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Autor:
Dirk Strunk, Terry P Yamaguchi, Sandra Romero Marquez, Rouzanna Istvanffy, Michèle C. Buck, Jennifer Rivière, Katharina Brandstetter, Franziska Hettler, Matthias Kieslinger, Akiko Shimamura, Florian Bassermann, Mehmet Sacma, Hartmut Geiger, Erik Hameister, Jürgen Ruland, Christina Schreck, Heinrich Leonhardt, Theresa Landspersky, Robert A.J. Oostendorp, Judith S. Hecker, Kasiani C. Myers, Matthias Schiemann, Marilena Götz, Romina Ludwig, Martin Wolf, Katharina Götze
Publikováno v:
Blood
The cellular mechanisms required to ensure homeostasis of the hematopoietic niche and the ability of this niche to support hematopoiesis upon stress remain elusive. We here identify Wnt5a in Osterix+ mesenchymal progenitor and stem cells (MSPCs) as a
Autor:
Yoon Jeong Choi, Seok Jun Moon, Kim Euiseong, Sunil Dds. Kim, Ji Hyun Lee, Dong Min Shin, Dongzi Chen, Sukjoon Lee, Munsu Park
Publikováno v:
Journal of Endodontics. 48:240-248
Many studies have investigated the transcriptome profiles of dental stem cells for regenerative medicine. However, such studies use bulk RNA and do not consider cell-level heterogeneity. Here, we investigated the characteristics and heterogeneity of
Autor:
Jean-Paul Courneya, Rita Fishelevich, Irina G. Luzina, Violeta Rus, Sergei P. Atamas, Brian Hampton, Alexander V. Misharin, Nevins W. Todd, Virginia Lockatell, Tudor C. Badea, Horea Rus
Publikováno v:
American Journal of Respiratory Cell and Molecular Biology. 66:146-157
Some previous studies in tissue fibrosis have suggested a profibrotic contribution from elevated expression of a protein termed either Regulator of Cell Cycle (RGCC) or Response Gene to Complement 32 Protein (RGC-32). Our analysis of public gene expr
Autor:
Ji-Hye Seo, Young Joo Jeon
Publikováno v:
Journal of Microbiology and Biotechnology. 32:126-140
Stem cells can be applied usefully in basic research and clinical field due to their differentiation and self-renewal capacity. The aim of this study was to establish an effective novel therapeutic cellular source and create its molecular expression
Autor:
Ting-An Chou, Yi-Fang Huang, Chung-Yi Nien, Hsiang-Hsi Hong, Chao-Hua Liang, Adrienne Hong, Hui-Yi Hsiao, Tzung-Hai Yen, Alex Hong
Publikováno v:
Journal of Periodontology. 93:1553-1565
BACKGROUNDS Alveolar bone and cementum share many biological and developmental similarities. The mineralizing effect of calcitriol has been previously reported. Yet, its cementoinductivity has not been confirmed. This study evaluated the potential ce
Autor:
Lai Ling Tsang, Gang Li, Fuyuan Yang, Ye Chun Ruan, Zhihui Weng, Jiawei Huang, Tobias D Merson, Zeyuan Ji, Jiacheng Lin, Xiaohua Jiang, Chao Wan, Kin Pong U
Publikováno v:
Theranostics
Aims: Hypoxic-ischaemic encephalopathy (HIE) is one of the most serious complications in neonates and infants. Mesenchymal stromal cell (MSC)-based therapy is emerging as a promising treatment avenue for HIE. However, despite its enormous potential,
Autor:
Oscar Palomares, Alba Angelina, Beate Rückert, Mar Martín-Fontecha, Mario Pérez-Diego, Cezmi A. Akdis, Jacobo López-Abente, Ivan Nombela, Mübeccel Akdis
Publikováno v:
Mucosal Immunology
E-Prints Complutense. Archivo Institucional de la UCM
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E-Prints Complutense. Archivo Institucional de la UCM
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The generation of functional regulatory T cells (Tregs) is essential to keep tissue homeostasis and restore healthy immune responses in many biological and inflammatory contexts. Cannabinoids have been pointed out as potential therapeutic tools for s
Publikováno v:
American Journal of Orthodontics and Dentofacial Orthopedics. 161:e62-e71
Introduction Parathyroid hormone (PTH) potentiates the mechanical loading induced bone formation in fracture healing and orthodontics. This study aimed to gain insight into the underlying mechanisms in periodontal ligament fibroblasts (PDLFs). Method
Autor:
Lan Bai, Wen-Jie Zhao, Tengfei Ma, Manli Hu, Fengjiao Hu, Chongshu Jian, Han Tian, Xu Cheng, Jiajun Fu, Yanfang Zhang, Juan Yang, Zhi-Gang She, Yan-Xiao Ji, Junjie Zhou, Xiao-Jing Zhang, Peng Zhang, Yan Zhang, Jingwei Jiang, Hongliang Li
Publikováno v:
Hepatology. 75:403-418
Background & aims Although the prevalence of nonalcoholic fatty liver disease (NAFLD) has risen dramatically to 25% of the adult population worldwide, there are as yet no approved pharmacological interventions for the disease due to uncertainty about
Autor:
Maitha Aldokhayyil, Heather Grimm, Chenyi Ling, Michael F. Brown, Dulce H. Gomez, Marc D. Cook
Publikováno v:
Mediators of Inflammation, Vol 2021 (2021)
Mediators of Inflammation
Mediators of Inflammation
Background. C-reactive protein (CRP) is an independent biomarker of systemic inflammation and a predictor of future cardiovascular disease (CVD). More than just a pure bystander, CRP directly interacts with endothelial cells to decrease endothelial n