Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Yuxiang Huang"'
Autor:
Jinping Si, Qian Ji, Yong Diao, Hexin Tan, Lei Zhang, Yuxiang Huang, Jingjing Liu, Dong-Hong Chen, Zhiying Guo, Zongyou Lv
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-12 (2018)
Scientific Reports
Scientific Reports
Under hypoxic conditions, the expression of Vitreoscilla hemoglobin (VHb) in plants is proposed to increase the productivity of certain oxygen-requiring metabolic pathways by promoting the delivery of oxygen. Tropane alkaloids (TAs) are a class of im
Publikováno v:
Antioxidants. 11:304
Eukaryotic cells frequently experience fluctuations of the external and internal environments, such as changes in nutrient, energy and oxygen sources, and protein folding status, which, after reaching a particular threshold, become a type of stress.
Publikováno v:
J R Soc Interface
Understanding the bonding mechanism of the interfacial region between bamboo and adhesives is essential for accelerating the development of improved adhesives for advanced bamboo-based materials. In this study, Br-labelled phenol-formaldehyde (PF) re
Publikováno v:
Journal of Plant Biology. 59:203-214
Indole alkaloids are widely distributed secondary metabolites that exhibit a broad range of pharmacological activities. They are synthesized through plant biosynthetic pathways involving complex enzyme activities and regulatory strategies. Since many
Publikováno v:
Acta Biochimica et Biophysica Sinica. 48:229-237
Nasopharyngeal carcinoma (NPC) is one of the most common malignant tumors with poor prognosis and recurrence in South China. The hard eradication of NPC in clinic is predominantly due to cancer stem cells (CSCs). Increasing evidence revealed that the
Autor:
B. Paul Morgan, Ruben Abagyan, Hongbin Song, Yuxiang Huang, Colin A. Smith, Stephen Tomlinson
Publikováno v:
Journal of Biological Chemistry. 280:34073-34079
CD59 is a 77-amino acid membrane glycoprotein that plays an important role in regulating the terminal pathway of complement by inhibiting formation of the cytolytic membrane attack complex (MAC or C5b-9). The MAC is formed by the self assembly of C5b
Autor:
Carl Atkinson, Stephen Tomlinson, Nico van Rooijen, B. Paul Morgan, Yuxiang Huang, Fei Qiao, Michelle Elvington
Publikováno v:
Blood, 119(25), 6043-6051. American Society of Hematology
Elvington, M, Huang, Y X, Morgan, B P, Qiao, F, van Rooijen, N, Atkinson, C & Tomlinson, S 2012, ' A targeted complement-dependent strategy to improve the outcome of mAb therapy, and characterization in a murine model of metastatic cancer ', Blood, vol. 119, no. 25, pp. 6043-6051 . https://doi.org/10.1182/blood-2011-10-383232
Elvington, M, Huang, Y X, Morgan, B P, Qiao, F, van Rooijen, N, Atkinson, C & Tomlinson, S 2012, ' A targeted complement-dependent strategy to improve the outcome of mAb therapy, and characterization in a murine model of metastatic cancer ', Blood, vol. 119, no. 25, pp. 6043-6051 . https://doi.org/10.1182/blood-2011-10-383232
Complement inhibitors expressed on tumor cells provide an evasion mechanism against mAb therapy and may modulate the development of an acquired antitumor immune response. Here we investigate a strategy to amplify mAb-targeted complement activation on
Autor:
Yuxiang Huang, Veronica Min Sien Lam, Shannon Wing-Ngor Au, Deborah Man Yee Au, Paul C. Engel, Mei Yee Choi
Publikováno v:
Molecular genetics and metabolism. 93(1)
In an attempt to investigate the molecular mechanism underlying human glucose-6-phosphate dehydrogenase (G6PD) deficiency caused by two mutations, G6PD(Plymouth) (G163D) and G6PD(Mahidol) (G163S), the two variants were constructed by site-directed mu
Publikováno v:
The Journal of biological chemistry. 281(37)
CD59 is a membrane glycoprotein that regulates formation of the cytolytic membrane attack complex (MAC or C5b-9) on host cell membranes. It functions by binding to C8 (alpha chain) and C9 after their structural rearrangement during MAC assembly. Prev