Zobrazeno 1 - 10
of 32
pro vyhledávání: '"Paul Frankel"'
Autor:
Tamer Othman, Christopher Ruel, Paul Frankel, Alexander A. Merleev, Guillaume Luxardi, Emanual Maverakis, Mehrdad Abedi, Raghuveer Ranganathan, Jasmine Zain, Lihua E Budde, Matthew Mei, Aaron S Rosenberg, Rasmus T Hoeg, Caitlin Costello, Francine M. Foss, Basem M. William, H. Kent Holland, Miguel Villalona-Calero, Elad Sharon, Joseph M Tuscano
Publikováno v:
Blood. 140:9446-9447
Autor:
David L. Selwood, Paul Frankel, Tamas Yelland, Ian Zachary, Filipa Mota, Snezana Djordjevic, Constantina Fotinou, Andrew O’Leary, John Martin, Anastasia Patsiarika, Jennie A. Hutton, Jennifer Parker, A. W. Edith Chan
Publikováno v:
Chembiochem
Vascular endothelial growth factors (VEGFs) regulate significant pathways in angiogenesis, myocardial and neuronal protection, metabolism, and cancer progression. The VEGF‐B growth factor is involved in cell survival, anti‐apoptotic and antioxida
Autor:
Tamer Othman, Pamela B. Allen, Paul Frankel, Shari Daniels, Lacolle Peters, Joseph Tuscano, Steven T. Rosen, Geoffrey Shouse, Elad Sharon, Alexey V. Danilov, Nora Ruel, Tanya Siddiqi, Leslie Popplewell, Alex F. Herrera, Stella Khoo
Publikováno v:
Blood. 138:1407-1407
Introduction: Diffuse large B-cell lymphomas (DLBCL) transformed from indolent B-cell non-Hodgkin lymphomas (B-NHL) or Richter transformation (RT) from chronic lymphocytic leukemia/small lymphocytic lymphoma (CLL) are associated with a poor prognosis
Autor:
Jasmine Zain, Christopher Ruel, Christina Poh, Brian A. Jonas, Francine M. Foss, Mehrdad Abedi, Paul Frankel, Edward M. Newman, Joseph Tuscano, Aaron S. Rosenberg, Lihua E. Budde, Basem M. William, Emily Schwab, Caitlin Costello
Publikováno v:
Blood. 134:760-760
Introduction Both blinatumomab and lenalidomide have proven, but limited, efficacy in relapsed/refractory (R/R) non-Hodgkin's lymphoma (NHL). Failure of blinatumomab to mediate durable responses is due to its inability to recruit competent cytotoxic
Autor:
Joanne E. Mortimer, Arti Hurria, Masaya Kai, Meng Yin Hsieh, Duc Nguyen, Shiuan Chen, Paul Frankel, Chu Peiguo, Shang Wu, Laura Kruper, John H. Yim, Noriko Kanaya, Courtney Vito, Yuan Yuan, Nymph Chan, Jun Wu, George Somlo, Behnam Badie, Xueli Liu, Michele Kirschenbaum
Publikováno v:
The Journal of steroid biochemistry and molecular biology. 170
The research was to appraise the utility of the patient-derived tumor xenografts (PDXs) as models of estrogen receptor positive (ER+HER2- and ER+HER2+) breast cancers. We compared protein expression profiles by Reverse Phase Protein Array (RPPA) in t
Autor:
Birger Herzog, Manfred Jünemann-Ramírez, Ian Zachary, Caroline Pellet-Many, Ian M. Evans, Paul Frankel
Publikováno v:
Biochemical Journal
BIOCHEM J, 435 609-618. (2011)
BIOCHEM J, 435 609-618. (2011)
NRP1 (neuropilin-1) is a co-receptor for members of the VEGF (vascular endothelial growth factor) family in endothelial cells, but is increasingly implicated in signalling induced by other growth factors. NRP1 is expressed in VSMCs (vascular smooth m
Publikováno v:
Biochemical Society Transactions. 37:1171-1178
NRPs (neuropilins) are receptors for class 3 semaphorins, polypeptides essential for axonal guidance, and for members of the VEGF (vascular endothelial growth factor) family of angiogenic cytokines. While mutant mouse studies show that NRP1 is essent
Autor:
Ian Zachary, Pauliina Lehtolainen, Paul Frankel, Giovanna M. D'Abaco, Lili Cheng, Caroline Pellet-Many, Michelle Tickner
Publikováno v:
EMBO reports. 9:983-989
Neuropilin 1 (NRP1), a non-tyrosine kinase receptor for vascular endothelial growth factor and class 3 Semaphorins, is highly expressed in many human tumour cell lines, but its function is poorly understood. Here, we describe the expression of a new
Publikováno v:
FEBS Journal. 275:2372-2384
The finding of a genome-wide oscillation in transcription that gates cells into S phase and coordinates mitochondrial and metabolic functions has altered our understanding of how the cell cycle is timed and how stable cellular phenotypes are maintain
Publikováno v:
Biochemical Journal. 411:211-226
NRPs (neuropilins) are co-receptors for class 3 semaphorins, polypeptides with key roles in axonal guidance, and for members of the VEGF (vascular endothelial growth factor) family of angiogenic cytokines. They lack a defined signalling role, but are