Zobrazeno 1 - 10
of 2 796
pro vyhledávání: ''
Publikováno v:
Medicina Clínica. 158:596-602
Background There is no a unified opinion in the treatment of IgA nephropathy. This prospective cohort study was to explore the effectiveness and safety of tacrolimus for treatment of IgA (Immunoglobulin A) nephropathy patients. Methods In this study,
Autor:
Szu-Chun Hsu, Ming Yao, Bor-Sheng Ko, Hsiu-Hsia Lin, Hwei-Fang Tien, Wen-Chien Chou, Shang-Yi Huang, Jih-Luh Tang, Shang-Ju Wu
Publikováno v:
Journal of the Formosan Medical Association. 121:643-651
BACKGROUND/PURPOSE Decorin is a small leucine-rich proteoglycan rich in extracellular matrix with potential antitumor activity. However, the role of decorin in hematological malignancies remains unclear, especially in the case of multiple myeloma (MM
Autor:
Hiroyuki Motoyama, Norifumi Kawada, Kohei Kotani, Akihiro Tamori, Naoshi Odagiri, Hideki Fujii, Hoang Hai, Le Thi Thanh Thuy, Atsushi Hagihara, Minh Phuong Dong, Masaru Enomoto, Ritsuzo Kozuka, Etsushi Kawamura, Sawako Uchida-Kobayashi, Kanako Yoshida
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-11 (2022)
Scientific Reports
Scientific Reports
Soluble immune checkpoint molecules are emerging novel mediators of immune regulation. However, it is unclear whether soluble immune checkpoint proteins affect the development of hepatocellular carcinoma (HCC) during nucleos(t)ide analogue (NA) treat
Autor:
Jeong-Hwan Yoon, Sook-Hyang Jeong, Si Ho Kim, Eun Sun Jang, Yoon Jun Kim, Gwang Hyeon Choi, Boo-ok Jang, Jin Wook Kim, Jeong Hoon Lee, Su Jong Yu, Kyunghan Lee, Yun Bin Lee, Eun Ju Cho, Jae Kyun Choi
Publikováno v:
Liver International. 42:320-329
BACKGROUND & AIMS This multicenter cohort study aimed to compare the real-world biochemical response rates during tenofovir alafenamide (TAF), tenofovir disoproxil fumarate (TDF), and entecavir (ETV) treatment in chronic hepatitis B virus (HBV) infec
Autor:
Andrey Sivkov, Svetlana Sivkova, Roman V. Gorenkov, Sergey Sivkov, Natalya P. Chernus, Tamara Savina
Publikováno v:
Lipids in Health and Disease, Vol 20, Iss 1, Pp 1-9 (2021)
Lipids in Health and Disease
Lipids in Health and Disease
Background To determine the effect of genetic polymorphism of drug transporters on the efficacy of treatment with Rosuvastatin, Atorvastatin and Simvastatin in patients with hyperlipidemia. Methods The study consists of 180 patients, aged 40–75 yea
Autor:
Gere Sunder-Plassmann, Michaela Gabriel, Andreas Gleiss, Walter H. Hörl, Matthias Lorenz, Thomas Prikoszovich, Bernhard Bielesz, Rossella Monteforte, Michael Wolzt
Publikováno v:
Clin J Am Soc Nephrol
Background and objectives Whether iron supplementation in patients on hemodialysis could be delivered by less frequent but higher single doses compared with the currently more common higher-frequency schedules of lower single iron doses is unknown. D
Autor:
Yujin Sohn, Jong-Beack Lim, Nam Su Ku, Joon Sup Yeom, Yunsuk Cho, Jin Young Ahn, Jung Ho Kim, Jun Yong Choi, Sang-Guk Lee, John Hoon Rim, Hye Seong, Su Jin Jeong, Moo Hyun Kim, YaeJee Baek, Jong Hoon Hyun, Young Goo Song
Publikováno v:
BMC Infectious Diseases, Vol 21, Iss 1, Pp 1-8 (2021)
BMC Infectious Diseases
BMC Infectious Diseases
Background Pharmacokinetic-pharmacodynamic (PK/PD) targets of vancomycin therapy have been recognized for methicillin-resistant Staphylococcus aureus infections but not for other gram-positive bacterial infections. Therefore, we investigated whether
Autor:
Jens U. Marquardt, Edward K. Geissler, Matthias Hornung, Hans J. Schlitt, Kilian Weigand, Tim Zimmermann, G Peschel, Akinbami Adenugba, Hauke Lang, P Kupke, Henrik Junger, Jens M. Werner
Publikováno v:
Transplantation. 105:2226-2238
Background. Chronic hepatitis C virus (HCV) infection is characterized by activation of natural killer (NK) cells. Here, we asked whether HCV elimination by sofosbuvir-based direct-acting antivirals (DAAs) and the addition of ribavirin (RBV) improve
Autor:
Olivier Barbier, Nisanne S. Ghonem, James L. Boyer, David N. Assis, Christopher Hemme, Gina M. Gallucci, Jocelyn Trottier
Publikováno v:
Hepatology Communications
Hepatology Communications, Vol 5, Iss 12, Pp 2035-2051 (2021)
Hepatology Communications, Vol 5, Iss 12, Pp 2035-2051 (2021)
Accumulation of cytotoxic bile acids (BAs) during cholestasis can result in liver failure. Glucuronidation, a phase II metabolism pathway responsible for BA detoxification, is regulated by peroxisome proliferator–activated receptor alpha (PPARα).
Autor:
Koenraad Van den Abbeele, Vadir Baktash, Constantinos G Missouris, Amit K J Mandal, Pirabakaran Kandiah, Theodora Katsanouli, Ryan Goindoo, Asmita Pandey, Randeep S Heer, Charlotte Wenban, Afiyah Ajaz
Publikováno v:
Journal of Medical Virology
Aims We have previously demonstrated that vitamin D deficiency might be associated with worse outcomes in hospitalised Covid-19 patients. The aim of our study was to explore this relationship with dexamethasone therapy. Methods We prospectively studi