Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Weihui Zhang"'
Publikováno v:
Journal of Cellular Biochemistry. 120:8160-8168
Background Annexin A2 (ANXA2) plays a crucial role in acute pancreatitis (AP). However, its potential mechanism remains unclear. Methods In the present study, we used caerulein-treated AR42J rat pancreatic acinar cells as cell model of AP to investig
Publikováno v:
Molecular Medicine Reports
Acute pancreatitis (AP) is a common digestive disorder with high morbidity and mortality. The present study aimed to investigate the expression of early growth response protein 1 (Egr1), and the effect of competing endogenous (ce)RNA network on tryps
Publikováno v:
Molecular Medicine Reports
The present study used caerulein stimulation of AR42J rat pancreatic cells as an in vitro acute pancreatitis (AP) model to investigate proteins differentially expressed in apoptosis and necrosis. AR42J cells were stimulated with 10‑8mol/l caerulein
Publikováno v:
Molecular Medicine Reports
Hematological abnormalities are frequently observed in patients with liver cirrhosis (LC). A previous study demonstrated that the apoptosis and damage of endothelial cells could cause the hematological abnormalities in LC. Protein kinases are one of
Autor:
Weihui Zhang, Zhituo Li, Haijun Sun, Jiangtao Chu, Biao Ma, Dali Zhao, Dongbo Xue, Xueming Zhang
Publikováno v:
Acta biochimica et biophysica Sinica. 52(2)
The aim of this study was to investigate the role and mechanism of miR-155 in regulating autophagy in a caerulein-induced acute pancreatitis (AP) cellular model. GFP-LC3 immunofluorescence assay was performed to detect autophagy vesicle formation in
Autor:
Zhituo Li, Dali Zhao, Weihui Zhang, Yang Huang, Dongbo Xue, Bo Gao, Biao Ma, Yong Zhang, Xueming Zhang
Publikováno v:
Molecular Medicine Reports
Acute pancreatitis (AP) exhibits high morbidity and mortality rates. The onset of AP is characterized by early trypsinogen activation. The present study aimed to investigate the expression of microRNA (miR)-92a-3p and early growth response protein 1
Publikováno v:
Molecular Medicine Reports. 14:590-598
Acute pancreatitis (AP) is a common acute digestive tract disease, with increased morbidity and mortality, and an unclear pathogenesis. Trypsinogen activation in pancreatic acinar cells may be the primary mechanism underlying the development of AP. P
Publikováno v:
Molecular Medicine Reports
In recent years, an increasing number of studies on the roles of macrophages in tumors, immune responses and metabolism have been published, in which macrophage polarization has been an extensively discussed topic. In the present study, differentiall
Autor:
Weihui Zhang, Zu-Hua Gao, Yuguo Zhang, Bo Gao, Zhengpeng Yang, Xueming Zhang, Dongbo Xue, Yongming Huang
Publikováno v:
PLoS ONE
PLoS ONE, Vol 12, Iss 3, p e0174142 (2017)
PLoS ONE, Vol 12, Iss 3, p e0174142 (2017)
Liver cirrhosis is recognized as being the consequence of immune-mediated hepatocyte damage and repair processes. However, the regulation of these immune responses underlying liver cirrhosis has not been elucidated. In this study, we used GEO dataset
Publikováno v:
Molecular medicine reports. 16(5)
The present study aimed to screen for differentially expressed extracellular microRNAs (miRNAs) during the development of acute pancreatitis (AP) and validate the miRNA expression in the plasma of patients with AP. The culture medium of taurolithocho