Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Fritsche, Lars"'
Autor:
Salvatore M; Department of Epidemiology, University of Michigan, Ann Arbor, MI 48109-2029, United States.; Center for Precision Health Data Science, Department of Biostatistics, University of Michigan, Ann Arbor, MI 48109-2029, United States., Kundu R; Center for Precision Health Data Science, Department of Biostatistics, University of Michigan, Ann Arbor, MI 48109-2029, United States.; Department of Biostatistics, University of Michigan, Ann Arbor, MI 48109-2029, United States., Shi X; Department of Biostatistics, University of Michigan, Ann Arbor, MI 48109-2029, United States., Friese CR; Rogel Cancer Center, Michigan Medicine, University of Michigan, Ann Arbor, MI 48109-2029, United States.; Center for Improving Patient and Population Health, School of Nursing, University of Michigan, Ann Arbor, MI 48109-2029, United States.; Department of Health Management and Policy, University of Michigan, Ann Arbor, MI 48109-2029, United States., Lee S; Department of Biostatistics, University of Michigan, Ann Arbor, MI 48109-2029, United States.; Graduate School of Data Science, Seoul National University, Gwanak-gu, Seoul, Republic of Korea., Fritsche LG; Center for Precision Health Data Science, Department of Biostatistics, University of Michigan, Ann Arbor, MI 48109-2029, United States.; Department of Biostatistics, University of Michigan, Ann Arbor, MI 48109-2029, United States.; Rogel Cancer Center, Michigan Medicine, University of Michigan, Ann Arbor, MI 48109-2029, United States., Mondul AM; Department of Epidemiology, University of Michigan, Ann Arbor, MI 48109-2029, United States.; Rogel Cancer Center, Michigan Medicine, University of Michigan, Ann Arbor, MI 48109-2029, United States., Hanauer D; Department of Learning Health Sciences, University of Michigan Medical School, Ann Arbor, MI 48109-2054, United States., Pearce CL; Department of Epidemiology, University of Michigan, Ann Arbor, MI 48109-2029, United States.; Rogel Cancer Center, Michigan Medicine, University of Michigan, Ann Arbor, MI 48109-2029, United States., Mukherjee B; Department of Epidemiology, University of Michigan, Ann Arbor, MI 48109-2029, United States.; Center for Precision Health Data Science, Department of Biostatistics, University of Michigan, Ann Arbor, MI 48109-2029, United States.; Department of Biostatistics, University of Michigan, Ann Arbor, MI 48109-2029, United States.
Publikováno v:
Journal of the American Medical Informatics Association : JAMIA [J Am Med Inform Assoc] 2024 Jun 20; Vol. 31 (7), pp. 1479-1492.
Autor:
Dutta D; Center for Statistical Genetics, University of Michigan, Ann Arbor, MI 48109, USA; Department of Biostatistics, University of Michigan, Ann Arbor, MI 48109, USA; Department of Biostatistics, Johns Hopkins University, Baltimore, MD 21205, USA., VandeHaar P; Center for Statistical Genetics, University of Michigan, Ann Arbor, MI 48109, USA; Department of Biostatistics, University of Michigan, Ann Arbor, MI 48109, USA., Fritsche LG; Center for Statistical Genetics, University of Michigan, Ann Arbor, MI 48109, USA; Department of Biostatistics, University of Michigan, Ann Arbor, MI 48109, USA., Zöllner S; Center for Statistical Genetics, University of Michigan, Ann Arbor, MI 48109, USA; Department of Biostatistics, University of Michigan, Ann Arbor, MI 48109, USA., Boehnke M; Center for Statistical Genetics, University of Michigan, Ann Arbor, MI 48109, USA; Department of Biostatistics, University of Michigan, Ann Arbor, MI 48109, USA., Scott LJ; Center for Statistical Genetics, University of Michigan, Ann Arbor, MI 48109, USA; Department of Biostatistics, University of Michigan, Ann Arbor, MI 48109, USA., Lee S; Center for Statistical Genetics, University of Michigan, Ann Arbor, MI 48109, USA; Department of Biostatistics, University of Michigan, Ann Arbor, MI 48109, USA; Graduate School of Data Science, Seoul National University, Seoul 08826, Republic of Korea. Electronic address: lee7801@snu.ac.kr.
Publikováno v:
American journal of human genetics [Am J Hum Genet] 2021 Apr 01; Vol. 108 (4), pp. 669-681. Date of Electronic Publication: 2021 Mar 16.
Autor:
Fritsche LG; Department of Biostatistics, University of Michigan School of Public Health, Ann Arbor, MI 48109, USA; Center for Statistical Genetics, University of Michigan School of Public Health, Ann Arbor, MI 48109, USA; Center for Precision Health Data Science, University of Michigan School of Public Health, Ann Arbor, MI 48109, USA; University of Michigan Rogel Cancer Center, University of Michigan, Ann Arbor, MI 48109, USA. Electronic address: larsf@umich.edu., Patil S; Department of Biostatistics, University of Michigan School of Public Health, Ann Arbor, MI 48109, USA; Center for Statistical Genetics, University of Michigan School of Public Health, Ann Arbor, MI 48109, USA., Beesley LJ; Department of Biostatistics, University of Michigan School of Public Health, Ann Arbor, MI 48109, USA; Center for Precision Health Data Science, University of Michigan School of Public Health, Ann Arbor, MI 48109, USA., VandeHaar P; Department of Biostatistics, University of Michigan School of Public Health, Ann Arbor, MI 48109, USA; Center for Statistical Genetics, University of Michigan School of Public Health, Ann Arbor, MI 48109, USA., Salvatore M; Department of Biostatistics, University of Michigan School of Public Health, Ann Arbor, MI 48109, USA; Center for Precision Health Data Science, University of Michigan School of Public Health, Ann Arbor, MI 48109, USA., Ma Y; Department of Biostatistics, University of Michigan School of Public Health, Ann Arbor, MI 48109, USA; Center for Statistical Genetics, University of Michigan School of Public Health, Ann Arbor, MI 48109, USA., Peng RB; Department of Biostatistics, University of Michigan School of Public Health, Ann Arbor, MI 48109, USA; Center for Precision Health Data Science, University of Michigan School of Public Health, Ann Arbor, MI 48109, USA; Department of Statistics, Northwestern University, Evanston, IL 60208, USA., Taliun D; Department of Biostatistics, University of Michigan School of Public Health, Ann Arbor, MI 48109, USA; Center for Statistical Genetics, University of Michigan School of Public Health, Ann Arbor, MI 48109, USA., Zhou X; Department of Biostatistics, University of Michigan School of Public Health, Ann Arbor, MI 48109, USA; Center for Statistical Genetics, University of Michigan School of Public Health, Ann Arbor, MI 48109, USA; Center for Precision Health Data Science, University of Michigan School of Public Health, Ann Arbor, MI 48109, USA., Mukherjee B; Department of Biostatistics, University of Michigan School of Public Health, Ann Arbor, MI 48109, USA; Center for Statistical Genetics, University of Michigan School of Public Health, Ann Arbor, MI 48109, USA; Center for Precision Health Data Science, University of Michigan School of Public Health, Ann Arbor, MI 48109, USA; Michigan Institute for Data Science, University of Michigan, Ann Arbor, MI 48109, USA; Department of Epidemiology, University of Michigan School of Public Health, Ann Arbor, MI 48109, USA; University of Michigan Rogel Cancer Center, University of Michigan, Ann Arbor, MI 48109, USA. Electronic address: bhramar@umich.edu.
Publikováno v:
American journal of human genetics [Am J Hum Genet] 2020 Nov 05; Vol. 107 (5), pp. 815-836. Date of Electronic Publication: 2020 Sep 28.
Autor:
Zhou W; Center for Statistical Genetics, University of Michigan School of Public Health, Ann Arbor, MI, USA. wzhou@broadinstitute.org.; Analytic and Translational Genetics Unit, Massachusetts General Hospital, Boston, MA, USA. wzhou@broadinstitute.org.; Program in Medical and Population Genetics, Broad Institute of Harvard and MIT, Cambridge, MA, USA. wzhou@broadinstitute.org.; Stanley Center for Psychiatric Research, Broad Institute of Harvard and MIT, Cambridge, MA, USA. wzhou@broadinstitute.org., Zhao Z; Center for Statistical Genetics, University of Michigan School of Public Health, Ann Arbor, MI, USA.; Department of Biostatistics, University of Michigan School of Public Health, Ann Arbor, MI, USA., Nielsen JB; Division of Cardiology, Department of Internal Medicine, University of Michigan Medical School, Ann Arbor, MI, USA., Fritsche LG; Center for Statistical Genetics, University of Michigan School of Public Health, Ann Arbor, MI, USA.; Department of Biostatistics, University of Michigan School of Public Health, Ann Arbor, MI, USA., LeFaive J; Center for Statistical Genetics, University of Michigan School of Public Health, Ann Arbor, MI, USA.; Department of Biostatistics, University of Michigan School of Public Health, Ann Arbor, MI, USA., Gagliano Taliun SA; Center for Statistical Genetics, University of Michigan School of Public Health, Ann Arbor, MI, USA.; Department of Biostatistics, University of Michigan School of Public Health, Ann Arbor, MI, USA., Bi W; Center for Statistical Genetics, University of Michigan School of Public Health, Ann Arbor, MI, USA.; Department of Biostatistics, University of Michigan School of Public Health, Ann Arbor, MI, USA., Gabrielsen ME; K.G. Jebsen Center for Genetic Epidemiology, Department of Public Health and Nursing, Norwegian University of Science and Technology (NTNU), Trondheim, Norway., Daly MJ; Analytic and Translational Genetics Unit, Massachusetts General Hospital, Boston, MA, USA.; Program in Medical and Population Genetics, Broad Institute of Harvard and MIT, Cambridge, MA, USA.; Stanley Center for Psychiatric Research, Broad Institute of Harvard and MIT, Cambridge, MA, USA.; Institute for Molecular Medicine Finland, Helsinki Institute of Life Sciences, University of Helsinki, Helsinki, Finland., Neale BM; Analytic and Translational Genetics Unit, Massachusetts General Hospital, Boston, MA, USA.; Program in Medical and Population Genetics, Broad Institute of Harvard and MIT, Cambridge, MA, USA.; Stanley Center for Psychiatric Research, Broad Institute of Harvard and MIT, Cambridge, MA, USA., Hveem K; K.G. Jebsen Center for Genetic Epidemiology, Department of Public Health and Nursing, Norwegian University of Science and Technology (NTNU), Trondheim, Norway.; HUNT Research Centre, Department of Public Health and Nursing, Norwegian University of Science and Technology (NTNU), Levanger, Norway., Abecasis GR; Center for Statistical Genetics, University of Michigan School of Public Health, Ann Arbor, MI, USA.; Department of Biostatistics, University of Michigan School of Public Health, Ann Arbor, MI, USA., Willer CJ; Division of Cardiology, Department of Internal Medicine, University of Michigan Medical School, Ann Arbor, MI, USA.; Department of Computational Medicine and Bioinformatics, University of Michigan, Ann Arbor, MI, USA.; Department of Human Genetics, University of Michigan Medical School, Ann Arbor, MI, USA., Lee S; Center for Statistical Genetics, University of Michigan School of Public Health, Ann Arbor, MI, USA. leeshawn@umich.edu.; Department of Biostatistics, University of Michigan School of Public Health, Ann Arbor, MI, USA. leeshawn@umich.edu.; Graduate School of Data Science, Seoul National University, Seoul, Republic of Korea. leeshawn@umich.edu.
Publikováno v:
Nature genetics [Nat Genet] 2020 Jun; Vol. 52 (6), pp. 634-639. Date of Electronic Publication: 2020 May 18.
Autor:
Beesley LJ; Department of Biostatistics, University of Michigan, Ann Arbor, Michigan., Salvatore M; Department of Biostatistics, University of Michigan, Ann Arbor, Michigan., Fritsche LG; Department of Biostatistics, University of Michigan, Ann Arbor, Michigan., Pandit A; Department of Biostatistics, University of Michigan, Ann Arbor, Michigan., Rao A; Department of Computational Medicine and Bioinformatics, University of Michigan, Ann Arbor, Michigan., Brummett C; Department of Anesthesiology, University of Michigan, Ann Arbor, Michigan., Willer CJ; Department of Computational Medicine and Bioinformatics, University of Michigan, Ann Arbor, Michigan., Lisabeth LD; Department of Epidemiology, University of Michigan, Ann Arbor, Michigan., Mukherjee B; Department of Biostatistics, University of Michigan, Ann Arbor, Michigan.
Publikováno v:
Statistics in medicine [Stat Med] 2020 Mar 15; Vol. 39 (6), pp. 773-800. Date of Electronic Publication: 2019 Dec 20.
Autor:
Zhao Z; Department of Biostatistics, University of Michigan School of Public Health, Ann Arbor, MI 48109, USA; Center for Statistical Genetics, University of Michigan School of Public Health, Ann Arbor, MI 48109, USA., Bi W; Department of Biostatistics, University of Michigan School of Public Health, Ann Arbor, MI 48109, USA; Center for Statistical Genetics, University of Michigan School of Public Health, Ann Arbor, MI 48109, USA., Zhou W; Analytic and Translational Genetics Unit, Massachusetts General Hospital, Boston, MA 02114, USA; Program in Medical and Population Genetics, Broad Institute of Harvard and MIT, Cambridge, MA 02142, USA; Stanley Center for Psychiatric Research, Broad Institute of Harvard and MIT, Cambridge, MA 02142, USA., VandeHaar P; Department of Biostatistics, University of Michigan School of Public Health, Ann Arbor, MI 48109, USA; Center for Statistical Genetics, University of Michigan School of Public Health, Ann Arbor, MI 48109, USA., Fritsche LG; Department of Biostatistics, University of Michigan School of Public Health, Ann Arbor, MI 48109, USA; Center for Statistical Genetics, University of Michigan School of Public Health, Ann Arbor, MI 48109, USA., Lee S; Department of Biostatistics, University of Michigan School of Public Health, Ann Arbor, MI 48109, USA; Center for Statistical Genetics, University of Michigan School of Public Health, Ann Arbor, MI 48109, USA. Electronic address: leeshawn@umich.edu.
Publikováno v:
American journal of human genetics [Am J Hum Genet] 2020 Jan 02; Vol. 106 (1), pp. 3-12. Date of Electronic Publication: 2019 Dec 19.
Autor:
Bi W; Department of Biostatistics, University of Michigan, Ann Arbor, MI 48109, USA; Center for Statistical Genetics, University of Michigan, Ann Arbor, MI 48109, USA., Zhao Z; Department of Biostatistics, University of Michigan, Ann Arbor, MI 48109, USA; Center for Statistical Genetics, University of Michigan, Ann Arbor, MI 48109, USA., Dey R; Department of Biostatistics, University of Michigan, Ann Arbor, MI 48109, USA; Center for Statistical Genetics, University of Michigan, Ann Arbor, MI 48109, USA; Department of Biostatistics, Harvard T. H. Chan School of Public Health, Boston, MA 02115, USA., Fritsche LG; Department of Biostatistics, University of Michigan, Ann Arbor, MI 48109, USA; Center for Statistical Genetics, University of Michigan, Ann Arbor, MI 48109, USA., Mukherjee B; Department of Biostatistics, University of Michigan, Ann Arbor, MI 48109, USA., Lee S; Department of Biostatistics, University of Michigan, Ann Arbor, MI 48109, USA; Center for Statistical Genetics, University of Michigan, Ann Arbor, MI 48109, USA. Electronic address: leeshawn@umich.edu.
Publikováno v:
American journal of human genetics [Am J Hum Genet] 2019 Dec 05; Vol. 105 (6), pp. 1182-1192. Date of Electronic Publication: 2019 Nov 14.
Autor:
Dey R; Department of Biostatistics and Center for Statistical Genetics, University of Michigan School of Public Health, Ann Arbor, Michigan., Nielsen JB; Department of Epidemiology Research, Statens Serum Institut, Copenhagen, Denmark., Fritsche LG; Department of Biostatistics and Center for Statistical Genetics, University of Michigan School of Public Health, Ann Arbor, Michigan., Zhou W; Department of Computational Medicine and Bioinformatics, University of Michigan, Ann Arbor, Michigan., Zhu H; Department of Mathematical Sciences, Michigan Technological University, Houghton, Michigan., Willer CJ; Department of Computational Medicine and Bioinformatics, University of Michigan, Ann Arbor, Michigan.; Department of Internal Medicine, Division of Cardiovascular Medicine, University of Michigan, Ann Arbor, Michigan.; Department of Human Genetics, University of Michigan, Ann Arbor, Michigan., Lee S; Department of Biostatistics and Center for Statistical Genetics, University of Michigan School of Public Health, Ann Arbor, Michigan.
Publikováno v:
Genetic epidemiology [Genet Epidemiol] 2019 Jul; Vol. 43 (5), pp. 462-476. Date of Electronic Publication: 2019 Feb 22.
Loss-of-function genomic variants highlight potential therapeutic targets for cardiovascular disease
Autor:
Nielsen, Jonas B, Rom, Oren, Surakka, Ida, Graham, Sarah E, Zhou, Wei, Roychowdhury, Tanmoy, Fritsche, Lars G, Gagliano Taliun, Sarah A, Sidore, Carlo, Liu, Yuhao, Gabrielsen, Maiken E, Skogholt, Anne Heidi, Wolford, Brooke, Overton, William, Zhao, Ying, Chen, Jin, Zhang, He, Hornsby, Whitney E, Acheampong, Akua, Grooms, Austen, Schaefer, Amanda, Zajac, Gregory JM, Villacorta, Luis, Zhang, Jifeng, Brumpton, Ben, Løset, Mari, Rai, Vivek, Lundegaard, Pia R, Olesen, Morten S, Taylor, Kent D, Palmer, Nicholette D, Chen, Yii-Der, Choi, Seung H, Lubitz, Steven A, Ellinor, Patrick T, Barnes, Kathleen C, Daya, Michelle, Rafaels, Nicholas, Weiss, Scott T, Lasky-Su, Jessica, Tracy, Russell P, Vasan, Ramachandran S, Cupples, L Adrienne, Mathias, Rasika A, Yanek, Lisa R, Becker, Lewis C, Peyser, Patricia A, Bielak, Lawrence F, Smith, Jennifer A, Aslibekyan, Stella, Hidalgo, Bertha A, Arnett, Donna K, Irvin, Marguerite R, Wilson, James G, Musani, Solomon K, Correa, Adolfo, Rich, Stephen S, Guo, Xiuqing, Rotter, Jerome I, Konkle, Barbara A, Johnsen, Jill M, Ashley-Koch, Allison E, Telen, Marilyn J, Sheehan, Vivien A, Blangero, John, Curran, Joanne E, Peralta, Juan M, Montgomery, Courtney, Sheu, Wayne H-H, Chung, Ren-Hua, Schwander, Karen, Nouraie, Seyed M, Gordeuk, Victor R, Zhang, Yingze, Kooperberg, Charles, Reiner, Alexander P, Jackson, Rebecca D, Bleecker, Eugene R, Meyers, Deborah A, Li, Xingnan, Das, Sayantan, Yu, Ketian, LeFaive, Jonathon, Smith, Albert, Blackwell, Tom, Taliun, Daniel, Zollner, Sebastian, Forer, Lukas, Schoenherr, Sebastian, Fuchsberger, Christian, Pandit, Anita, Zawistowski, Matthew, Kheterpal, Sachin, Brummett, Chad M, Natarajan, Pradeep, Schlessinger, David, Lee, Seunggeun, Kang, Hyun Min, Cucca, Francesco, Holmen, Oddgeir L
Publikováno v:
Nature communications, vol 11, iss 1
Pharmaceutical drugs targeting dyslipidemia and cardiovascular disease (CVD) may increase the risk of fatty liver disease and other metabolic disorders. To identify potential novel CVD drug targets without these adverse effects, we perform genome-wid
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::5d0f980fbe0d617bd1e47bd91d18febe
https://escholarship.org/uc/item/4fx41254
https://escholarship.org/uc/item/4fx41254