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Autor:
Kai Aoki, Koki Yanazawa, Katsuyuki Tokinoya, Yasuhiro Shishikura, Kazuhiro Takekoshi, Seiko Ono, Takehito Sugasawa
Publikováno v:
Physiology International. 108:274-284
IntroductionExercise training is beneficial for reducing obesity. In particular, exercise training can lower the catecholamine concentration in circulation. Renalase, whose expression was first confirmed in the kidneys, is a physiologically active su
Autor:
Bruno Durante da Silva, Humberto Dellê, Gizele Alves Neves, Robson Luiz Bandoni, Fernanda Marciano Consolim-Colombo, Maria Helena Mattos Porter, Tercio Lemos de Moraes, Valentin A. Pavlov, Kátia De Angelis, Luis Ulloa, Pamela Nithzi Bricher Choque, Maria Claudia Irigoyen
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-13 (2021)
Scientific Reports
Scientific Reports
The mechanisms regulating immune cells recruitment into the heart during healing after an acute myocardial infarction (AMI) have major clinical implications. We investigated whether cholinergic stimulation with pyridostigmine, a cholinesterase inhibi
Autor:
Karl A. Nath, Vesna D. Garovic, James L. Kirkland, Sonja Suvakov, Reade A. Quinton, Meryl C. Nath, Santosh Parashuram, Fernando Sontag, Oscar Garcia-Valencia, Zvonimir S. Katusic, Livius V. d’Uscio, Joseph P. Grande, Yi Zhu, Mariam P. Alexander, Hajrunisa Cubro, Wendy M. White, Tamar Tchkonia, Natasa Milic, Tracey L. Weissgerber
Publikováno v:
Kidney Int
Preeclampsia is a pregnancy-specific hypertensive disorder characterized by proteinuria, and vascular injury in the second half of pregnancy. We hypothesized that endothelium-dependent vascular dysfunction is present in a murine model of preeclampsia
Publikováno v:
Endocrine, Metabolic & Immune Disorders - Drug Targets. 21:526-533
Background and Objective: All three isoforms of nitric oxide (NO) synthase (NOS) are targets for thyroid hormones in the cardiovascular system. The aim of this study was to assess the effects of hypo- and hyperthyroidism on inducible (iNOS), endothel
Autor:
Chakree Thongraung, Veerapol Kukongviriyapan, Akarachai Tubsakul, Ketmanee Senaphan, Gulladawan Jan-on, Poungrat Pakdeechote, Upa Kukongviriyapan, Weerapon Sangartit
Publikováno v:
Asian Pacific Journal of Tropical Biomedicine, Vol 11, Iss 1, Pp 10-19 (2021)
Objective: To evaluate the potential therapeutic effect of Sang-Yod rice bran hydrolysates (SRH) and in combination with lisinopril against hypertension, endothelial dysfunction, vascular remodeling, and oxidative stress in rats with nitric oxide def
Publikováno v:
International Journal of Medical Sciences
Pathological cutaneous scars, with aberrant extracellular matrix accumulation, have multiple origins. Antihypertensive medications, such as calcium channel blockers, have been used to treat pathological scars. However, a relationship between angioten
Autor:
Mohammed M. Alanazi, Ali Alhoshani, Naif O. Al-Harbi, Wael A. Alanazi, Abdullah F. Alasmari, Nemat Ali, Faisal Imam, Fawaz Alasmari, Mushtaq A. Ansari
Publikováno v:
Clinical and Experimental Pharmacology and Physiology. 48:478-489
Cardiovascular disease is a leading cause of death in diabetic patients. Hyperglycaemia and iatrogenic hypoglycaemia exacerbate several pathogenic mechanisms underlying hypertension and heart diseases. Carnitine is a potent endogenous antioxidant and
Publikováno v:
Clinical and Experimental Pharmacology and Physiology. 48:211-220
Metabolic syndrome (MetS) increases the risk of kidney disease. In SHRSP.Z-Leprfa /IzmDmcr (SHRSP.ZF) rats with MetS, protease-activated receptor 2 (PAR2)-mediated vasorelaxation is preserved in the aorta at 20 weeks of age (weeks) via enhancement of
Publikováno v:
Journal of Proteome Research. 19:4114-4124
The brainstem, the core of the central nervous system, plays a vital role in controlling arterial blood pressure and its elevation of hypertension subtypes, especially essential hypertension. Integrative metabolic and proteomic profiling was performe
Autor:
Temitayo Olabisi Ajibade, Idayat Titilayo Gbadamosi, N.A. Okolo, T.O. Omobowale, Ademola Adetokunbo Oyagbemi
Publikováno v:
Ife Journal of Science. 22:237-249
Hypertension is an important risk factor for cardiovascular diseases, which are major causes of mortality globally. This study evaluated the antihypertensive effects of Harungana madagascariensis on sodium fluorideinduced hypertension. Twenty-five ra