Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Chen Liang"'
Autor:
Jie Hua, Jin Xu, Qingcai Meng, Xianjun Yu, Yubin Lei, Bo Zhang, Si Shi, Yiyin Zhang, Zhen Tan, Jiang Liu, Miaoyan Wei, Chen Liang
Publikováno v:
Aging (Albany NY)
Pancreatic ductal adenocarcinoma (PDAC) is one of the most fatal malignancies worldwide. Extensive enhancement of glycolysis and reprogramming of lipid metabolism are both associated with the development and progression of PDAC. Previous studies have
Autor:
Jie Hua, Chen Liang, Jin Xu, Yiyin Zhang, Bo Zhang, Jiang Liu, Qingcai Meng, Si Shi, Xianjun Yu
Publikováno v:
Autophagy
Pancreatic ductal adenocarcinoma (PDAC) is one of the most aggressive and lethal malignancies. Given that macroautophagy/autophagy activation is prevalent in PDAC, the dual roles of autophagy could be involved in PDAC heterogeneity. In this work, we
Autor:
Chen Liang, Guo-wen Tang, Wu Guoxing, Yonghui Xie, Hang Zhao, Gao Ping, Bin Cheng, Zhi-jiang Wang, Xi Gao
Publikováno v:
Micron. 150:103143
In order to explore the mechanism underlying chemosensation in Eocanthecona furcellata, the external morphology of its antennae and the type, quantity, distribution and ultrastructure of the sensilla were observed on both sexes of adults and 5th-inst
Autor:
Jundong Wang, Jianhai Zhang, Yongli Han, Michelle Shiao-Bin Eng, Chen Liang, Yuchen Zhu, Yan Shi, Zhiyuan Feng, Heping Zheng
Publikováno v:
Journal of Agricultural and Food Chemistry. 65:8966-8976
Fluoride is known to impair testicular function and decrease testosterone levels, yet the underlying mechanisms remain inconclusive. The objective of this study is to investigate the roles of autophagy in fluoride-induced male reproductive toxicity u
Autor:
Alicia Kerr, Veeral Shah, Leslie E. W. LaConte, Paras A. Patel, Chen Liang, Konark Mukherjee, Ching-Kang Chen, Michael A. Fox
Publikováno v:
Investigative Ophthalmology & Visual Science
Purpose Heterozygous mutations in the essential X-linked gene CASK associate with optic nerve hypoplasia (ONH) and other retinal disorders in girls. CASK+/- heterozygous knockout mice with mosaic CASK expression exhibit ONH with a loss of retinal gan
Autor:
Xiao-Di Yu, Na Niu, Shuai Zhang, Zhi-Ren Zhang, Tiffany L. Thai, He-Ping Ma, Ming-Ming Wu, Roy L. Sutliff, Bin-Lin Song, Jing Ma, Xu Yang, Valerie Linck, Li Zou, Yu-Jia Zhai, Bao-Long Zhang, Yong-Xu Cai, Qiang Yue, Qiu-Shi Wang, Chen Liang
Publikováno v:
Br J Pharmacol
Background and purpose We have shown that cholesterol is synthesized in the principal cells of renal cortical collecting ducts (CCD) and stimulates the epithelial sodium channels (ENaC). Here we have determined whether lovastatin, a cholesterol synth
Autor:
Huiling Jin, Chen Liang, Rajesh Prajapati, Motohiko Sato, Wenqian Cai, Masanari Umemura, Takayuki Fujita, Satoshi Okumura, Kenji Suita, Yoshihiro Ishikawa, Utako Yokoyama, Yuko Hidaka
Publikováno v:
Biochemical and Biophysical Research Communications. 475:1-7
Type 5 adenylyl cyclase (AC5) plays an important role in the development of chronic catecholamine stress-induced heart failure and arrhythmia in mice. Epac (exchange protein activated by cAMP), which is directly activated by cAMP independent of prote
Publikováno v:
Human Molecular Genetics
Hum Mol Genet
Hum Mol Genet
G4C2 repeat expansions in an intron of C9ORF72 cause the most common familial amyotrophic lateral sclerosis and frontotemporal dementia (collectively, C9ALS/FTD). Mechanisms and mediators of C9ALS/FTD pathogenesis remain poorly understood. C9orf72 an
Publikováno v:
The Journal of International Medical Research
Journal of International Medical Research, Vol 46 (2018)
Journal of International Medical Research, Vol 46 (2018)
Objective This study aimed to investigate the mechanism by which Chinese herbal medicine ulcer oil (UO) accelerates ulcer healing in a diabetic ulcer rat model. Methods Sprague Dawley rats were allocated at random into four groups: a control group, a
Autor:
Shirong Li, Ge Liangpeng, Hongli Li, Chen Liang, Wenguang Chen, Chuan Cao, Li Xiaoge, Rui Guo, Linlin Chai
Publikováno v:
In Vitro Cellular & Developmental Biology - Animal. 51:578-585
Epidermal stem cells could contribute to skin repair through the migration of cells from the neighboring uninjured epidermis, infundibulum, hair follicle, or sebaceous gland. However, little is known about the factors responsible for the complex biol