Zobrazeno 1 - 10
of 7 571
pro vyhledávání: ''
Autor:
Jianqiang Li, Hui Zhao, Pingping Li, Shuyin Zhi, Ruina Li, Lifang Li, Jian-Nan Gong, Guang Yang
Publikováno v:
Laboratory Investigation. 102:272-280
Patients with chronic obstructive pulmonary disease (COPD) are characterized by an imbalance between oxidant enzymes and antioxidant enzymes. In the present study, we explored the protective effect of vitamin E on COPD and the underlying mechanisms.
Autor:
Alice da Conceição Alves de Lima, George Jackson de Moraes Rocha, Paula Roberta da Silva, Maria do Carmo Alves de Lima, Luiz Carlos Alves, Pedro José Rolim Neto, Fábio André Brayner dos Santos, Thammyris Pires Souza, Jana M. Sandes, Iranildo José da Cruz Filho, Rosali Maria Ferreira da Silva
Publikováno v:
International Journal of Biological Macromolecules. 193:1799-1812
In this work, we investigated in vitro the antioxidant, cytotoxic and anti-leishmanial activities of a lignin extracted from the leaves of Morinda citrifolia. Initially, an analysis of the composition of the sheets was performed, then the lignin was
Publikováno v:
Biochemical and Biophysical Research Communications. 567:112-117
Grb2-associated-binding protein-2 (Gab2) is a member of the Gab/DOS family and functions as an adapter protein downstream of several growth factor signaling pathways. Gab2 is considered an Alzheimer's disease susceptibility gene. However, the role of
Autor:
Chandru Subramani, Rajkumar Singh Kalra, Sukant Garg, Jia Wang, Shubhra Agarwal, Ashish Kaul, Jaspreet Kaur Dhanjal, Vipul Kumar, Sudhanshu Vrati, Renu Wadhwa, Durai Sundar, Huayue Zhang, Sunil C. Kaul
Publikováno v:
International Journal of Biological Macromolecules
COVID-19 caused by SARS-CoV-2 corona virus has become a global pandemic. In the absence of drugs and vaccine, and premises of time, efforts and cost required for their development, natural resources such as herbs are anticipated to provide some help
Publikováno v:
Biochemical and Biophysical Research Communications. 559:21-27
Suppressor of cytokine signaling (SOCS) proteins are primarily feedback inhibitors of cytokine signaling. The two conserved domains of SOCS proteins have distinct functions. Src homology 2 (SH2) domain inhibits cytokine receptor, while SOCS box acts
Publikováno v:
Biochemical and Biophysical Research Communications. 556:106-113
Among all lung cancer cases, lung adenocarcinoma (LAC) represents nearly 40% and remains the leading cause of cancer deaths worldwide. Although the combination therapy of surgical treatment with radiotherapy, chemotherapy, and immunotherapy, has been
Autor:
Aliki Kapazoglou, Eirini Sarrou, Sophia Letsiou, Ioannis Ganopoulos, Aggeliki Karamaouna, Georgia Tanou, Athanasios Molassiotis, Aliki Xanthopoulou
Publikováno v:
Molecular Biology Reports. 48:4441-4448
There is a persistent interest in innovative and multifunctional ingredients in biology research. With regards to this, natural sources have an important role due to their multiple benefits. Thus, this study aims to present the pleiotropic activity o
Publikováno v:
Experimental & Molecular Medicine
Inflammation, oxidative stress, and protease–antiprotease imbalance have been suggested to be a pathogenic triad in chronic obstructive pulmonary disease (COPD). However, it is not clear how proteases interact with components of inflammatory pathwa
Publikováno v:
Journal of Biochemical and Molecular Toxicology. 35:1-11
Zerumin A (ZA) is one of the potential components of Curcuma amada rhizomes, and it has been shown to possess a variety of pharmacological activities. This study deals with the beneficial activity of ZA in lipopolysaccharide (LPS)-stimulated inflamma
Autor:
Luka Culibrk, Peter Schubert, Dana V. Devine, Edward M. Conway, Raymond P. Goodrich, Brankica Culibrk
Publikováno v:
Transfusion. 61:1551-1561
Background Accelerated development of the platelet (PLT) storage lesion upon pathogen inactivation (PI) is associated with the release of proteins from granules and platelet microvesicles (PMVs). Whether PI treatments alter the interaction between PL