Zobrazeno 1 - 10
of 60
pro vyhledávání: '"Owen, L"'
Autor:
Daniel J.H. Nightingale, Paul D. W. Kirk, Laurent Gatto, Owen L. Vennard, Kathryn S. Lilley, Aikaterini Geladaki, Oliver M. Crook
Publikováno v:
PLoS Computational Biology, Vol 16, Iss 11, p e1008288 (2020)
PLoS Computational Biology
PLOS Computational Biology, Vol. 16, no. 11, p. e1008288 [1-21] (2020)
bioRxiv, (2020)
PLoS Computational Biology
PLOS Computational Biology, Vol. 16, no. 11, p. e1008288 [1-21] (2020)
bioRxiv, (2020)
The cell is compartmentalised into complex micro-environments allowing an array of specialised biological processes to be carried out in synchrony. Determining a protein’s sub-cellular localisation to one or more of these compartments can therefore
Autor:
Christopher, Josie A., Geladaki, Aikaterini, Dawson, Charlotte S., Vennard, Owen L., Lilley, Kathryn S.
Publikováno v:
Mol Cell Proteomics
The internal environment of cells is molecularly crowded, which requires spatial organization via subcellular compartmentalization. These compartments harbor specific conditions for molecules to perform their biological functions, such as coordinatio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f73d9c81edd2f9ddeba28b8d25a41ecf
https://www.repository.cam.ac.uk/handle/1810/332656
https://www.repository.cam.ac.uk/handle/1810/332656
Autor:
Laura J. Parry, Edwina Jap, Chen Huei Leo, John D. Horowitz, Chengxue Qin, Owen L. Woodman, Barbara K Kemp-Harper, Mandy Li, Anida Velagic, Rebecca H. Ritchie, Jarryd Anthonisz, Nicola Kahlberg
Publikováno v:
Antioxidants & Redox Signaling. 32:60-77
Aim: Impairment of tissue responsiveness to exogenous and endogenous nitric oxide (NO•), known as NO• resistance, occurs in many cardiovascular disease states, prominently in diabetes and especiall...
Publikováno v:
Tobacco Control, 2003 Dec 01. 12(4), 434-434.
Externí odkaz:
https://www.jstor.org/stable/20747667
Autor:
David I. Conway, Nigel Milne, Alex D. McMahon, Jeremy Bagg, Innocent Manda, Michael O. Rivett, Owen L. Phiri, Vicky Milne, Emma Mbalame, Robert M. Kalin, Peaches Phiri, Lorna M. D. Macpherson, Marc J. Addison
Publikováno v:
Water
Volume 13
Issue 8
Water, Vol 13, Iss 1106, p 1106 (2021)
Volume 13
Issue 8
Water, Vol 13, Iss 1106, p 1106 (2021)
Hidden hot springs likely impact rural water supplies in Malawi’s Rift Valley with excess dissolved fluoride leading to localised endemic severe dental fluorosis. Predicting their occurrence is a challenge
Malawi’s groundwater data archive i
Malawi’s groundwater data archive i
Publikováno v:
Current Medicinal Chemistry. 25:4402-4415
In acute myocardial infarction (AMI), the first line of treatment is to rapidly restore blood flow to the ischemic myocardium to limit infarct size. It is now well established that though clearly beneficial, the positive outcomes of this intervention
Publikováno v:
Assay and drug development technologies. 16(1)
Protease-activated receptor 2 (PAR2) is a proinflammatory G-protein coupled receptor (GPCR) that is activated by inflammatory proteases, and its activation initiates signaling pathways that modulate the nonselective cation channel transient receptor
Publikováno v:
American journal of physiology. Gastrointestinal and liver physiology. 313(6)
It is generally accepted that the gastric mucus layer provides a protective barrier between the lumen and the mucosa, shielding the mucosa from acid and digestive enzymes and preventing autodigestion of the stomach epithelium. However, the precise me
Publikováno v:
Pharmacological Research. 81:26-33
The study aimed to determine the effect of 3',4'-dihydroxyflavonol (DiOHF) on mitochondrial function, in particular opening of the mitochondrial permeability transition pore (mPTP), respiratory function and reactive oxygen species (ROS) production, i
Autor:
Tara L. Davis, Hsiau-Wei Lee, Chelsea Gustafson, Hande Asimgil, Haiyan Xu, Christopher Ahlbach, Alicia K. Michael, Owen L. Williams, Carrie L. Partch, Nicole C. Parsley, Andrew C. Liu
Publikováno v:
Molecular cell. 66(4)
The C-terminal transactivation domain (TAD) of BMAL1 (brain and muscle ARNT-like 1) is a regulatory hub for transcriptional coactivators and repressors that compete for binding and, consequently, contributes to period determination of the mammalian c