Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Thomas Girke"'
Autor:
Paul Shannon, Kasper D. Hansen, Sean Davis, Vincent J. Carey, Benilton S. Carvalho, Marc R. J. Carlson, Thomas Girke, Valerie Obenchain, Martin Morgan, Raphael Gottardo, Rafael A. Irizarry, Dan Tenenbaum, Hervé Pagès, Héctor Corrada Bravo, Alejandro Reyes, Michael I. Love, Robert Gentleman, James W. MacDonald, Simon Anders, Florian Hahne, Levi Waldron, Andrzej K. Oleś, Wolfgang Huber, Michael S. Lawrence, Gordon K. Smyth, Laurent Gatto
Publikováno v:
Nature Methods
Nature methods, Vol. 12, no.2, p. 115-21 (2015)
Nature methods, Vol. 12, no.2, p. 115-21 (2015)
Bioconductor is an open-source, open-development software project for the analysis and comprehension of high-throughput data in genomics and molecular biology. The project aims to enable interdisciplinary research, collaboration and rapid development
Autor:
Jing Hua Zhao, Hyung Jin Choi, Leslie J. Baier, Vilmundur Gudnason, Melina Claussnitzer, Jian Shen, Mary F. Feitosa, Melissa E. Garcia, Douglas P. Kiel, Murielle Bochud, Christian Gieger, L. B. Husted, Kristina Åkesson, Alan Hubbard, John-Olov Jansson, Jacqueline S. L. Kloth, Yanhua Zhou, Richard L. Prince, Angela Döring, H.-Erich Wichmann, Thomas Girke, Monica J. Hubal, Mark A. Tarnopolsky, Laura M. Yerges-Armstrong, Yi-Hsiang Hsu, Patricia A. Thompson, Mattias Lorentzon, Gudmar Thorleifsson, Wen-Chi Chou, Karin M. A. Swart, Tim D. Spector, Braxton D. Mitchell, Kim M. Huffman, Inês Barroso, Igor Rudan, William E. Kraus, Nicholas J. Wareham, Chan Soo Shin, Jaakko Tuomilehto, Gunnar Sigurdsson, Bok Ghee Han, Munro Peacock, Mao Fu, Unnur Thorsteinsdottir, Gregory Livshits, Laura J. Scott, Jane A. Cauley, Heikki A. Koistinen, Arjun Verma, Peggy M. Cawthon, Carrie M. Nielson, Aron S. Buchman, Aarno Palotie, Daniel S. Evans, Elisabeth Widen, Caroline Hayward, Frances M K Williams, Nam H. Cho, Peter Vollenweider, Liisa Byberg, Robert Luben, Veikko Salomaa, Alena Stančáková, Markus M. Lerch, Jian'an Luan, Eric P. Hoffman, Thomas Lang, Jari Lahti, Mike Erdos, Stephen C. J. Parker, Ida Malkin, Jaspal S. Kooner, Francis S. Collins, Claes Ohlsson, James F. Wilson, Ben A. Oostra, Carolina Medina-Gomez, Toby Johnson, Cornelia M. van Duijn, Joel Eriksson, Natalia Campos Obanda, Samuli Ripatti, Kay-Tee Khaw, Ryan P. Welch, Jeffrey R. O'Connell, Karl Michaëlsson, Erik Ingelsson, Elizabeth A. Streeten, Eric E. Schadt, Markus Perola, Albert V. Smith, Henna Cederberg, Ruth J. F. Loos, Michael J. Econs, Thomas Illig, Ingrid B. Borecki, Unnur Styrkarsdottir, Kari Stefansson, Anne B. Newman, Ozren Polasek, Weihua Zhang, Shad B. Smith, Wen Chi Hsueh, Serkalem Demissie, Najaf Amin, Simon Melov, Lenore J. Launer, Harald Grallert, E. Steinhagen-Thiessen, Jean Wactawski-Wende, Stuart H. Ralston, Leif Mosekilde, Liesbeth Vandenput, Zoltán Kutalik, Nicole L. Glazer, Teemu Kuulasmaa, Lisette Stolk, Johanna Kuusisto, Lei Yu, Steven R. Cummings, Cynthia A. Thomson, Harry Campbell, Mark Walker, Lars Lind, André G. Uitterlinden, Albert Hofman, Linda Broer, Vicky Ossowski, John C. Chambers, Jerome I. Rotter, Gregory J. Tranah, Östen Ljunggren, Tamara B. Harris, Ali A. Aghdassi, Nicole Soranzo, Jong-Young Lee, Bruce M. Psaty, Magnus Karlsson, Luda Diatchenko, Nicole C. Wright, A.W. Enneman, Cecilia M. Lindgren, Yongmei Liu, Sabine Schipf, Tian Liu, Annette Peters, Daniel L. Koller, Georg Homuth, Ilja Demuth, Andrew P. Morris, Jagvir Grewal, Katri Räikkönen, Markku Laakso, Tuomas O. Kilpeläinen, Michael Boehnke, Fernando Rivadeneira, David A. Bennett, Joban Sehmi, Gudny Eiriksdottir, Rainer Biffar, Till Ittermann, Natasja M. van Schoor, Michael N. Weedon, Zhao Chen, Norman Klopp, Antti Jula, Bente L. Langdahl, William Maixner, Håkan Melhus, Rosalie A. M. Dhonukshe-Rutten, Dan Mellström, Robert L. Hanson, M. Carola Zillikens, Janina S. Ried, David Karasik, Suzanne Satterfield, Stephen B. Kritchevsky, Henry Völzke, Karol Estrada, Thomas Meitinger, Sian Tsung Tan, John A Robbins, Dawn M. Waterworth, Lars Bertram, Fiona E. McGuigan, Philip L. De Jager, Youfang Liu, Emmi Tikkanen, Eric S. Orwoll, Weijia Xie, Joanne M. Jordan, Johan G. Eriksson, Joshua R. Lewis
Publikováno v:
Nature Communications
Nature Communications, 8(1)
Zillikens, M C, Demissie, S, Hsu, Y H, Yerges-Armstrong, L M, Chou, W C, Stolk, L, Livshits, G, Broer, L, Johnson, T, Koller, D L, Kutalik, Z, Luan, J, Malkin, I, Ried, J S, Smith, A V, Thorleifsson, G, Vandenput, L, Hua Zhao, J, Zhang, W, Aghdassi, A, Åkesson, K, Amin, N, Baier, L J, Barroso, I, Bennett, D A, Bertram, L, Biffar, R, Bochud, M, Boehnke, M, Borecki, I B, Buchman, A S, Byberg, L, Campbell, H, Campos Obanda, N, Cauley, J A, Cawthon, P M, Cederberg, H, Chen, Z, Cho, N H, Jin Choi, H, Claussnitzer, M, Collins, F S, Cummings, S R, De Jager, P L, Demuth, I, Dhonukshe-Rutten, R A M, DIatchenko, L, Eiriksdottir, G, Enneman, A W, Erdos, M, Eriksson, J G, Eriksson, J, Estrada, K, Evans, D S, Feitosa, M F, Fu, M, Garcia, M E, Gieger, C, Girke, T, Glazer, N L, Grallert, H, Grewal, J, Han, B-G, Hanson, R L, Hayward, C, Hofman, A, Hoffman, E P, Homuth, G, Hsueh, W C, Hubal, M J, Hubbard, A, Huffman, K M, Husted, L B, Illig, T, Ingelsson, E, Ittermann, T, Jansson, J O, Jordan, J M, Jula, A, Karlsson, M, Khaw, K-T, Kilpelaïnen, T O, Klopp, N, Kloth, J S L, Koistinen, H A, Kraus, W E, Kritchevsky, S B, Kuulasmaa, T, Kuusisto, J, Laakso, M, Lahti, J, Lang, T F, Langdahl, B L, Launer, L J, Lee, J-Y, Lerch, M M, Lewis, J R, Lind, L, Lindgren, C M, Liu, Y, Liu, T, Liu, Y, Ljunggren, Ö, Lorentzon, M, Luben, R N, Maixner, W, McGuigan, F E, Medina-Gomez, C, Meitinger, T, Melhus, H, Mellström, D, Melov, S, Michaëlsson, K, Mitchell, B D, Morris, A P, Mosekilde, L, Newman, A B, Nielson, C M, O'Connell, J R, Oostra, B A, Orwoll, E S, Palotie, A, Parker, S, Peacock, M, Perola, M, Peters, A, Polasek, O, Prince, R L, Raïkkönen, K, Ralston, S H, Ripatti, S, Robbins, J A, Rotter, J I, Rudan, I, Salomaa, V, Satterfield, S, Schadt, E E, Schipf, S, Scott, L, Sehmi, J, Shen, J, Soo Shin, C, Sigurdsson, G, Smith, S, Soranzo, N, Stančáková, A, Steinhagen-Thiessen, E, Streeten, E A, Styrkarsdottir, U, Swart, K M A, Tan, S-T, Tarnopolsky, M A, Thompson, P, Thomson, C A, Thorsteinsdottir, U, Tikkanen, E, Tranah, G J, Tuomilehto, J, Van Schoor, N M, Verma, A, Vollenweider, P, Völzke, H, Wactawski-Wende, J, Walker, M J, Weedon, M N, Welch, R, Wichman, H E, Widen, E, Williams, F M K, Wilson, J F, Wright, N C, Xie, W, Yu, L, Zhou, Y, Chambers, J C, Döring, A, van Duijn, C M, Econs, M J, Gudnason, V, Kooner, J S, Psaty, B M, Spector, T D, Stefansson, K, Rivadeneira, F, Uitterlinden, A G, Wareham, N J, Ossowski, V, Waterworth, D, Loos, R J F, Karasik, D, Harris, T B, Ohlsson, C & Kiel, D P 2017, ' Large meta-analysis of genome-wide association studies identifies five loci for lean body mass ', Nature Communications, vol. 8, no. 1, 80 . https://doi.org/10.1038/s41467-017-00031-7
Nature Communications, Vol 8, Iss 1, Pp 1-13 (2017)
Nature Communications 8 (2017) 1
Nature Communications, 8:80. Nature Publishing Group
Zillikens, M C, Demissie, S, Hsu, Y-H, Yerges-Armstrong, L M, Chou, W-C, Stolk, L, Livshits, G, Broer, L, Johnson, T, Koller, D L, Kutalik, Z, Luan, J, Malkin, I, Ried, J S, Smith, A V, Thorleifsson, G, Vandenput, L, Hua Zhao, J, Zhang, W, Aghdassi, A, Åkesson, K, Amin, N, Baier, L J, Barroso, I, Bennett, D A, Bertram, L, Biffar, R, Bochud, M, Boehnke, M, Borecki, I B, Buchman, A S, Byberg, L, Campbell, H, Campos Obanda, N, Cauley, J A, Cawthon, P M, Cederberg, H, Chen, Z, Cho, N H, Jin Choi, H, Claussnitzer, M, Collins, F, Cummings, S R, De Jager, P L, Demuth, I, Dhonukshe-Rutten, R A M, Diatchenko, L, Eiriksdottir, G, Enneman, A W, Erdos, M, Eriksson, J G, Eriksson, J, Estrada, K, Evans, D S, Feitosa, M F, Fu, M, Garcia, M, Gieger, C, Girke, T, Glazer, N L, Grallert, H, Grewal, J, Han, B-G, Hanson, R L, Hayward, C, Hofman, A, Hoffman, E P, Homuth, G, Hsueh, W-C, Hubal, M J, Hubbard, A, Huffman, K M, Husted, L B, Illig, T, Ingelsson, E, Ittermann, T, Jansson, J-O, Jordan, J M, Jula, A, Karlsson, M, Khaw, K-T, Kilpeläinen, T O, Klopp, N, Kloth, J S L, Koistinen, H A, Kraus, W E, Kritchevsky, S, Kuulasmaa, T, Kuusisto, J, Laakso, M, Lahti, J, Lang, T, Langdahl, B L, Launer, L J, Lee, J-Y, Lerch, M M, Lewis, J R, Lind, L, Lindgren, C, Liu, Y, Liu, T, Liu, Y, Ljunggren, Ö, Lorentzon, M, Luben, R N, Maixner, W, McGuigan, F E, Medina-Gomez, C, Meitinger, T, Melhus, H, Mellström, D, Melov, S, Michaëlsson, K, Mitchell, B D, Morris, A P, Mosekilde, L, Newman, A, Nielson, C M, O'Connell, J R, Oostra, B A, Orwoll, E S, Palotie, A, Parker, S, Peacock, M, Perola, M, Peters, A, Polasek, O, Prince, R L, Räikkönen, K, Ralston, S H, Ripatti, S, Robbins, J A, Rotter, J I, Rudan, I, Salomaa, V, Satterfield, S, Schadt, E E, Schipf, S, Scott, L, Sehmi, J, Shen, J, Soo Shin, C, Sigurdsson, G, Smith, S, Soranzo, N, Stančáková, A, Steinhagen-Thiessen, E, Streeten, E A, Styrkarsdottir, U, Swart, K M A, Tan, S-T, Tarnopolsky, M A, Thompson, P, Thomson, C A, Thorsteinsdottir, U, Tikkanen, E, Tranah, G J, Tuomilehto, J, van Schoor, N M, Verma, A, Vollenweider, P, Völzke, H, Wactawski-Wende, J, Walker, M, Weedon, M N, Welch, R, Wichmann, H-E, Widen, E, Williams, F M K, Wilson, J F, Wright, N C, Xie, W, Yu, L, Zhou, Y, Chambers, J C, Döring, A, van Duijn, C M, Econs, M J, Gudnason, V, Kooner, J S, Psaty, B M, Spector, T D, Stefansson, K, Rivadeneira, F, Uitterlinden, A G, Wareham, N J, Ossowski, V, Waterworth, D, Loos, R J F, Karasik, D, Harris, T B, Ohlsson, C & Kiel, D P 2017, ' Large meta-analysis of genome-wide association studies identifies five loci for lean body mass ', Nature Communications, vol. 8, 80 . https://doi.org/10.1038/s41467-017-00031-7
Zillikens, M C, Demissie, S, Hsu, Y, Yerges-armstrong, L M, Chou, W, Stolk, L, Livshits, G, Broer, L, Johnson, T, Koller, D L, Kutalik, Z, Luan, J, Malkin, I, Ried, J S, Smith, A V, Thorleifsson, G, Vandenput, L, Hua Zhao, J, Zhang, W, Aghdassi, A, Åkesson, K, Amin, N, Baier, L J, Barroso, I, Bennett, D A, Bertram, L, Biffar, R, Bochud, M, Boehnke, M, Borecki, I B, Buchman, A S, Byberg, L, Campbell, H, Campos Obanda, N, Cauley, J A, Cawthon, P M, Cederberg, H, Chen, Z, Cho, N H, Jin Choi, H, Claussnitzer, M, Collins, F, Cummings, S R, De Jager, P L, Demuth, I, Dhonukshe-rutten, R A M, Diatchenko, L, Eiriksdottir, G, Enneman, A W, Erdos, M, Eriksson, J G, Eriksson, J, Estrada, K, Evans, D S, Feitosa, M F, Fu, M, Garcia, M, Gieger, C, Girke, T, Glazer, N L, Grallert, H, Grewal, J, Han, B, Hanson, R L, Hayward, C, Hofman, A, Hoffman, E P, Homuth, G, Hsueh, W, Hubal, M J, Hubbard, A, Huffman, K M, Husted, L B, Illig, T, Ingelsson, E, Ittermann, T, Jansson, J, Jordan, J M, Jula, A, Karlsson, M, Khaw, K, Kilpeläinen, T O, Klopp, N, Kloth, J S L, Koistinen, H A, Kraus, W E, Kritchevsky, S, Kuulasmaa, T, Kuusisto, J, Laakso, M, Lahti, J, Lang, T, Langdahl, B L, Launer, L J, Lee, J, Lerch, M M, Lewis, J R, Lind, L, Lindgren, C, Liu, Y, Liu, T, Liu, Y, Ljunggren, Ö, Lorentzon, M, Luben, R N, Maixner, W, Mcguigan, F E, Medina-gomez, C, Meitinger, T, Melhus, H, Mellström, D, Melov, S, Michaëlsson, K, Mitchell, B D, Morris, A P, Mosekilde, L, Newman, A, Nielson, C M, O’connell, J R, Oostra, B A, Orwoll, E S, Palotie, A, Parker, S, Peacock, M, Perola, M, Peters, A, Polasek, O, Prince, R L, Räikkönen, K, Ralston, S H, Ripatti, S, Robbins, J A, Rotter, J I, Rudan, I, Salomaa, V, Satterfield, S, Schadt, E E, Schipf, S, Scott, L, Sehmi, J, Shen, J, Soo Shin, C, Sigurdsson, G, Smith, S, Soranzo, N, Stančáková, A, Steinhagen-thiessen, E, Streeten, E A, Styrkarsdottir, U, Swart, K M A, Tan, S, Tarnopolsky, M A, Thompson, P, Thomson, C A, Thorsteinsdottir, U, Tikkanen, E, Tranah, G J, Tuomilehto, J, Van Schoor, N M, Verma, A, Vollenweider, P, Völzke, H, Wactawski-wende, J, Walker, M, Weedon, M N, Welch, R, Wichman, H, Widen, E, Williams, F M K, Wilson, J F, Wright, N C, Xie, W, Yu, L, Zhou, Y, Chambers, J C, Döring, A, Van Duijn, C M, Econs, M J, Gudnason, V, Kooner, J S, Psaty, B M, Spector, T D, Stefansson, K, Rivadeneira, F, Uitterlinden, A G, Wareham, N J, Ossowski, V, Waterworth, D, Loos, R J F, Karasik, D, Harris, T B, Ohlsson, C & Kiel, D P 2017, ' Large meta-analysis of genome-wide association studies identifies five loci for lean body mass ', Nature Communications, vol. 8, no. 1 . https://doi.org/10.1038/s41467-017-00031-7
Nature Communications, 8(1):80. Nature Publishing Group
Zillikens, M C, Demissie, S, Hsu, Y-H, Yerges-Armstrong, L M, Chou, W-C, Stolk, L, Livshits, G, Broer, L, Johnson, T, Koller, D L, Kutalik, Z, Luan, J, Malkin, I, Ried, J S, Smith, A V, Thorleifsson, G, Vandenput, L, Hua Zhao, J, Zhang, W, Aghdassi, A, Åkesson, K, Amin, N, Baier, L J, Barroso, I, Bennett, D A, Bertram, L, Biffar, R, Bochud, M, Boehnke, M, Borecki, I B, Buchman, A S, Byberg, L, Campbell, H, Campos Obanda, N, Cauley, J A, Cawthon, P M, Cederberg, H, Chen, Z, Cho, N H, Jin Choi, H, Claussnitzer, M, Collins, F, Cummings, S R, De Jager, P L, Demuth, I, Dhonukshe-Rutten, R A M, Diatchenko, L, Eiriksdottir, G, Enneman, A W, Erdos, M, Eriksson, J G, Eriksson, J, Estrada, K, Evans, D S, Feitosa, M F, Fu, M, Garcia, M, Gieger, C, Girke, T, Glazer, N L, Grallert, H, Grewal, J, Han, B-G, Hanson, R L, Hayward, C, Hofman, A, Hoffman, E P, Homuth, G, Hsueh, W-C, Hubal, M J, Hubbard, A, Huffman, K M, Husted, L B, Illig, T, Ingelsson, E, Ittermann, T, Jansson, J-O, Jordan, J M, Jula, A, Karlsson, M, Khaw, K-T, Kilpeläinen, T O, Klopp, N, Kloth, J S L, Koistinen, H A, Kraus, W E, Kritchevsky, S, Kuulasmaa, T, Kuusisto, J, Laakso, M, Lahti, J, Lang, T, Langdahl, B L, Launer, L J, Lee, J-Y, Lerch, M M, Lewis, J R, Lind, L, Lindgren, C, Liu, Y, Liu, T, Liu, Y, Ljunggren, Ö, Lorentzon, M, Luben, R N, Maixner, W, McGuigan, F E, Medina-Gomez, C, Meitinger, T, Melhus, H, Mellström, D, Melov, S, Michaëlsson, K, Mitchell, B D, Morris, A P, Mosekilde, L, Newman, A, Nielson, C M, O'Connell, J R, Oostra, B A, Orwoll, E S, Palotie, A, Parker, S C J, Peacock, M, Perola, M, Peters, A, Polasek, O, Prince, R L, Räikkönen, K, Ralston, S H, Ripatti, S, Robbins, J A, Rotter, J I, Rudan, I, Salomaa, V, Satterfield, S, Schadt, E E, Schipf, S, Scott, L, Sehmi, J, Shen, J, Soo Shin, C, Sigurdsson, G, Smith, S, Soranzo, N, Stančáková, A, Steinhagen-Thiessen, E, Streeten, E A, Styrkarsdottir, U, Swart, K M A, Tan, S-T, Tarnopolsky, M A, Thompson, P, Thomson, C A, Thorsteinsdottir, U, Tikkanen, E, Tranah, G J, Tuomilehto, J, van Schoor, N M, Verma, A, Vollenweider, P, Völzke, H, Wactawski-Wende, J, Walker, M, Weedon, M N, Welch, R, Wichmann, H-E, Widen, E, Williams, F M K, Wilson, J F, Wright, N C, Xie, W, Yu, L, Zhou, Y, Chambers, J C, Döring, A, van Duijn, C M, Econs, M J, Gudnason, V, Kooner, J S, Psaty, B M, Spector, T D, Stefansson, K, Rivadeneira, F, Uitterlinden, A G, Wareham, N J, Ossowski, V, Waterworth, D, Loos, R J F, Karasik, D, Harris, T B, Ohlsson, C & Kiel, D P 2017, ' Large meta-analysis of genome-wide association studies identifies five loci for lean body mass ', Nature Communications, vol. 8, no. 1, pp. 80 . https://doi.org/10.1038/s41467-017-00031-7
Nature communications, vol. 8, no. 1, pp. 80
Nature Communications, 8(1)
Zillikens, M C, Demissie, S, Hsu, Y H, Yerges-Armstrong, L M, Chou, W C, Stolk, L, Livshits, G, Broer, L, Johnson, T, Koller, D L, Kutalik, Z, Luan, J, Malkin, I, Ried, J S, Smith, A V, Thorleifsson, G, Vandenput, L, Hua Zhao, J, Zhang, W, Aghdassi, A, Åkesson, K, Amin, N, Baier, L J, Barroso, I, Bennett, D A, Bertram, L, Biffar, R, Bochud, M, Boehnke, M, Borecki, I B, Buchman, A S, Byberg, L, Campbell, H, Campos Obanda, N, Cauley, J A, Cawthon, P M, Cederberg, H, Chen, Z, Cho, N H, Jin Choi, H, Claussnitzer, M, Collins, F S, Cummings, S R, De Jager, P L, Demuth, I, Dhonukshe-Rutten, R A M, DIatchenko, L, Eiriksdottir, G, Enneman, A W, Erdos, M, Eriksson, J G, Eriksson, J, Estrada, K, Evans, D S, Feitosa, M F, Fu, M, Garcia, M E, Gieger, C, Girke, T, Glazer, N L, Grallert, H, Grewal, J, Han, B-G, Hanson, R L, Hayward, C, Hofman, A, Hoffman, E P, Homuth, G, Hsueh, W C, Hubal, M J, Hubbard, A, Huffman, K M, Husted, L B, Illig, T, Ingelsson, E, Ittermann, T, Jansson, J O, Jordan, J M, Jula, A, Karlsson, M, Khaw, K-T, Kilpelaïnen, T O, Klopp, N, Kloth, J S L, Koistinen, H A, Kraus, W E, Kritchevsky, S B, Kuulasmaa, T, Kuusisto, J, Laakso, M, Lahti, J, Lang, T F, Langdahl, B L, Launer, L J, Lee, J-Y, Lerch, M M, Lewis, J R, Lind, L, Lindgren, C M, Liu, Y, Liu, T, Liu, Y, Ljunggren, Ö, Lorentzon, M, Luben, R N, Maixner, W, McGuigan, F E, Medina-Gomez, C, Meitinger, T, Melhus, H, Mellström, D, Melov, S, Michaëlsson, K, Mitchell, B D, Morris, A P, Mosekilde, L, Newman, A B, Nielson, C M, O'Connell, J R, Oostra, B A, Orwoll, E S, Palotie, A, Parker, S, Peacock, M, Perola, M, Peters, A, Polasek, O, Prince, R L, Raïkkönen, K, Ralston, S H, Ripatti, S, Robbins, J A, Rotter, J I, Rudan, I, Salomaa, V, Satterfield, S, Schadt, E E, Schipf, S, Scott, L, Sehmi, J, Shen, J, Soo Shin, C, Sigurdsson, G, Smith, S, Soranzo, N, Stančáková, A, Steinhagen-Thiessen, E, Streeten, E A, Styrkarsdottir, U, Swart, K M A, Tan, S-T, Tarnopolsky, M A, Thompson, P, Thomson, C A, Thorsteinsdottir, U, Tikkanen, E, Tranah, G J, Tuomilehto, J, Van Schoor, N M, Verma, A, Vollenweider, P, Völzke, H, Wactawski-Wende, J, Walker, M J, Weedon, M N, Welch, R, Wichman, H E, Widen, E, Williams, F M K, Wilson, J F, Wright, N C, Xie, W, Yu, L, Zhou, Y, Chambers, J C, Döring, A, van Duijn, C M, Econs, M J, Gudnason, V, Kooner, J S, Psaty, B M, Spector, T D, Stefansson, K, Rivadeneira, F, Uitterlinden, A G, Wareham, N J, Ossowski, V, Waterworth, D, Loos, R J F, Karasik, D, Harris, T B, Ohlsson, C & Kiel, D P 2017, ' Large meta-analysis of genome-wide association studies identifies five loci for lean body mass ', Nature Communications, vol. 8, no. 1, 80 . https://doi.org/10.1038/s41467-017-00031-7
Nature Communications, Vol 8, Iss 1, Pp 1-13 (2017)
Nature Communications 8 (2017) 1
Nature Communications, 8:80. Nature Publishing Group
Zillikens, M C, Demissie, S, Hsu, Y-H, Yerges-Armstrong, L M, Chou, W-C, Stolk, L, Livshits, G, Broer, L, Johnson, T, Koller, D L, Kutalik, Z, Luan, J, Malkin, I, Ried, J S, Smith, A V, Thorleifsson, G, Vandenput, L, Hua Zhao, J, Zhang, W, Aghdassi, A, Åkesson, K, Amin, N, Baier, L J, Barroso, I, Bennett, D A, Bertram, L, Biffar, R, Bochud, M, Boehnke, M, Borecki, I B, Buchman, A S, Byberg, L, Campbell, H, Campos Obanda, N, Cauley, J A, Cawthon, P M, Cederberg, H, Chen, Z, Cho, N H, Jin Choi, H, Claussnitzer, M, Collins, F, Cummings, S R, De Jager, P L, Demuth, I, Dhonukshe-Rutten, R A M, Diatchenko, L, Eiriksdottir, G, Enneman, A W, Erdos, M, Eriksson, J G, Eriksson, J, Estrada, K, Evans, D S, Feitosa, M F, Fu, M, Garcia, M, Gieger, C, Girke, T, Glazer, N L, Grallert, H, Grewal, J, Han, B-G, Hanson, R L, Hayward, C, Hofman, A, Hoffman, E P, Homuth, G, Hsueh, W-C, Hubal, M J, Hubbard, A, Huffman, K M, Husted, L B, Illig, T, Ingelsson, E, Ittermann, T, Jansson, J-O, Jordan, J M, Jula, A, Karlsson, M, Khaw, K-T, Kilpeläinen, T O, Klopp, N, Kloth, J S L, Koistinen, H A, Kraus, W E, Kritchevsky, S, Kuulasmaa, T, Kuusisto, J, Laakso, M, Lahti, J, Lang, T, Langdahl, B L, Launer, L J, Lee, J-Y, Lerch, M M, Lewis, J R, Lind, L, Lindgren, C, Liu, Y, Liu, T, Liu, Y, Ljunggren, Ö, Lorentzon, M, Luben, R N, Maixner, W, McGuigan, F E, Medina-Gomez, C, Meitinger, T, Melhus, H, Mellström, D, Melov, S, Michaëlsson, K, Mitchell, B D, Morris, A P, Mosekilde, L, Newman, A, Nielson, C M, O'Connell, J R, Oostra, B A, Orwoll, E S, Palotie, A, Parker, S, Peacock, M, Perola, M, Peters, A, Polasek, O, Prince, R L, Räikkönen, K, Ralston, S H, Ripatti, S, Robbins, J A, Rotter, J I, Rudan, I, Salomaa, V, Satterfield, S, Schadt, E E, Schipf, S, Scott, L, Sehmi, J, Shen, J, Soo Shin, C, Sigurdsson, G, Smith, S, Soranzo, N, Stančáková, A, Steinhagen-Thiessen, E, Streeten, E A, Styrkarsdottir, U, Swart, K M A, Tan, S-T, Tarnopolsky, M A, Thompson, P, Thomson, C A, Thorsteinsdottir, U, Tikkanen, E, Tranah, G J, Tuomilehto, J, van Schoor, N M, Verma, A, Vollenweider, P, Völzke, H, Wactawski-Wende, J, Walker, M, Weedon, M N, Welch, R, Wichmann, H-E, Widen, E, Williams, F M K, Wilson, J F, Wright, N C, Xie, W, Yu, L, Zhou, Y, Chambers, J C, Döring, A, van Duijn, C M, Econs, M J, Gudnason, V, Kooner, J S, Psaty, B M, Spector, T D, Stefansson, K, Rivadeneira, F, Uitterlinden, A G, Wareham, N J, Ossowski, V, Waterworth, D, Loos, R J F, Karasik, D, Harris, T B, Ohlsson, C & Kiel, D P 2017, ' Large meta-analysis of genome-wide association studies identifies five loci for lean body mass ', Nature Communications, vol. 8, 80 . https://doi.org/10.1038/s41467-017-00031-7
Zillikens, M C, Demissie, S, Hsu, Y, Yerges-armstrong, L M, Chou, W, Stolk, L, Livshits, G, Broer, L, Johnson, T, Koller, D L, Kutalik, Z, Luan, J, Malkin, I, Ried, J S, Smith, A V, Thorleifsson, G, Vandenput, L, Hua Zhao, J, Zhang, W, Aghdassi, A, Åkesson, K, Amin, N, Baier, L J, Barroso, I, Bennett, D A, Bertram, L, Biffar, R, Bochud, M, Boehnke, M, Borecki, I B, Buchman, A S, Byberg, L, Campbell, H, Campos Obanda, N, Cauley, J A, Cawthon, P M, Cederberg, H, Chen, Z, Cho, N H, Jin Choi, H, Claussnitzer, M, Collins, F, Cummings, S R, De Jager, P L, Demuth, I, Dhonukshe-rutten, R A M, Diatchenko, L, Eiriksdottir, G, Enneman, A W, Erdos, M, Eriksson, J G, Eriksson, J, Estrada, K, Evans, D S, Feitosa, M F, Fu, M, Garcia, M, Gieger, C, Girke, T, Glazer, N L, Grallert, H, Grewal, J, Han, B, Hanson, R L, Hayward, C, Hofman, A, Hoffman, E P, Homuth, G, Hsueh, W, Hubal, M J, Hubbard, A, Huffman, K M, Husted, L B, Illig, T, Ingelsson, E, Ittermann, T, Jansson, J, Jordan, J M, Jula, A, Karlsson, M, Khaw, K, Kilpeläinen, T O, Klopp, N, Kloth, J S L, Koistinen, H A, Kraus, W E, Kritchevsky, S, Kuulasmaa, T, Kuusisto, J, Laakso, M, Lahti, J, Lang, T, Langdahl, B L, Launer, L J, Lee, J, Lerch, M M, Lewis, J R, Lind, L, Lindgren, C, Liu, Y, Liu, T, Liu, Y, Ljunggren, Ö, Lorentzon, M, Luben, R N, Maixner, W, Mcguigan, F E, Medina-gomez, C, Meitinger, T, Melhus, H, Mellström, D, Melov, S, Michaëlsson, K, Mitchell, B D, Morris, A P, Mosekilde, L, Newman, A, Nielson, C M, O’connell, J R, Oostra, B A, Orwoll, E S, Palotie, A, Parker, S, Peacock, M, Perola, M, Peters, A, Polasek, O, Prince, R L, Räikkönen, K, Ralston, S H, Ripatti, S, Robbins, J A, Rotter, J I, Rudan, I, Salomaa, V, Satterfield, S, Schadt, E E, Schipf, S, Scott, L, Sehmi, J, Shen, J, Soo Shin, C, Sigurdsson, G, Smith, S, Soranzo, N, Stančáková, A, Steinhagen-thiessen, E, Streeten, E A, Styrkarsdottir, U, Swart, K M A, Tan, S, Tarnopolsky, M A, Thompson, P, Thomson, C A, Thorsteinsdottir, U, Tikkanen, E, Tranah, G J, Tuomilehto, J, Van Schoor, N M, Verma, A, Vollenweider, P, Völzke, H, Wactawski-wende, J, Walker, M, Weedon, M N, Welch, R, Wichman, H, Widen, E, Williams, F M K, Wilson, J F, Wright, N C, Xie, W, Yu, L, Zhou, Y, Chambers, J C, Döring, A, Van Duijn, C M, Econs, M J, Gudnason, V, Kooner, J S, Psaty, B M, Spector, T D, Stefansson, K, Rivadeneira, F, Uitterlinden, A G, Wareham, N J, Ossowski, V, Waterworth, D, Loos, R J F, Karasik, D, Harris, T B, Ohlsson, C & Kiel, D P 2017, ' Large meta-analysis of genome-wide association studies identifies five loci for lean body mass ', Nature Communications, vol. 8, no. 1 . https://doi.org/10.1038/s41467-017-00031-7
Nature Communications, 8(1):80. Nature Publishing Group
Zillikens, M C, Demissie, S, Hsu, Y-H, Yerges-Armstrong, L M, Chou, W-C, Stolk, L, Livshits, G, Broer, L, Johnson, T, Koller, D L, Kutalik, Z, Luan, J, Malkin, I, Ried, J S, Smith, A V, Thorleifsson, G, Vandenput, L, Hua Zhao, J, Zhang, W, Aghdassi, A, Åkesson, K, Amin, N, Baier, L J, Barroso, I, Bennett, D A, Bertram, L, Biffar, R, Bochud, M, Boehnke, M, Borecki, I B, Buchman, A S, Byberg, L, Campbell, H, Campos Obanda, N, Cauley, J A, Cawthon, P M, Cederberg, H, Chen, Z, Cho, N H, Jin Choi, H, Claussnitzer, M, Collins, F, Cummings, S R, De Jager, P L, Demuth, I, Dhonukshe-Rutten, R A M, Diatchenko, L, Eiriksdottir, G, Enneman, A W, Erdos, M, Eriksson, J G, Eriksson, J, Estrada, K, Evans, D S, Feitosa, M F, Fu, M, Garcia, M, Gieger, C, Girke, T, Glazer, N L, Grallert, H, Grewal, J, Han, B-G, Hanson, R L, Hayward, C, Hofman, A, Hoffman, E P, Homuth, G, Hsueh, W-C, Hubal, M J, Hubbard, A, Huffman, K M, Husted, L B, Illig, T, Ingelsson, E, Ittermann, T, Jansson, J-O, Jordan, J M, Jula, A, Karlsson, M, Khaw, K-T, Kilpeläinen, T O, Klopp, N, Kloth, J S L, Koistinen, H A, Kraus, W E, Kritchevsky, S, Kuulasmaa, T, Kuusisto, J, Laakso, M, Lahti, J, Lang, T, Langdahl, B L, Launer, L J, Lee, J-Y, Lerch, M M, Lewis, J R, Lind, L, Lindgren, C, Liu, Y, Liu, T, Liu, Y, Ljunggren, Ö, Lorentzon, M, Luben, R N, Maixner, W, McGuigan, F E, Medina-Gomez, C, Meitinger, T, Melhus, H, Mellström, D, Melov, S, Michaëlsson, K, Mitchell, B D, Morris, A P, Mosekilde, L, Newman, A, Nielson, C M, O'Connell, J R, Oostra, B A, Orwoll, E S, Palotie, A, Parker, S C J, Peacock, M, Perola, M, Peters, A, Polasek, O, Prince, R L, Räikkönen, K, Ralston, S H, Ripatti, S, Robbins, J A, Rotter, J I, Rudan, I, Salomaa, V, Satterfield, S, Schadt, E E, Schipf, S, Scott, L, Sehmi, J, Shen, J, Soo Shin, C, Sigurdsson, G, Smith, S, Soranzo, N, Stančáková, A, Steinhagen-Thiessen, E, Streeten, E A, Styrkarsdottir, U, Swart, K M A, Tan, S-T, Tarnopolsky, M A, Thompson, P, Thomson, C A, Thorsteinsdottir, U, Tikkanen, E, Tranah, G J, Tuomilehto, J, van Schoor, N M, Verma, A, Vollenweider, P, Völzke, H, Wactawski-Wende, J, Walker, M, Weedon, M N, Welch, R, Wichmann, H-E, Widen, E, Williams, F M K, Wilson, J F, Wright, N C, Xie, W, Yu, L, Zhou, Y, Chambers, J C, Döring, A, van Duijn, C M, Econs, M J, Gudnason, V, Kooner, J S, Psaty, B M, Spector, T D, Stefansson, K, Rivadeneira, F, Uitterlinden, A G, Wareham, N J, Ossowski, V, Waterworth, D, Loos, R J F, Karasik, D, Harris, T B, Ohlsson, C & Kiel, D P 2017, ' Large meta-analysis of genome-wide association studies identifies five loci for lean body mass ', Nature Communications, vol. 8, no. 1, pp. 80 . https://doi.org/10.1038/s41467-017-00031-7
Nature communications, vol. 8, no. 1, pp. 80
Lean body mass, consisting mostly of skeletal muscle, is important for healthy aging. We performed a genome-wide association study for whole body (20 cohorts of European ancestry with n = 38,292) and appendicular (arms and legs) lean body mass (n = 2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8ce3259a42db953a3e53cb966397d4f4
https://hdl.handle.net/11858/00-001M-0000-002D-C532-811858/00-001M-0000-002D-C534-4
https://hdl.handle.net/11858/00-001M-0000-002D-C532-811858/00-001M-0000-002D-C534-4
Autor:
Tyler W. H. Backman, Thomas Girke
Publikováno v:
BMC bioinformatics, vol 17, iss 1
BMC Bioinformatics
BMC Bioinformatics
Background Next-generation sequencing (NGS) has revolutionized how research is carried out in many areas of biology and medicine. However, the analysis of NGS data remains a major obstacle to the efficient utilization of the technology, as it require
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::25b4d081647d50e8c01f71e7bf4ae5b3
https://escholarship.org/uc/item/64q9c06m
https://escholarship.org/uc/item/64q9c06m
Publikováno v:
Nucleic Acids Research
ChemMine Tools is an online service for small molecule data analysis. It provides a web interface to a set of cheminformatics and data mining tools that are useful for various analysis routines performed in chemical genomics and drug discovery. The s
Publikováno v:
Bioinformatics
Bioinformatics (Oxford, England), vol 24, iss 13
ISMB
Bioinformatics (Oxford, England), vol 24, iss 13
ISMB
Motivation: The prediction of biologically active compounds is of great importance for high-throughput screening (HTS) approaches in drug discovery and chemical genomics. Many computational methods in this area focus on measuring the structural simil
Publikováno v:
Plant Physiology. 138:573-577
Chemical genomics is a promising new technology for studying gene functions in the context of living organisms or cell systems. It complements existing molecular and genetics tools (e.g. mutagenesis, RNAi) by allowing fine-tunable in vivo modulations
Publikováno v:
Bioinformatics (Oxford, England), vol 30, iss 12
Bioinformatics
Bao, E; Jiang, T; & Girke, T. (2014). AlignGraph: Algorithm for secondary de novo genome assembly guided by closely related references. Bioinformatics, 30(12), I319-I328. doi: 10.1093/bioinformatics/btu291. UC Riverside: Retrieved from: http://www.escholarship.org/uc/item/875037pj
Bioinformatics
Bao, E; Jiang, T; & Girke, T. (2014). AlignGraph: Algorithm for secondary de novo genome assembly guided by closely related references. Bioinformatics, 30(12), I319-I328. doi: 10.1093/bioinformatics/btu291. UC Riverside: Retrieved from: http://www.escholarship.org/uc/item/875037pj
Motivation: De novo assemblies of genomes remain one of the most challenging applications in next-generation sequencing. Usually, their results are incomplete and fragmented into hundreds of contigs. Repeats in genomes and sequencing errors are the m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e0d563852d947537b940d632473d9408
https://escholarship.org/uc/item/875037pj
https://escholarship.org/uc/item/875037pj
Publikováno v:
Bioinformatics
Bioinformatics (Oxford, England), vol 27, iss 18
Bioinformatics (Oxford, England), vol 27, iss 18
Motivation: Similarity clustering of next-generation sequences (NGS) is an important computational problem to study the population sizes of DNA/RNA molecules and to reduce the redundancies in NGS data. Currently, most sequence clustering algorithms a
Publikováno v:
BMC Bioinformatics, Vol 11, Iss 1, p 205 (2010)
BMC bioinformatics, vol 11, iss 1
Horan, K; Shelton, CR; & Girke, T. (2010). Predicting conserved protein motifs with Sub-HMMs. BMC Bioinformatics, 11. doi: 10.1186/1471-2105-11-205. UC Riverside: Retrieved from: http://www.escholarship.org/uc/item/5t67m6g1
BMC Bioinformatics
BMC bioinformatics, vol 11, iss 1
Horan, K; Shelton, CR; & Girke, T. (2010). Predicting conserved protein motifs with Sub-HMMs. BMC Bioinformatics, 11. doi: 10.1186/1471-2105-11-205. UC Riverside: Retrieved from: http://www.escholarship.org/uc/item/5t67m6g1
BMC Bioinformatics
BackgroundProfile HMMs (hidden Markov models) provide effective methods for modeling the conserved regions of protein families. A limitation of the resulting domain models is the difficulty to pinpoint their much shorter functional sub-features, such
Publikováno v:
Bioinformatics (Oxford, England), vol 26, iss 7
Bioinformatics
Bioinformatics
Motivation: Similarity searching and clustering of chemical compounds by structural similarities are important computational approaches for identifying drug-like small molecules. Most algorithms available for these tasks are limited by their speed an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2fba7a2263aa723fdd294cbfb7a21954
https://escholarship.org/uc/item/3bb0p0n9
https://escholarship.org/uc/item/3bb0p0n9