotherapy is currently the first choice for hepatocellular carcinoma (HCC) that cannot be surgically excised, and can significantly improve the survival of patients. However, its poor water solubility restricts its bioavailabili
Autor:
Shencong Lv, Henghui Wang, Lei Gao, Guoying Zhu, Wenjie Gao, Ping Li, Li Zhan, Xiaofei Zhang, Yong Yan
Publikováno v:
Journal of Food Protection. 85:213-219
Salmonella , a major foodborne pathogen, causes severe gastrointestinal disease in people and animals worldwide. Plasmid-borne mcr-1 , which confers colistin resistance in Salmonella, has significant epidemiological interest for public health safety.
Publikováno v:
Internal Medicine. 61:429-432
Optic neuritis (ON) is a rare complication of tumor necrosis factor (TNF)-α inhibitors. The autoantibody serostatus, treatment, and outcome of TNF-α inhibitor-associated ON remain unclear. We herein report a 50-year-old woman with ON following adal
Autor:
Norberto Rodriguez-Baez, Douglas Mogul, Jordan J. Feld, Kathleen B. Schwarz, David Wong, Lia Laura Lewis-Ximenez, Kin Seng Liem, Adam J. Gehring, Simon C. Ling, Bettina E. Hansen, Jeffery H. Teckman, Alexandra Johnson Valiente, Philip J. Rosenthal, Georg M. Lauer, Sarah Jane Schwarzenberg, Karen F. Murray, Harry L.A. Janssen
Publikováno v:
The Journal of infectious diseases, 225(3), 470-475. Oxford University Press
Liver damage in hepatitis B is immune driven and correlates with inflammatory markers in patient serum. There is no comparison of these markers to determine if inflammatory profiles are distinct to different types of liver damage across patients at d
Autor:
Carlos Rodríguez-Lucas, Javier Fernández, Alberto Bahamonde, Carmen Raya, Rosario Muñoz, M. R. Rodicio, Antonio Quiroga
Publikováno v:
Microbial Drug Resistance. 28:217-221
Vancomycin-resistant Enterococcus faecium (VREfm) is one of the most important nosocomial pathogens with limited therapeutic alternatives. In this study, we followed the trends of VREfm and E. faecium causing bloodstream infections (BSIs) in a Spanis
Autor:
Minka Zivkovic, Mark Roest, Thomas Renné, Chantal C. Clark, Arjan D. Barendrecht, Coen Maas, Hinde El Otmani, Simone M. Smits, Wariya Sanrattana, Nadine D van Kleef, Steven de Maat
Publikováno v:
Journal of Thrombosis and Haemostasis. 20:353-365
BACKGROUND Occlusive thrombi are not homogeneous in composition. The core of a thrombus is rich in activated platelets and fibrin while the outer shell contains resting platelets. This core is inaccessible to plasma proteins. We produced a fusion pro
Autor:
Hisham Ali Waggiallah
Publikováno v:
Saudi Journal of Biological Sciences, Vol 29, Iss 2, Pp 1073-1078 (2022)
Saudi Journal of Biological Sciences
Saudi Journal of Biological Sciences
COVID-19 deteriorates type II pneumocytes and damages the alveolar immunologic balancing process through the inadvertent activation of a sequence of localized and general inflammatory responses. Due to an aggregation of uncleaved angiotensin II, the