Zobrazeno 1 - 10
of 51
pro vyhledávání: '"Wenbing Yao"'
Publikováno v:
International Journal of Biological Macromolecules. 149:1180-1188
Ulcerative colitis (UC) is a chronic inflammatory bowel disease of unknown etiology with increasing incidence world widely. Previous studies have indicated that the α-D-glucan YCP purified from the mycelium of the marine fungus Phoma herbarum YS4108
Autor:
Wenbing Yao, Xiaoda Song, Yuting Yi, Hong Tian, Xiangdong Gao, Siwei Deng, Mengjiao He, Li Liu
Publikováno v:
Process Biochemistry. 89:29-36
Monellin, one kind of most sweet proteins, could be used instead of carbohydrates in the diabetic diet and pharmaceuticals. However, the critical problem interferes with monellin usage in the food or pharmaceutical industry was its unstable at high t
Autor:
Xiaoda Song, Fengyuan Xu, Qi He, Xiangdong Gao, Wenbing Yao, Li Liu, Sheng Li, Chun Pan, Bohao Wang
Publikováno v:
Biomolecules
Volume 11
Issue 9
Biomolecules, Vol 11, Iss 1358, p 1358 (2021)
Volume 11
Issue 9
Biomolecules, Vol 11, Iss 1358, p 1358 (2021)
The activity and function of proteins can be improved by incorporation of non-canonical amino acids (ncAAs). To avoid the tedious synthesis of a large number of chiral phenylalanine derivatives, we synthesized the corresponding phenylpyruvic acid pre
Autor:
Wanli Zhang, Tengfang Long, Hong Tian, Wenbing Yao, Jie Zheng, Lei Liu, Julian D. Hegemann, Youqi Tao, Jiale Quan, Huan Wang, Motonari Uesugi
Publikováno v:
Angewandte Chemie (International ed. in English). 60(24)
Tyrosine nitration of proteins is one of the most important oxidative post-translational modifications in vivo. A major obstacle for its biochemical and physiological studies is the lack of efficient and chemoselective protein tyrosine nitration reag
Publikováno v:
Analytical Biochemistry. 573:1-7
Given that the biological functions of proteins may decrease or even be lost due to degradation by proteases, it is of great significance to identify potential proteases that degrade protein drugs during systemic circulation. In this work, we describ
Publikováno v:
Preparative Biochemistry & Biotechnology. 48:144-150
Human epidermal growth factor receptor 2 (HER2) is a powerful target for cancer immune therapy. The development of anti-HER2 monoclonal antibodies targeting different domains of HER2 is quite effective. However, the selection and production of multiv
Publikováno v:
Carbohydrate Polymers. 176:140-151
An acidic polysaccharide (SERP1) was isolated from the residue of Sarcandra glabra (Thunb.) Nakai by water extraction and purified by decoloration and ion exchange chromatography. The structure of SERP1 was determined by HPLC, HPSEC-MALLS, FT-IR, and
Publikováno v:
Bioprocess and Biosystems Engineering. 40:675-681
Heparosan, the capsular polysaccharide discovered in many pathogenic bacteria, is a promising material for heparin preparation. In this study, the Pasteurella multocida heparosan synthase 1 (PmHS1) module was used to synthesize heparosan with control
Publikováno v:
Journal of the American Chemical Society. 140(49)
The efficient delivery of proteins into cells is needed to fully realize the potential of protein-based therapeutics. Current protein delivery strategies generally suffer from poor endosomal escape and low tolerance for serum. Here, the genetic fusio
Autor:
Teng Ma, Yongkang Wang, Ying Li, Peng Qian, Weisheng Lu, Xiangdong Gao, Wenbing Yao, Hong Tian
Publikováno v:
Biochemical Pharmacology. 182:114209
Diabetic cardiomyopathy is one of the major cardiovascular complications of diabetes mellitus associated with left ventricular diastolic dysfunction. There are still no specific therapeutic guidelines for the disease. In recent years, glucagon-like p