Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Michaela Lang"'
Autor:
Michaela Lang, Šárka Pospíšilová, Christoph Gasche, Melanie Borgmann, Boris Tichy, Maren Pflueger, Vineeta Khare, Harald Hundsberger, Alex Lyakhovich, Rayko Evstatiev, Gloria Luciani, Christoph Campregher, Kyle Dammann
Publikováno v:
Biochemical Pharmacology
Graphical abstract (a) PAK1 orchestrates mesalamine activity, (b) mesalamine inhibits PAK1; increases membranous E-cadherin and β-catenin; modulates cell adhesion
Mesalamine (5-ASA) is widely used for the treatment of ulcerative colitis, a remi
Mesalamine (5-ASA) is widely used for the treatment of ulcerative colitis, a remi
Autor:
Michaela Lang, Volker Uhl, Nicole-Claudia Meisner, Jan-Marcus Seifert, Roger Benoit, Armin Widmer, Hubert Gstach, Manfred Auer, Roman Bauer, Martin Hintersteiner, Torsten Schindler
Publikováno v:
Journal of Molecular Biology. 386:435-450
Posttranscriptional regulation and RNA metabolism have become central topics in the understanding of mammalian gene expression and cell signalling, with the 3' untranslated region emerging as the coordinating unit. The 3' untranslated region trans-ac
Autor:
Michaela Lang, Thomas Gawlowski, Ralph T. Schermuly, Baktybek Kojonazarov, Renate B. Pilz, Alexander Pfeifer, Shunhui Zhuang, Ana Kilić, Thuan Diep, Gerry R. Boss, Raphaela Schwappacher
Publikováno v:
The Journal of biological chemistry. 288(23)
Pulmonary arterial hypertension (PAH) is a progressive, usually fatal disease with abnormal vascular remodeling. Pulmonary artery smooth muscle cells (PASMCs) from PAH patients are hyperproliferative and apoptosis-resistant and demonstrate decreased
Autor:
Christoph Campregher, Gerald Schmid, Franziska Ferk, Siegfried Knasmüller, Vineeta Khare, Benedikt Kortüm, Kyle Dammann, Michaela Lang, Theresa Scharl, Andreas Spittler, Andres I Roig, Jerry W Shay, Christopher Gerner, Christoph Gasche
Publikováno v:
PLoS ONE
PLoS ONE, Vol 7, Iss 11, p e50541 (2012)
PLoS ONE, Vol 7, Iss 11, p e50541 (2012)
Background/aimElevated microsatellite instability at selected tetranucleotide repeats (EMAST) is a genetic signature in certain cases of sporadic colorectal cancer and has been linked to MSH3-deficiency. It is currently controversial whether EMAST is
Autor:
Christoph Gasche, Kyle Dammann, Alex Lyakhovich, Vineeta Khare, Michaela Lang, Christoph Campregher
Publikováno v:
Biochemical Pharmacology
Graphical abstract 5-ASA induces membranous retention of E-cadherin through remodeling of N-glycans. Stabilization of E-cadherin at cell, contacts results in increased intercellular adhesion restricting tumor progression or restoring epithelial integ