Zobrazeno 1 - 10
of 28
pro vyhledávání: '"D. C. Rao"'
Genome-wide association studies suggest sex-specific loci associated with abdominal and visceral fat
Autor:
David R. Jacobs, Yun J. Sung, Treva Rice, Mark A. Sarzynski, John Blangero, S. Sidney, Barbara Sternfeld, James G. Terry, D. C. Rao, Claude Bouchard, Tuomo Rankinen, Jean-Pierre Després, Louis Pérusse, Peter T. Katzmarzyk, Myriam Fornage, J. Jeffrey Carr, Joanne E. Curran, Sujoy Ghosh
Publikováno v:
International journal of obesity (2005)
Background To identify loci associated with abdominal fat and replicate prior findings, we performed genome-wide association (GWA) studies of abdominal fat traits: subcutaneous adipose tissue (SAT), visceral adipose tissue (VAT), total adipose tissue
Autor:
Yii-Der Ida Chen, Stephen S. Rich, Steven C. Hunt, Stephen A. Mandel, Barry I. Freedman, D. C. Rao, Donna K. Arnett, Richard H. Myers, Ping An
Publikováno v:
Diabetes. 55:551-558
Genome-wide linkage scans were carried out using a multipoint variance components method in white and black families of the NHLBI Hypertension Genetic Epidemiology Network (HyperGEN) study to identify quantitative trait loci (QTLs) for pancreatic β-
Autor:
James S. Pankow, Gerardo Heiss, Michael A. Province, Steven C. Hunt, Aldi T. Kraja, Richard H. Myers, D. C. Rao, Cora E. Lewis
Publikováno v:
Obesity Research. 13:1885-1890
As part of the Hypertension Genetic Epidemiology Network study, genome scans were performed in two ethnicities on the categorical metabolic syndrome (MetS). Genome scans were performed also on the factor scores produced by factor analysis (quantitati
Autor:
Richard N. Bergman, Jean Bergeron, Tuomo Rankinen, Treva Rice, D. C. Rao, Nicola Santoro, Claude Bouchard, Arthur S. Leon, James S. Skinner, Margarita Teran-Garcia, Jean-Pierre Després
Publikováno v:
Diabetes. 54:2251-2255
We investigated the associations between the hepatic lipase gene (LIPC) −514C>T polymorphism and lipases, lipoproteins, and insulin sensitivity (Si) responses to exercise training. Hepatic lipase and lipoprotein lipase activities, plasma lipoprotei
Publikováno v:
American Journal of Physiology-Endocrinology and Metabolism. 288:E1168-E1178
The beneficial effects of regular physical activity on insulin sensitivity (SI) and glucose tolerance are well documented, with considerable heterogeneity in responsiveness to exercise training (ET). To find novel candidate genes for ET-induced impro
Autor:
Jack H. Wilmore, James S. Skinner, Arthur S. Leon, Y.A. Kesäniemi, Claude Bouchard, Olavi Ukkola, Tuomo Rankinen, Timo A. Lakka, D. C. Rao
Publikováno v:
Obesity Research. 13:829-834
Protein tyrosine phosphatase 1B (PTPN1) affects the regulation of insulin signaling and energy metabolism. We studied whether polymorphisms in the PTPN1 gene impact body fat distribution in the HERITAGE Family Study cohort in 502 white and 276 black
Autor:
Jack H. Wilmore, S. John Weisnagel, Normand G. Boulé, Tuomo Rankinen, Timo A. Lakka, Hanna Maaria Lakka, D. C. Rao, Richard N. Bergman, Yvon C. Chagnon, Olavi Ukkola, James S. Skinner, Treva Rice, Arthur S. Leon, Claude Bouchard
Publikováno v:
Diabetes. 53:1603-1608
We recently reported that a genomic region close to the leptin locus was linked to fasting insulin response to exercise training in nondiabetic white subjects. We tested the hypothesis that common exonic variants in the leptin (LEP) and leptin recept
Autor:
Tuomo Rankinen, James S. Skinner, Ingrid B. Borecki, Claude Bouchard, Mary F. Feitosa, Arthur S. Leon, D. C. Rao, Jack H. Wilmore
Publikováno v:
Metabolism. 52:35-41
The relationship between sex hormone-binding globulin (SHBG) concentrations and body fat accumulation and distribution is governed by complex dynamic factors, which may involve common genetic and/or environmental factors. The current study investigat
Autor:
James S. Skinner, D. C. Rao, Tuomo Rankinen, George Argyropoulos, Arthur S. Leon, Michael A. Province, Doni R. Neufeld, Claude Bouchard, Treva Rice, Jack H. Wilmore
Publikováno v:
The Journal of Clinical Endocrinology & Metabolism. 87:4198-4202
The mouse agouti-related protein (AGRP) is a powerful appetite effector that results in hyperphagia and the development of obesity when administered intracerebroventricularly or when overexpressed in transgenic mice. Animal studies have also shown th
Autor:
James S. Skinner, Arthur S. Leon, Jacques Gagnon, D. C. Rao, Yuling Hong, Jack H. Wilmore, Louis Pérusse, Treva Rice, Claude Bouchard
Publikováno v:
Journal of Endocrinology. 170:485-492
Familial correlation analyses were used to evaluate the familial aggregation of plasma androgens and androgen glucuronides (testosterone (TESTO), dihydrotestosterone (DHT), androstane-3 alpha,17 beta-diol glucuronide (3 alpha-DIOL-G), and androsteron