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Publikováno v:
Antioxidantsredox signaling. 37(7-9)
SIGNIFICANCE Reactive oxygen species (ROS) contribute to multiple aspects of peripheral nervous system (PNS) biology ranging from physiological processes (e.g. axonal outgrowth and regeneration), to pathophysiology (e.g. nerve degeneration). Although
Autor:
Jae-Hyun Lee, Chang-Min Lee, Joyce H. Lee, Mun-Ock Kim, Jin Wook Park, Suchitra Kamle, Bedia Akosman, Erica L. Herzog, Xue Yan Peng, Jack A. Elias, Chun Geun Lee
Publikováno v:
Am J Respir Cell Mol Biol
RationalePulmonary fibrosis is a devastating lung disease with few therapeutic options. Chitinase 1 (CHIT1), an 18 glycosyl hydrolase family member, contributes to the pathogenesis of pulmonary fibrosis through regulation of Transforming Growth Facto
Publikováno v:
Antioxidants & Redox Signaling. 37:451-480
SIGNIFICANCE Currently 10-15% of couples in reproductive age face infertility issues. More importantly, male factor contributes to 50% of these cases (either alone or in combination with female causes). Amongst various reasons, impaired sperm functio
Publikováno v:
Journal of Investigative Dermatology. 142:1755-1758
Sezary syndrome (SS) is an aggressive form of cutaneous T-cell lymphoma with a diverse set of mutated genes. Using previously published datasets, we reanalyzed the copy number landscape of SS and detected whole genome amplifications in 20% of all SS
Autor:
Jian Wang, Zichao Feng, Zhaoyang Zhong, Qichao Qi, Wenjie Li, Jiwei Wang, Ning Yang, Qing Zhang, Bin Huang, Chen Qiu, Xiaofei Liu, Yaotian Hu, Anjing Chen, Wenxing Jin, Wenjing Zhou, Zhiyi Xue
Publikováno v:
Cell Cycle
Background: Nucleolar and spindle associated protein 1 (NUSAP1) is an indispensable mitotic regulator, which has been reported to be involved in the development, progression, and metastasis of several types of cancer. Here, we investigated the expres
Autor:
Marion Marchand, Jérémie Teillon, Stéphane Germain, Claudia Umana-Diaz, Florence Ruggiero, Corinne Ardidie-Robouant, Marilyne Malbouyres, Christophe Guilluy, A. Barret, Catherine Monnot, Laurent Muller, Romain Salza, Sylvie Ricard-Blum, Yoann Atlas, Cathy Pichol-Thievend, Philippe Girard
Publikováno v:
Matrix Biology
Matrix Biology, 2023, 88, pp.33-52. ⟨10.1016/j.matbio.2019.11.003⟩
Matrix Biology, 2023, 88, pp.33-52. ⟨10.1016/j.matbio.2019.11.003⟩
International audience; Lysyl oxidases are major actors of microenvironment and extracellular matrix (ECM) remodeling. These cross-linking enzymes are thus involved in many aspects of physiopathology, including tumor progression, fibrosis and cardiov
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d14f0be8bc5a3b088af8e2d6c98fd4df
https://hal.science/hal-04029951
https://hal.science/hal-04029951
Autor:
Yoshiyuki Matsuo
Publikováno v:
Antioxidants & Redox Signaling. 36:984-1000
SIGNIFICANCE The presence of a large number of thioredoxin superfamily members suggests a complex mechanism of redox-based regulation in mammalian cells. However, whether these members are functionally redundant or play separate and distinct roles in
Autor:
Hans Ackerman, Mitchell J. Weiss, Miriam M. Cortese-Krott, Steven E. Brooks, Linda Columbus, T C Steven Keller, Christophe Lechauve, Brant E. Isakson, Alexander S. Keller
Publikováno v:
Physiol Rev
Globin proteins exist in every cell type of the vasculature, from erythrocytes to endothelial cells, vascular smooth muscle cells, and peripheral nerve cells. Many globin subtypes are also expressed in muscle tissues (including cardiac and skeletal m
Autor:
Susanna Lopez Kostka, Björn E. Clausen, Ari Waisman, Dominika Lukas, Esther von Stebut, Kordula Kautz-Neu, Nir Yogev, Bernhard Holzmann
Publikováno v:
Journal of Investigative Dermatology. 142:1230-1233
Autor:
Jianqiang Li, Hui Zhao, Pingping Li, Shuyin Zhi, Ruina Li, Lifang Li, Jian-Nan Gong, Guang Yang
Publikováno v:
Laboratory Investigation. 102:272-280
Patients with chronic obstructive pulmonary disease (COPD) are characterized by an imbalance between oxidant enzymes and antioxidant enzymes. In the present study, we explored the protective effect of vitamin E on COPD and the underlying mechanisms.