Zobrazeno 1 - 10
of 129
pro vyhledávání: '"Michael J. Welsh"'
Publikováno v:
The FASEB Journal. 33
Autor:
Robert R. Gilmont, Martin Bommer, James E. Goldman, Rainer Benndorf, Sahoko Hirano, Michael J. Welsh, Richard F. Ransom, Peter R. Jungblut
Publikováno v:
Cell Stress and Chaperones
When analyzing small stress proteins of rat and human tissues by electrophoretic methods followed by western blotting, and using the anti-HspB1/anti-HspB5 antibody clone 8A7, we unexpectedly found a protein with a molecular mass of ~44 kDa. On two-di
Autor:
Juthika Mandal, John A. Wemmie, Jamison J Ash, Austin C Stark, Jianyang Du, Daniel Grigsby, Zubayer Hossain Saad, Kritika Singh, Margaret P. Price, Rebecca J. Taugher, Michael J. Welsh
Publikováno v:
eLife
eLife, Vol 6 (2017)
eLife, Vol 6 (2017)
Attenuating the strength of fearful memories could benefit people disabled by memories of past trauma. Pavlovian conditioning experiments indicate that a retrieval cue can return a conditioned aversive memory to a labile state. However, means to enha
Publikováno v:
The Journal of Biological Chemistry
Background: Electrophysiological studies indicated that Cl− channel function of cystic fibrosis transmembrane conductance regulator (CFTR) can be coupled to adenylate kinase activity (ATP+AMP ⇆ 2 ADP). Results: CFTR catalyzes phosphoryl group tra
Autor:
Stephen J.H. Ashcroft, Olaf Pongs, A. Baumann, Andrew Grupe, Patrik Rorsman, Frances M. Ashcroft, Susan Kenna, John Sandblom, Christer Betsholtz, Per Olof Berggren, Michael J. Welsh
We have used the polymerase chain reaction (PCR) with primers against the S5 and S6 regions of voltage-gated K + channels to identify 8 different specific amplification products using poly(A) + RNA isolated from islets of Langerhans from obese hyperg
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0ba808b17ec49432710c4e32b16e7ce1
https://doi.org/10.1016/0014-5793(90)80719-y
https://doi.org/10.1016/0014-5793(90)80719-y
Autor:
Thomas O. Moninger, Michael J. Welsh, Biswa Choudhury, Ajit Varki, James D. McMenimen, David A. Stoltz, Lynda S. Ostedgaard, Philip H. Karp, Mark J. Hoegger, Xiao Xiao Tang
Cystic fibrosis (CF) disrupts respiratory host defenses, allowing bacterial infection, inflammation, and mucus accumulation to progressively destroy the lungs. Our previous studies revealed that mucus with abnormal behavior impaired mucociliary trans
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::266bc0f02f808bb53a33f3e202ca3b74
https://europepmc.org/articles/PMC4767348/
https://europepmc.org/articles/PMC4767348/
Autor:
Joseph Zabner, Ira Kurtz, Pablo Bringas, Michael L. Paine, Charles E. Smith, Antonio Nanci, Sanjeev K. Baniwal, Rodrigo S. Lacruz, Pierre Moffatt, Timothy G. Bromage, Michael J. Welsh, Eugene H. Chang
Publikováno v:
Journal of Cellular Physiology. 227:1776-1785
Transcellular bicarbonate transport is suspected to be an important pathway used by ameloblasts to regulate extracellular pH and support crystal growth during enamel maturation. Proteins that play a role in amelogenesis include members of the ABC tra
Autor:
Botond Banfi, David A. Stoltz, Joseph Zabner, Lakshmi Durairaj, Gideon K. D. Zamba, Alejandro A. Pezzulo, Michael J. Welsh, Yoko Nakano, Janice L. Launspach, Daniel Lorentzen, William M. Nauseef, Paul B. McCray
Publikováno v:
Free Radical Biology and Medicine. 50:1144-1150
A recently discovered enzyme system produces antibacterial hypothiocyanite (OSCN(-)) in the airway lumen by oxidizing the secreted precursor thiocyanate (SCN(-)). Airway epithelial cultures have been shown to secrete SCN(-) in a CFTR-dependent manner
Autor:
Rainer Benndorf, Adam D. Hoppe, Michael J. Welsh, Jody L. Martin, Patrick Vicart, Jean-Marc Fontaine, Serena Carra, Xiankui Sun, Cheryl A. DeGuzman, Jacques Landry, Stéphanie Simon
Publikováno v:
Cell stress & chaperones, 15(5), 567-582. SPRINGER
A number of missense mutations in the two related small heat shock proteins HspB8 (Hsp22) and HspB1 (Hsp27) have been associated with the inherited motor neuron diseases (MND) distal hereditary motor neuropathy and Charcot-Marie-Tooth disease. HspB8
Autor:
Peter M. Snyder, Michael J. Welsh, Daniel M. Collier, John A. Wemmie, Runping Wang, Xiang-ming Zha
Publikováno v:
Proceedings of the National Academy of Sciences. 106:3573-3578
The acid-sensing ion channel-1a (ASIC1a) is composed of 3 subunits and is activated by a decrease in extracellular pH. It plays an important role in diseases associated with a reduced pH and production of oxidants. Previous work showed that oxidants