Zobrazeno 1 - 10
of 584
pro vyhledávání: '"35"'
Autor:
Mark Vermeulen, Esmeralda van der Helm, Jort Vellinga, Benoit Christophe Stephan Callendret, Marina Koning, Jan Serroyen, Maria Grazia Pau, Kerstin Wunderlich, Roland Zahn, Hanneke Schuitemaker, Dirk Spek, Adile Gecgel, Barbara Petronella Sanders, Jerome Custers, Marija Vujadinovic, Masha Stalknecht, Karin de Boer
Publikováno v:
Human gene therapy, 29(3), 337-351. Mary Ann Liebert Inc.
Genetic vaccines based on replication-incompetent adenoviral (AdV) vectors are currently in clinical development. Monovalent AdV vectors express one antigen from an expression cassette placed in most cases in the E1 region. For many vaccines, inclusi
Autor:
I. G. A. Ruether, Dimitri Komiotis, T.G. Dimitriou, Panayotis Markoulatos, Z. Kyriakopoulou, M. Papacharalampous, E. Toska, D. Tsakogiannis
Publikováno v:
Molecular and Cellular Probes. 29:13-18
Long-term infection with high-risk HPV genotypes is the leading cause of cervical cancer. In the present study a Duplex Real-time PCR assay was developed in order to identify HPV types 16, 18, 31, 35, 51 and 66 in three reactions, through SYBR green
Autor:
Gunilla B. Karlsson Hedestam, André Lieber, William C. Adams, Richard A. Koup, Ronald J. Berenson, Karin Loré
Publikováno v:
J Gen Virol
The complement-regulatory protein CD46 is the primary receptor for human adenovirus type 35 (HAdV-35) and can regulate human immune-cell activation. CD4 + T-cells are critical for initiating and maintaining adaptive immunity elicited by infection or
Publikováno v:
Journal of Virological Methods. 177:55-63
The use of adenovirus type 35 (Ad35) as a vector in vaccine and gene therapy studies is promising due to its broad cell tropism and low seroprevalence in humans. However, to date, a simple and effective system for producing recombinant Ad35 (rAd35) h
Autor:
Gilbert, Cornut, Simon, Gagnon, Catherine, Hankins, Deborah, Money, Karina, Pourreaux, Eduardo L, Franco, François, Coutlée, Julio, Montaner
Publikováno v:
Journal of Medical Virology. 82:1168-1178
The L1 gene encodes for the major capsid protein of human papillomaviruses (HPV). There is limited information on the polymorphism of L1 for types related to HPV-16. This report explores the polymorphism of L1 in phylogenetically related types 31, 33
Publikováno v:
Gene Therapy. 14:912-919
Human CD46 (membrane cofactor protein), which serves as a receptor for a variety of pathogens, including strains of measles virus, human herpesvirus type 6 and Neisseria, is rapidly downregulated from the cell surface following infection by these pat
Publikováno v:
YAKUGAKU ZASSHI. 126:1013-1019
Recombinant Adenovirus (Ad) vectors are considered to be a promising gene delivery vehicle of high utility because they are easy to construct, can be produced at high titers, and efficiently transduce various types of cells. Ad vectors commonly used
Computational insights into the suicide inhibition of Plasmodium falciparum Fk506-binding protein 35
Autor:
Russell J. Boyd, Corey A. MacDonald
Publikováno v:
Bioorganicmedicinal chemistry letters. 25(16)
Malaria is a parasite affecting millions of people worldwide. With the risk of malarial resistance reaching catastrophic levels, novel methods into the inhibition of this disease need to be prioritized. The exploitation of active site differences bet
Publikováno v:
Journal of Interferon & Cytokine Research. 19:1245-1252
Nmi was initially identified through a yeast two-hybrid interaction with N-Myc but it also interacts with c-Myc, Max, Fos, and several other transcription factors, including signal transducer and activator of transcription (Stat) proteins. Nmi is an
Autor:
D. Tsakogiannis, Panayotis Markoulatos, P. Gortsilas, T.G. Dimitriou, I. G. A. Ruether, Z. Kyriakopoulou, E. Toska, V. Diamantidou
Publikováno v:
Archives of virology. 160(1)
The causal association between persistent human papillomavirus (HPV) infection and cervical cancer has lead to the development of a variety of molecular assays for HPV detection. The present study focused on the development of a simple, sensitive and