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of 133
pro vyhledávání: ''
Autor:
Jie Ji, Hongzhi Wang, Huanhu Zhang, Dahai Zhao, Shujie Wang, Rui Tao, Bo Hong, Jinfu Nie, Jian Qi, Ruifang Sun, Xiaopeng Zhang, Yanzhe Liu, Qingmei Deng
Publikováno v:
Cancer Science
Cell‐free methylated DNA immunoprecipitation and high‐throughput sequencing (cfMeDIP‐seq) is a new bisulfite‐free technique, which can detect the whole‐genome methylation of blood cell‐free DNA (cfDNA). Using this technique, we identified
Autor:
Thomas A. Treibel, Tim Brooks, Rosemary J. Boyton, Marianna Fontana, Mahdad Noursadeghi, Joseph M Gibbons, UK COVIDsortium Investigators, James C. Moon, David Butler, Mala K. Maini, Angelique Smit, Jane E. Sackville-West, Corinna Pade, Catherine J. Reynolds, Amanda Semper, Ashley Otter, Ana M. Valdes, Áine McKnight, Charlotte Manisty, Katia Menacho, Teresa Cutino-Moguel, Benjamin M. Chain, Daniel M. Altmann
Publikováno v:
Science (New York, N.y.)
A boost from infection During clinical trials of severe acute respiratory syndrome coronavirus 2 vaccines, no one who had survived infection with the virus was tested. A year after the pandemic was declared, vaccination of previously infected persons
Autor:
Alessandra Franzetti Pellanda, Jun Siong Low, Michela Perotti, Sandra Jovic, Laurent Perez, Rosalia Cacciatore, Christian Garzoni, Maira Biggiogero, Federico Mele, Josipa Jerak, Mathilde Foglierini, Antonio Lanzavecchia, Daniela Vaqueirinho, Federica Sallusto, Paolo Ferrari, David Jarrossay, Alessandro Ceschi, Tatiana Terrot, Antonino Cassotta
Publikováno v:
Science (New York, N.y.)
Probing CD4 T cell immunity to SARS-CoV-2 A better understanding of CD4 + T cell responses to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is crucial to the design of effective next-generation vaccines. Low et al. defined and estimate
Autor:
Khoa D. Nguyen, Grace H. Jean, Claus U. Niemann, Katherine J. L. Jackson, Tho D. Pham, Ramona A. Hoh, Emily Haraguchi, Katharina Röltgen, Julie Parsonnet, Yi Liu, Sandra C. A. Nielsen, Fan Yang, Kari C. Nadeau, Ji-Yeun Lee, Scott D. Boyd, Krishna M. Roskin, Robert S. Ohgami, Eleanor M. Osborne, Oliver F. Wirz
Publikováno v:
Science (New York, N.y.)
Kids armed with anti-coronavirus B cells It remains unclear whether B cell repertoires against coronaviruses and other pathogens differ between adults and children and how important these distinctions are. Yang et al. analyzed blood samples from youn
Publikováno v:
Biotechniques
IgA nephropathy (IgAN) is an autoimmune disease characterized by renal glomerular immunodeposits enriched for galactose-deficient IgA1 (Gd-IgA1; autoantigen) with the corresponding IgG autoantibodies. Despite the known contribution of Gd-IgA1 to IgAN
Autor:
Ludvic Zrinzo, Peter Brown, Harith Akram, Ashwini Oswal, Marwan Hariz, Marjan Jahanshahi, Thomas Foltynie, Vladimir Litvak, James Gratwicke, Laszlo Zaborszky
Publikováno v:
Brain
Parkinson’s disease dementia (PDD) and dementia with Lewy bodies (DLB) are related conditions that are associated with cholinergic system dysfunction. Dysfunction of the nucleus basalis of Meynert (NBM), a basal forebrain structure that provides th
Autor:
Min Ni, Anbo Zhou, Tammy Taylor, Mark G. Lewis, Anthony L. Cook, Maciel Porto, Olga Gonzalez, Neil Stahl, Adelekan Oyejide, Laurent Pessaint, Dharani Ajithdoss, John Dutton, Jack Greenhouse, Kendra J. Alfson, Edward J. Dick, Kathryn Lanza, Richard Copin, Christos A. Kyratsous, Bret J Musser, Kusha Mohammadi, Ricardo Carrion, Vaneesha Ali, Elizabeth Clemmons, Michal Gazi, George D. Yancopoulos, Nicole Negron, Hilary M. Staples, Hanne Leth Andersen, Gurinder S. Atwal, Alina Baum, Andrew J. Murphy, Renita Brown, Yenny Goez-Gazi, Yi Wei, Carmen Bartley, Benjamin Klaffke
Publikováno v:
Science
Science (New York, N.y.)
Science (New York, N.y.)
A beneficial cocktail Since the start of the coronavirus disease 2019 (COVID-19) pandemic, considerable effort has gone into generating and characterizing neutralizing antibodies that could be used as therapeutics. Studies in humanized mice and conva
Autor:
Sharmilee Gnanapavan, Meleri Jones, Liaqat Ali, David Baker, Klaus Schmierer, Angray S. Kang, Gavin Giovannoni, Luke Gammon, Georgia R. Leisegang, Gauri Saxena
Publikováno v:
Biotechniques
Aim: The humanized anti-CD52 monoclonal antibody alemtuzumab depletes lymphocytes and is currently used to treat relapsing multiple sclerosis. During treatment, anti-alemtuzumab antibodies may develop and reduce effective lymphocyte depletion in futu
Autor:
David Llobet-Navas, Jose M. Silva, Partha Mukhopadhyay, Meredith L Davis, Rachel L Werner, Laura Devis-Jauregui, Erin A. Nekritz, Koon-Kiu Yan, Ruth Rodriguez-Barrueco, Jiyang Yu
Publikováno v:
EMBO Rep
During the female lifetime, the expansion of the epithelium dictated by the ovarian cycles is supported by a transient increase in the mammary epithelial stem cell population (MaSCs). Notably, activation of Wnt/β-catenin signaling is an important tr
Autor:
Simone L. Schonkeren, Glenn Rademakers, Remond J.A. Fijneman, Pieter Vanden Berghe, Meike de Wit, David W. Threadgill, Kasper M.A. Rouschop, Amy Marie Holland, Tim G. A. M. Wolfs, Alexander Koch, Laura Moonen, Edith van den Boezem, Jaleesa R M Van der Meer, Marion J.J. Gijbels, Werend Boesmans, Tom G. Keulers, Robert M.W. Hofstra, Veerle Melotte, Nathalie Vaes, Connie R. Jimenez, Kim M. Smits, Jeroen Demmers
Publikováno v:
EMBO Reports, 22(6):e51913. Wiley-Blackwell
Embo Reports, 22(6):e51913. Wiley
EMBO reports, 22(6):e51913. Wiley-Blackwell
Vaes, N, Schonkeren, S L, Rademakers, G, Holland, A M, Koch, A, Gijbels, M J, Keulers, T G, de Wit, M, Moonen, L, van der Meer, J R M, van den Boezem, E, Wolfs, T G A M, Threadgill, D W, Demmers, J, Fijneman, R J A, Jimenez, C R, Vanden Berghe, P, Smits, K M, Rouschop, K M A, Boesmans, W, Hofstra, R M W & Melotte, V 2021, ' Loss of enteric neuronal Ndrg4 promotes colorectal cancer via increased release of Nid1 and Fbln2 ', EMBO Reports, vol. 22, no. 6, e51913, pp. e51913 . https://doi.org/10.15252/embr.202051913
EMBO Reports
Embo Reports, 22(6):e51913. Wiley
EMBO reports, 22(6):e51913. Wiley-Blackwell
Vaes, N, Schonkeren, S L, Rademakers, G, Holland, A M, Koch, A, Gijbels, M J, Keulers, T G, de Wit, M, Moonen, L, van der Meer, J R M, van den Boezem, E, Wolfs, T G A M, Threadgill, D W, Demmers, J, Fijneman, R J A, Jimenez, C R, Vanden Berghe, P, Smits, K M, Rouschop, K M A, Boesmans, W, Hofstra, R M W & Melotte, V 2021, ' Loss of enteric neuronal Ndrg4 promotes colorectal cancer via increased release of Nid1 and Fbln2 ', EMBO Reports, vol. 22, no. 6, e51913, pp. e51913 . https://doi.org/10.15252/embr.202051913
EMBO Reports
The N‐Myc Downstream‐Regulated Gene 4 (NDRG4), a prominent biomarker for colorectal cancer (CRC), is specifically expressed by enteric neurons. Considering that nerves are important members of the tumor microenvironment, we here establish differe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a7a8c4ad6b520a89d4afdcc7f87119a2
https://lirias.kuleuven.be/handle/123456789/675939
https://lirias.kuleuven.be/handle/123456789/675939