Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Yan-Na Cheng"'
Publikováno v:
International Journal of Biological Macromolecules. 107:349-362
Previous studies demonstrated that SIP-SII, a sulfated derivative of SIP that is isolated from the ink of Sepiella maindroni, showed significant inhibition of tumor growth and metastasis. In this study, the effects of SIP-SII on the migration, invasi
Autor:
Hui-Hui Zhang, Ying Zhang, Hong-Yuan Wang, Zhen-Ning Lu, Lu-Gang Yu, Yan-Na Cheng, Fu-Lian Gong, Xiu-Li Guo, Zhao-Peng Liu
Publikováno v:
INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY
Multidrug resistance (MDR) is one of major obstacles to effective chemotherapeutic treatment of cancer. This study showed that DHPAC, 2-(6-ethoxy-3-(3-ethoxyphenylamino) -1-methyl-1,4-dihydroindeno[1,2-c]pyrazol-7-yloxy) acetamide, a novel compound t
Autor:
Yan Zhang, Fengshan Wang, Wenjie Jiang, Xinlei Song, Chunhui Liu, Yan-Na Cheng, Hongzhi Cao, Aizhen Zong, Yuhong Liu, Yikang Shi, Fangling Du
Publikováno v:
Carbohydrate Polymers. 129:50-54
Our previous studies demonstrated that SIP-S had anti-metastatic activity and inhibited the growth of metastatic foci. Here we report the anti-tumor and immunoregulatory potential of SIP-S. SIP-S could significantly inhibit tumor growth in S180-beari
Tat PTD–endostatin: A novel anti-angiogenesis protein with ocular barrier permeability via eye-drops
Publikováno v:
Biochimica et Biophysica Acta (BBA) - General Subjects. 1850:1140-1149
Background Endostatin, a specific inhibitor of endothelial cell proliferation and angiogenesis, has been proved to have effects on ocular neovascular diseases by intraocular injection. In order to increase its permeability to ocular barriers and make
Autor:
Peng George Wang, Haiqiang Jiang, Yuguo Liu, Yuhong Liu, Lingchuan Xu, Fengshan Wang, Yan-Na Cheng
Publikováno v:
Carbohydrate Polymers. 106:42-48
Two sulfated derivatives (PRP-S1 and PRP-S2) of a β-glucan from Phellinus ribis with different degrees of substitution were obtained by chlorosulfonic acid method. The derivatives could block formation of new vessels in zebrafish and inhibit the pro
Autor:
Pingli Li, Fengshan Wang, Yuliang Xiao, Lei Zheng, Yan-Na Cheng, Zhen Han, Xinke Zhang, Juan Li, Qian Zhang
Publikováno v:
Cancer Letters. 337:237-247
In the present study, the immunomodulatory and synergistic anti-tumor activity of thymosin α1-thymopentin fusion peptide (Tα1-TP5) was investigated in vivo. In addition, the potential receptor of Tα1-TP5 was investigated by surface plasmon resonan
Publikováno v:
Biochimica et biophysica acta. 1860(11 Pt)
Methods 8-week-age male ApoE−/− mice were fed with the atherogenic diet together with or without tested compounds (rosuvastatin calcium, α-LNA-LMWCS, LMWCS and α-LNA) for 16 weeks. When the animals were killed, blood plasma was isolated to test
Autor:
Shu-Xiang Cui, Wei Tang, Xian-Jun Qu, Yan-Na Cheng, Jianjun Gao, Wenfang Xu, Zu-Hua Gao, Xia Xue
Publikováno v:
Microvascular Research. 82:122-130
Our previous study revealed that LYP, a bestatin dimethylaminoethyl ester, inhibited the growth of human ovarian carcinoma ES-2 xenografts in mice and suppressed aminopeptidase N (APN/CD13) activity more potently than bestatin. In this study, we exam
Autor:
Yi Yuan, Xiao-Fan Zhang, Shu-Xiang Cui, Zu-Hua Gao, Wenfang Xu, Cui-Rong Zhao, Yan-Na Cheng, Xian-Jun Qu, Jianjun Gao, Wei Tang
Publikováno v:
Investigational New Drugs. 29:574-582
LYP is a bestatin dimethylaminoethyl ester which inhibits aminopeptidase N (APN/CD13). Our goal in this study was to evaluate LYP as a candidate compound for cancer treatment, beginning by studying its inhibitory effects on tumors and then comparing
Autor:
Decai Wang, Qian Zhang, Chuanqing Zhong, Pingli Li, Juan Li, Yan-Na Cheng, Xinke Zhang, Yuliang Xiao, Rui Cao, Juzheng Sheng, Fengshan Wang
Publikováno v:
International journal of pharmaceutics. 465(1-2)
The purpose of this report was to demonstrate the effect of amphiphilic polysaccharides-based self-assembling micelles on enhancing the oral absorption of low molecular weight chondroitin sulfate (LMCS) in vitro and in vivo, and identify the transepi