Zobrazeno 1 - 10
of 64
pro vyhledávání: '"ZHAO LI"'
Publikováno v:
Pancreas. 51:1411-1426
Background:We evaluated(1) the potential differentiation ability of bone mesenchymal stromal cells(BMSCs) into pancreatic lineage cells on rat acellular pancreatic bioscaffold (APB) and (2) the effect of differentiated BMSCs on chronic pancreatitis i
Autor:
Xiaofeng Lu, Qiuxiao Shi, Youmei Jin, Zhao Li, Jingqiu Cheng, Yanru Feng, Hao Yang, Tianshan She, Heng Li, Jie Chen, Ze Tao, Jie Fan
Publikováno v:
Journal of Controlled Release. 340:243-258
Immunotherapies based on immune checkpoint-blocking antibodies have been considered the most attractive cancer treatments in recent years. However, the systemic administration of immune checkpoint-blocking antibodies is limited by low response rates
Autor:
Ze Tao, Tianshan She, Yanru Feng, Shisheng Wang, Heng Li, Xiaofeng Lu, Yan Liang, Zhao Li, Jingqiu Cheng, Hao Yang, Jie Chen, Qiuxiao Shi
Publikováno v:
Theranostics
Chemotherapeutic multidrug resistance (MDR) is the major hindrance for clinical therapy of colorectal cancer (CRC). Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) with selective cytotoxicity might overcome MDR of CRC cells. Unfortuna
Publikováno v:
Bioengineered, Vol 12, Iss 1, Pp 6144-6154 (2021)
Bioengineered
article-version (VoR) Version of Record
Bioengineered
article-version (VoR) Version of Record
Abnormally high expression of RecQ protein-like 4 (RECQL4) has been observed in many cancers, including hepatocellular carcinoma (HCC). We aimed to explore the effects of RECQL4 on HCC progression and the possible mechanisms. RECQL4 expression in HCC
Autor:
Si-Qi Dong, Lian-Jing Cao, Tong-Min Wang, Pei-Fen Zhang, Wen-Qiong Xue, Jing-Wen Huang, Yong-Qiao He, Zi-Yi Wu, Xiao-Hui Zheng, Xi-Zhao Li, Wei Hua Jia, Da-Wei Yang, Jiang-Bo Zhang
Publikováno v:
Cancer Research and Treatment : Official Journal of Korean Cancer Association
Purpose Capecitabine is an extensively used oral prodrug of 5-fluorouracil in treatment of colon cancer and is known to cause hand-foot syndrome (HFS). As the target enzyme for capecitabine, thymidylate synthase (TYMS) plays a key role for 5-fluorour
Autor:
Pei-Fen Zhang, Wei Hua Jia, Xiao-Hui Zheng, Jiang-Bo Zhang, Li-Xia Lu, Ruo-Zheng Wang, Xi-Zhao Li, Ting Zhou
Publikováno v:
Cancer Science
The detection of Epstein‐Barr virus (EBV) DNA load in nasopharyngeal (NP) brushing samples for diagnosis of nasopharyngeal carcinoma (NPC) has attracted great attention. Further improvements that eliminate the need for clinical settings will greatl
Autor:
Changkun Zhang, Yang Wang, Qian Cheng, Xiao Xiang, Shi-Hua Hu, Siqi Wang, Zhao Li, Jiye Zhu, Xiaodong Xun
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 39, Iss 1, Pp 1-15 (2020)
Journal of Experimental & Clinical Cancer Research : CR
Journal of Experimental & Clinical Cancer Research : CR
Background The mechanism underlying sorafenib resistance in hepatocellular carcinoma (HCC) remains unclear. Accumulating evidence suggests that tumor-initiating cells (TICs) are a pivotal driving force. Both CD44 and Hedgehog signaling play crucial r
Publikováno v:
Chemical Communications. 56:3629-3632
We have developed a novel near-infrared ratiometric fluorescent theranostic nanoprobe. Upon reaction with glutathione, it releases a near-infrared fluorophore and chemotherapy drug. Notably, this nanoprobe can selectively kill HeLa and HepG-2 cancer
Autor:
Zhi Xing Fan, Jia Wang Ding, Di Liu, Yun Zhao Li, Jian Yang, Jing Zhang, Gang Zhou, Hui Wu, Jun Yang, Xin-An Wang
Publikováno v:
Nutrition, metabolism, and cardiovascular diseases : NMCD. 31(6)
Background and aims Myocardial ischemia/reperfusion injury (MI/RI) is a result of coronary revascularization, and often increases cell apoptosis and autophagy. Downregulated cellular FADD-like-IL-1β-converting enzyme-inhibitory protein (cFLIP) was a
Autor:
Xiao Lu Li, Xi Cheng Wang, Cui Xian Yang, Gui Mei Li, Min Xu, Yu Qi He, Zhao Li Ding, Xing Qi Dong, Jian Jian Li, Yong-Gang Yao, Hong Yi Zheng, Ren Rong Tian, Yong-Tang Zheng, Mi Zhang
Publikováno v:
Signal Transduction and Targeted Therapy
Signal Transduction and Targeted Therapy, Vol 5, Iss 1, Pp 1-12 (2020)
Signal Transduction and Targeted Therapy, Vol 5, Iss 1, Pp 1-12 (2020)
Understanding the processes of immune regulation in patients infected with the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is crucial for improving treatment. Here, we performed longitudinal whole-transcriptome RNA sequencing on peri