Zobrazeno 1 - 10
of 301
pro vyhledávání: '"Ochi A"'
Autor:
Arisa Ochi, Yasumasa Ikeda, Naoki Kashihara, Kojiro Nagai, Kensei Taguchi, Masanori Tamaki, Ken-ichi Aihara, Hideharu Abe, Masashi Miyoshi, Craig R. Brooks, Hiroyuki Kadoya, Kenji Nishimura, Seiji Kishi
Publikováno v:
Biochemical and Biophysical Research Communications. 556:142-148
The relationship between cellular senescence and fibrosis in the kidney is being elucidated and we have identified it as therapeutic target in recent studies. Chronic kidney disease has also become a lifestyle disease, often developing on the backgro
Autor:
Kentaro Kawabe, Tomomasa Ibuki, Kiyohiro Yamazaki, Shinichiro Ochi, Yoko Mori, Yuki Ozaki, Yuta Yoshino, Jun-ichi Iga, Tetsuro Ohmori, Shu-ichi Ueno, Shusuke Numata
Publikováno v:
Neuropsychiatric Disease and Treatment. 16:441-446
Introduction: Although ATP-binding cassette sub-family A member 7 gene (ABCA7) is known to be associated with Alzheimer’s disease, the relationship between ABCA7 and schizophrenia has been unknown. Methods: Schizophrenia patients (n = 50; 24 males,
Publikováno v:
Journal of the American Medical Directors Association. 22(12)
Autor:
Nobumitsu Hanioka, Takashi Isobe, Hideto Jinno, Toshiko Tanaka-Kagawa, Sadayuki Ochi, Susumu Ohkawara
Publikováno v:
Toxicology in Vitro. 54:237-242
Di(2-ethylhexyl) phthalate (DEHP) is a widely used plasticizer that is rapidly metabolized to mono(2-ethylhexyl) phthalate (MEHP), an active metabolite, in mammals. In the present study, the hydrolysis of DEHP by the liver and intestinal microsomes o
Autor:
Hisao Nishijo, Susumu Urakawa, Takaya Oshima, Son Tien Nguyen, Naoto Fujita, Natsuki Goto, Kaho Takaishi, Ryosuke Ochi
Publikováno v:
PLoS ONE, Vol 16, Iss 9, p e0256655 (2021)
PLoS ONE
PLoS ONE
Metabolic disorders are associated with a higher risk of psychiatric disorders. We previously reported that 20-week-old Otsuka Long-Evans Tokushima fatty (OLETF) rats, a model of progressive type 2 diabetes, showed increased anxiety-like behavior and
Publikováno v:
Exp Gerontol
Skeletal muscle regeneration that follows acute injury is strongly influenced by interactions with immune cells that invade and proliferate in the damaged tissue. Discoveries over the past 20 years have identified many of the key mechanisms through w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::034ea35ee8509097b0764bbf57b56ffc
https://europepmc.org/articles/PMC7855614/
https://europepmc.org/articles/PMC7855614/
Autor:
Hisao Nishijo, Son Tien Nguyen, Taketoshi Ono, Duc Trung Le, Naoto Fujita, Kojiro Matsushita, Natsuki Goto, Ryosuke Ochi, Susumu Urakawa
Publikováno v:
The journal of physiological sciences : JPS. 70(1)
Metabolic disorders can induce psychiatric comorbidities. Both brain and neuronal composition imbalances reportedly induce an anxiety-like phenotype. We hypothesized that alterations of localized brain areas and cholecystokinin (CCK) and parvalbumin
Autor:
Hiroshi Kumon, Naoki Abe, Jun-ichi Iga, Shuken Boku, Keisuke Sekiya, Shu-ichi Ueno, Tasuku Nishihara, Yuta Yoshino, Yu Funahashi, Shinichiro Ochi
Publikováno v:
Scientific Reports
Scientific Reports, Vol 11, Iss 1, Pp 1-10 (2021)
Scientific Reports, Vol 11, Iss 1, Pp 1-10 (2021)
The pathophysiology of delayed carbon monoxide (CO) encephalopathy remains unclear. In this study, the effects of CO exposure on the dentate gyrus (DG) were investigated in a Wistar rat model by histochemical and molecular methods. Model rats showed
Autor:
Hideyuki Fujii, Tadachika Kudo, Kunihisa Kobayashi, Midori Minezaki, Tomohiro Shinagawa, Kentaro Ochi, Yuichi Takashi, Yuka Yamao, Shigeaki Mukoubara, Hanako Ohishi, Ichiro Abe, Makiko Abe, Kaoru Sugimoto, Kenji Ohe, Yasushi Ohnishi
Publikováno v:
Drug discoveriestherapeutics. 13(6)
Sodium glucose transporter 2 inhibitors (SGLT2is), new antidiabetic agents, were reported to improve not only glycemic parameters but also metabolic and circulatory parameters. Whereas, several adverse events caused by SGLT2is were also reported. We
Autor:
Shu Takeda, Hiroki Ochi
Leptin regulates bone remodeling through the central nervous system, in particular, the β-adrenergic system. β2-adrenergic receptor signaling in osteoblasts inhibits osteoblast differentiation and regulates RANKL expression and then increases bone
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9fbe841d287d1d5f67e6be0012deb74e
https://doi.org/10.1016/b978-0-12-801238-3.11224-3
https://doi.org/10.1016/b978-0-12-801238-3.11224-3