Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Ryo, Ito"'
Autor:
Kensuke Sakuma, Noriko Tsubooka-Yamazoe, Kiyohiro Hashimoto, Nozomu Sakai, Shinya Asano, Saori Watanabe-Matsumoto, Takeshi Watanabe, Bunnai Saito, Hirokazu Matsumoto, Hikaru Ueno, Ryo Ito, Taro Toyoda
Publikováno v:
Stem Cell Research & Therapy, Vol 14, Iss 1, Pp 1-15 (2023)
Abstract Background Transplantation of differentiated cells from human-induced pluripotent stem cells (hiPSCs) holds great promise for clinical treatments. Eliminating the risk factor of malignant cell transformation is essential for ensuring the saf
Externí odkaz:
https://doaj.org/article/a21dd5df379540a8874afc1118b6fef0
Autor:
Yuta Tsujisaka, Takeshi Hatani, Chikako Okubo, Ryo Ito, Azuma Kimura, Megumi Narita, Kazuhisa Chonabayashi, Shunsuke Funakoshi, Antonio Lucena-Cacace, Taro Toyoda, Kenji Osafune, Takeshi Kimura, Hirohide Saito, Yoshinori Yoshida
Publikováno v:
Stem Cell Reports. 17:1772-1785
For regenerative cell therapies using pluripotent stem cell (PSC)-derived cells, large quantities of purified cells are required. Magnetic-activated cell sorting (MACS) is a powerful approach to collect target antigen-positive cells; however, it rema
Autor:
Ryo Ito, Hiroki Shimada, Kengo Yazawa, Ikuko Sato, Yuuki Imai, Akira Sugawara, Atsushi Yokoyama
Publikováno v:
Biochemistry and Biophysics Reports, Vol 5, Iss C, Pp 134-140 (2016)
DNA methylation is closely involved in the regulation of cellular differentiation, including chondrogenic differentiation of mesenchymal stem cells. Recent studies showed that Ten–eleven translocation (TET) family proteins converted 5-methylcytosin
Externí odkaz:
https://doaj.org/article/75e6db5d91b8401e9dde9afe7feb3b3e
Autor:
Mai Mochizuki, Sadafumi Kawamura, Kazuto Matsuura, Keiichi Tamai, Takayuki Imai, Wataru Iwai, Jun Yasuda, Akira Sugawara, Yukinori Asada, Makoto Abue, Tomoko Yamazaki, Haruna Fujimori, Rie Shibuya-Takahashi, Satoshi Saijoh, Ryo Ito, Yukio Katori, Mao Nakamura-Shima, Kazuo Sugamura, Kazunori Yamaguchi, Yu Katayose, Yuta Wakui, Kennichi Satoh
Publikováno v:
Biochemical and Biophysical Research Communications. 537:132-139
Cancer stem cells (CSCs) are believed to cause cancer metastasis and recurrence. BEX2 (brain expressed X-linked gene 2) is a CSC-related gene that is expressed in dormant CSCs in cholangiocarcinoma and induces resistance against chemotherapy. The aim
Publikováno v:
Biochemical and Biophysical Research Communications. 534:672-679
Aldosterone is synthesized in the adrenal by the aldosterone synthase CYP11B2. Although the control of CYP11B2 expression is important to maintain the mineral homeostasis, its overexpression induced by the depolarization-induced calcium (Ca2+) signal
Publikováno v:
Biochemical and Biophysical Research Communications. 489:21-28
CYP11B2 is a key enzyme involved in the synthesis of the mineralocorticoid aldosterone. CYP11B2 expression in the adrenal glands is controlled by the renin-angiotensin system (RAS), and plays an important role in the maintenance of electrolyte metabo
Autor:
Nobuhiro Nishigaki, Hikaru Ueno, Yasufumi Miyamoto, Hirohisa Miyashita, Koji Takeuchi, Yoshiyuki Tsujihata, Minoru Maruyama, Ryo Ito, Hitomi Ogino, Yusuke Moritoh, Shin-ichi Abe
Publikováno v:
PLoS ONE, Vol 14, Iss 9, p e0222653 (2019)
PLoS ONE
PLoS ONE
GPR40/FFAR1 is a Gq protein-coupled receptor expressed in pancreatic β cells and enteroendocrine cells, and mediates insulin and incretin secretion to regulate feeding behavior. Several GPR40 full agonists have been reported to reduce food intake in
Autor:
Ikuko Sato, Ryo Ito, Kengo Yazawa, Hiroki Shimada, Yuuki Imai, Atsushi Yokoyama, Akira Sugawara
Publikováno v:
Biochemistry and Biophysics Reports
Biochemistry and Biophysics Reports, Vol 5, Iss C, Pp 134-140 (2016)
Biochemistry and Biophysics Reports, Vol 5, Iss C, Pp 134-140 (2016)
DNA methylation is closely involved in the regulation of cellular differentiation, including chondrogenic differentiation of mesenchymal stem cells. Recent studies showed that Ten–eleven translocation (TET) family proteins converted 5-methylcytosin
Autor:
Kiyoshi Takagi, Jun Kanno, Atsushi Yokoyama, Akira Sugawara, Tetsuya Sato, Katsuhide Igarashi, Yasuyuki Ohkawa, Takashi Baba, Ryo Ito, Maky Otsuka, Yurina Shishido, Ken Ichirou Morohashi
Publikováno v:
Journal of Biological Chemistry. 289:18152-18162
Regulation of spatiotemporal gene expression in higher eukaryotic cells is critical for the precise and orderly development of undifferentiated progenitors into committed cell types of the adult. It is well known that dynamic epigenomic regulation (i
Publikováno v:
Journal of Biological Chemistry. 287:19792-19803
TATA-binding protein-like protein (TLP) is involved in development, checkpoint, and apoptosis through potentiation of gene expression. TLP-overexpressing human cells, especially p53-containing cells, exhibited a decreased growth rate and increased pr