Zobrazeno 1 - 10
of 357
pro vyhledávání: '"11"'
Autor:
Saloua Ladeb, Nour Skouri, Ines Safra, Abderrahman Abdelkefi, Tarek Ben Othman, Melika Ben Ahmed, Karima Mrad, Cyrine Ben Ali, Asma Beldi-Ferchiou
Publikováno v:
PLoS ONE
PLoS ONE, Public Library of Science, 2017, 12 (4), pp.e0174835. ⟨10.1371/journal.pone.0174835⟩
PLoS ONE, Vol 12, Iss 4, p e0174835 (2017)
PLoS ONE, Public Library of Science, 2017, 12 (4), pp.e0174835. ⟨10.1371/journal.pone.0174835⟩
PLoS ONE, Vol 12, Iss 4, p e0174835 (2017)
cited By 1; International audience; Sustained activation of JAK/STAT3 signaling pathway is classically described in Multiple Myeloma (MM). One explanation could be the silencing of the JAK/STAT suppressor genes, through the hypermethylation of SHP-1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d82eb8cbdb8082b6fd7f9298a868ed1
https://hal.archives-ouvertes.fr/hal-01565820/document
https://hal.archives-ouvertes.fr/hal-01565820/document
Autor:
Paula Mercedes Berguer, Isabel Piazzon, Alejandra Duarte, Juliana Mundiñano, Irene Nepomnaschy, Daniela Lorenzo
Publikováno v:
CONICET Digital (CONICET)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
PLoS ONE
PLoS ONE, Vol 11, Iss 9, p e0162456 (2016)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
PLoS ONE
PLoS ONE, Vol 11, Iss 9, p e0162456 (2016)
B-cell superantigens (Sags) bind to conserved sites of the VH or VL regions of immunoglobulin molecules outside their complementarity-determining regions causing the apoptosis of normal cognate B cells. No attempts to investigate whether B-cell Sags
Publikováno v:
PLoS ONE, Vol 9, Iss 1, p e85619 (2014)
PLoS ONE
PLoS ONE
Head and Neck Squamous Cell Carcinoma (HNSCC) encompasses malignancies that arise in the mucosa of the upper aerodigestive tract. Recent high throughput DNA sequencing revealed HNSCC genes mutations that contribute to several cancer cell characterist
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d62f6b8cb69cdfae8484e1234b12f9af
http://hdl.handle.net/10722/214443
http://hdl.handle.net/10722/214443
Autor:
Hannah Breit, Benjamin Kefas, Christel Herold-Mende, Anindya Dutta, Kaitlyn Marks, Roger Abounader, Michael Synowitz, Desiree Floyd, Rainer Glass, Ying Zhang, Bijan K. Dey, Benjamin Purow
Publikováno v:
PLoS ONE, Vol 9, Iss 5, p e96239 (2014)
PLoS ONE
PLoS ONE
Glioblastoma is the most common and lethal primary brain tumor. Tumor initiation and recurrence are likely caused by a sub-population of glioblastoma stem cells, which may derive from mutated neural stem and precursor cells. Since CD133 is a stem cel
Publikováno v:
PLoS ONE, Vol 9, Iss 3, p e91582 (2014)
PLoS ONE
PLoS ONE
Reactive oxygen species (ROS) regulate diverse cellular functions by triggering signal transduction events, such as Src and mitogen-activated protein (MAP) kinases. Here, we report the role of caveolin-1 and Src homology 2 domain-containing protein t
Autor:
Liang Zhou, Wesley W. Bodie, Jessica Felthousen, Robert Z. Orlowski, Shuang Chen, Xin Yan Pei, Lora Kramer, Michael W. Sanderson, Leena E. Youssefian, Yun Dai, Steven Grant, Yukie Takabatake
Publikováno v:
PLoS ONE
PLoS ONE, Vol 9, Iss 3, p e89064 (2014)
PLoS ONE, Vol 9, Iss 3, p e89064 (2014)
The anti-apoptotic protein Mcl-1 plays a major role in multiple myeloma (MM) cell survival as well as bortezomib- and microenvironmental forms of drug resistance in this disease. Consequently, there is a critical need for strategies capable of target
Autor:
Anna Miller, Jolene J. Windle, Hisashi Harada, Mark A. Hicks, Amanda C. Richardson, Wataru Nakajima
Publikováno v:
PLoS ONE
PLoS ONE, Vol 8, Iss 4, p e60685 (2013)
PLoS ONE, Vol 8, Iss 4, p e60685 (2013)
Paclitaxel (Taxol)-induced cell death requires the intrinsic cell death pathway, but the specific participants and the precise mechanisms are poorly understood. Previous studies indicate that a BH3-only protein BIM (BCL-2 Interacting Mediator of cell
Autor:
Gizem Karsli-Uzunbas, Paul H. M. Harrison, Tayirjan Taylor Isimjan, Ozgur Kutuk, Huveyda Basaga, Cagri Bodur
Publikováno v:
PLoS ONE, Vol 8, Iss 2, p e56369 (2013)
PLoS ONE
PLoS ONE
Pramanicin (PMC) is an antifungal agent that was previously demonstrated to exhibit antiangiogenic and anticancer properties in a few in vitro studies. We initially screened a number of PMC analogs for their cytotoxic effects on HCT116 human colon ca
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::832e98ba260de4f8c7164c10f010cc16
Autor:
Sunil K. Noothi, Subrahmanya D. Vallabhapurapu, Sang-Oh Yoon, Veena Potluri, Charles H. Lawrie, Sivakumar Vallabhapurapu, James J. Driscoll
Publikováno v:
PLoS ONE, Vol 8, Iss 7, p e66121 (2013)
PLoS ONE
PLoS ONE
Multiple Myeloma (MM) is an incurable plasma cell cancer that is caused by several chromosomal translocations and gene deletions. Although deregulation of several signaling pathways including the Nuclear Factor-Kappa B (NF-κB) pathway has been repor
Publikováno v:
PLoS ONE
PLoS ONE, Vol 8, Iss 1, p e55406 (2013)
PLoS ONE, Vol 8, Iss 1, p e55406 (2013)
The microRNA, miR-24, inhibits B cell development and promotes myeloid development of hematopoietic progenitors. Differential regulation of cell survival in myeloid and lymphoid cells by miR-24 may explain how miR-24′s affects hematopoietic progeni