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Publikováno v:
Bioengineered, Vol 13, Iss 2, Pp 3620-3633 (2022)
Preeclampsia (PE) is a pregnancy disorder characterized by excessive trophoblast cell death. This study aims to explore the exact mechanism of the ubiquitination level of FUN14 domain containing 1 (FUNDC1) in mitophagy and injury in hypoxic trophobla
Autor:
Paula Szczesniewska, Justyna Otulakowska-Skrzynska, Anna Krahel, Tomasz Hanć, Maria Gawriolek, Amadeusz Hernik, Marta Tyszkiewicz-Nwafor, Ewa Bryl, Monika Dmitrzak-Weglarz, Agnieszka Słopień, Elzbieta Paszynska, Yves Boucher, Szymon Rzatowski
Publikováno v:
Mediators of Inflammation, Vol 2021 (2021)
Mediators of Inflammation
Mediators of Inflammation
Background. The use of easily accessible biomarkers for assessing young patients’ health is weighty. This cohort study is aimed at measuring stress/immune biomarkers in the saliva of healthy school-age children and comparing subgroups according to
Publikováno v:
DNA and Cell Biology. 40:1356-1368
In this study, we aimed to explore cyclophosphamide (Cytoxan) response-associated genes and constructed a model to predict the prognosis of breast cancer (BRCA) patients. Samples obtained from TCGA and GEO databases were subjected to Weighted Gene Co
Autor:
Adriel Peng Guo Jun, Van T. Hoang, Duc M. Hoang, Hue T. H. Bui, Trung Quoc Bach, Anh Viet Bui, Anh T. L. Ngo, Liem Thanh Nguyen, Nhung T. H. Trinh, Hang M. Le
Publikováno v:
Journal of Cellular and Molecular Medicine
The interplay between mesenchymal stem/stromal cells (MSCs) and preservation conditions is critical to maintain the viability and functionality of these cells before administration. We observed that Ringer lactate (RL) maintained high viability of bo
Autor:
Bogdan Małkowski, Karolina Szewczyk-Golec, Jarosław Nuszkiewicz, Marta Pawłowska, Alina Woźniak, Marta Maruszak, Jolanta Czuczejko
Publikováno v:
Oxidative Medicine and Cellular Longevity
Oxidative Medicine and Cellular Longevity, Vol 2021 (2021)
Oxidative Medicine and Cellular Longevity, Vol 2021 (2021)
Lip, oral cavity, and pharyngeal cancers (LOCP) constitute a group of rare neoplasms with unfavorable prognosis. So far, not much is known about the role of vitamin D and oxidative stress in the pathogenesis of LOCP in the European population. The ai
Autor:
Cathy Vaillancourt, Márcia Rosângela Wink, Isadora Bertaco, Carla Zanatelli, Luiza Pretto, Thaís Casagrande Paim, Lucas Sagrillo-Fagundes
Publikováno v:
Journal of Cellular Physiology. 237:507-522
Purinergic signaling is a necessary mechanism to trigger or even amplify cell communication. Its ligands, notably adenosine triphosphate (ATP) and adenosine, modulate specific membrane-bound receptors in virtually all human cells. Regardless of the s
Autor:
Daniel J Stadtmauer, Günter P. Wagner
Publikováno v:
Biol Reprod
The decidua is a hallmark of reproduction in many placental mammals. Differentiation of decidual stromal cells is known to be induced by progesterone and the cyclic AMP/protein kinase A (cAMP/PKA) pathway. Several candidates have been identified as t
Autor:
Ravi C. Kalathur, SangJoon Lee, Thirumala-Devi Kanneganti, Lam Nhat Nguyen, Rajendra Karki, Yaqiu Wang
Publikováno v:
Nature. 597:415-419
Inflammasomes are important sentinels of innate immune defence, sensing pathogens and inducing cell death in infected cells1. There are several inflammasome sensors that each detect and respond to a specific pathogen- or damage-associated molecular p
Autor:
Shikun Yang, Aimei Li, Qin Liao, Hao Zhang, Li Zheng, Hailong Han, Jianwen Wang, Bin Yi, Zhaoxin Hu
Publikováno v:
Autophagy. 18:877-890
Diabetic nephropathy (DN) has become a major cause of end-stage renal disease, and autophagy disorder is implicated in the pathogenesis of DN. Our previous studies found that vitamin D (VD) and VDR (vitamin D receptor) played a renoprotective role by
Autor:
Linda Titus
Publikováno v:
Biology of Reproduction. 105:681-686
This review summarizes key findings from the US National Cancer Institute (NCI) diethylstilbestrol (DES) Combined Cohort Study with a focus on the results of the NCI Third Generation Study, a cohort of DES-exposed and -unexposed granddaughters. Findi