Zobrazeno 1 - 10
of 12
pro vyhledávání: '"929"'
Autor:
Jinsuk Kang
Publikováno v:
Cancer Research. 81:929-929
STAT3 functions are largely bifurcated: (1) STAT3 activated by Y705 phosphorylation (pY705) regulates target-gene expression in nucleus. (2) STAT3 activated by S727 phosphorylation (pS727) supports a electron transport complex (ETC) in mitochondria.
Autor:
Oscar Arrieta, R. Bernabé, Judith Dalmau, Miguel Angel Molina-Vila, Jorge Carrillo, Remedios Blanco, Teresa Moran, Clara Mayo de las Casas, Jillian Wilhelmina Paulina Bracht, Bonaventura Clotet, Christian Brander, Jordi Argilaguet, Julia G. Prado, Mariano Provencio, Javier Garcia-Corbacho, Ana Giménez-Capitán, Mónica Garzón, Erika Aldeguer, Andrés F. Cardona, Rafael Rosell, Bartomeu Massuti, Javier de Castro, Maria Gonzalez-Cao, Javier Martinez-Picado, Andreas Meyerhans, Sonia Rodríguez, Oscar Juan, Ana Drozdowskyj, Chung-Ying Huang, J. Blanco
Publikováno v:
Cancer Research. 80:929-929
Introduction: Treatment with anti PD-1/PD-L1 antibodies has demonstrated clinical activity in different types of solid tumors, but only 20 to 30% of patients (pts) respond to these immune checkpoint inhibitors (ICIs). Therefore, predictive biomarkers
Autor:
Max S. Wicha, Michael D. Brooks
Publikováno v:
Cancer Research. 77:929-929
The CSC hypothesis posits that there is a subset of tumors cells driving tumor growth and metastasis and that by targeting this population, tumors can be more efficiently eradicated. Recently it was shown that there are two types of CSCs in breast ca
Autor:
Timothy P. Kuka, Jason B. Bell, Branden S. Moriarity, Vincent W. Keng, David A. Largaespada, Barbara R. Tschida
Publikováno v:
Cancer Research. 74:929-929
The role of zinc finger and BTB domain containing 20 (ZBTB20) in hepatocellular carcinoma (HCC) is not well defined, as there are many discrepancies in the literature regarding its role in liver tumorigenesis. ZBTB20 has been implicated to play a rol
Autor:
Noopur Shah, Fang Liu, Hubert Maehr, Amanda K. Smolarek, Milan R. Uskokovic, Jae Young So, Nanjoo Suh
Publikováno v:
Cancer Research. 72:929-929
CD44, a transmembrane glycoprotein, is highly expressed in breast tumors, and the overexpression of CD44 has been associated with poor clinical outcome. CD44 has been known to play a key role in invasive growth of cancer by interacting with extracell
Autor:
Susanne M. Hooshmand, David C. Christiani, Xihong Lin, Rihong Zhai, Kofi Asomaning, Matthew H. Kulke, Chen-yu Liu, Zhaoxi Wang, Christine Frauenhoffer, Li Su, Monica Ter-Minassian
Publikováno v:
Cancer Research. 70:929-929
BACKGROUND: Genetic risk factors for sporadic neuroendocrine tumors remain poorly understood. To identify genetic variants associated with neuroendocrine tumor risk, we first performed a large-scale assessment of common genetic variants in candidate
Publikováno v:
Annales de biologie clinique. 75:431-441
The aim of the study is to investigate the clinical value of CEA (carcinoembryonic antigen) for detection of distant metastases (DM) in newly diagnosed breast cancer. This retrospective study focuses on a population of 929 patients with locally advan
Autor:
Chunping Zhu, Jie Pan, Ansheng Ling, Nonghua Lv, Xuqing Zhu, Xiuling Li, Chengxia Liu, Qi Feng, Jichang Li, Yuan Yuan, Xiaocui Yang, Baozhen Liu, Yiqi Du, Kaiguang Zhang, Yumei Li, Yingxia Hao, Yichao Feng, Jianfeng Zhou, Honghui Chen, Ping Xu, Qi Liu, Guoliang Ye, Zhao-Shen Li, Bo Lao, Liping Ye, Shengsheng Zhang, Rongzhou Li, Quan-Cai Cai, Mingquan Li, Zhiqiang Du
Publikováno v:
Gut
ObjectiveTo develop a gastric cancer (GC) risk prediction rule as an initial prescreening tool to identify individuals with a high risk prior to gastroscopy.DesignThis was a nationwide multicentre cross-sectional study. Individuals aged 40–80 years
Autor:
Limas Kupčinskas, Ilze Kikuste, Aija Linē, Undīne Rulle, Juozas Kupcinskas, Pawel Zayakin, Daiga Santare, I. Meistere, Angelina Pismennaja, Karīna Siliņa, Sergejs Isajevs, Hermann Brenner, Laimas Virginijus Jonaitis, Simone Werner, Zane Kalniņa, Chun Ying Wu, Marcis Leja
Publikováno v:
Cancer epidemiology, biomarkersprevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology. 26(10)
Background: Serum autoantibodies against tumor-associated antigens (TAAs) are detectable in early-stage gastric cancer patients; however, the time point during cancerogenesis when they appear in circulation is still obscure. Methods: In this study, w
Autor:
Shyamala C. Navada, Michael E. Petrone, Steven M. Fruchtman, John Roboz, Sool Yeon Cho, Lewis R. Silverman
Publikováno v:
Blood. 132:1357-1357
Introduction: CXCL12 (stromal cell derived factor-1, SDF-1), an 8 kDa peptide chemokine, ligates chemokine receptor 4 (CXCR4) and activates migration of normal and leukemic stem cells from the bone marrow into the blood. Rigosertib is a synthetic ben