Zobrazeno 1 - 10
of 194
pro vyhledávání: '"Louis, D."'
Autor:
Juan Diez, Sumitha Rajendrarao, Shadi A. Baajour, Praathibha Sripadhan, TImothy P. Spicer, Louis D. Scampavia, Dmitriy Minond
Publikováno v:
Cellular Physiology and Biochemistry, Vol 55, Iss 3, Pp 265-276 (2021)
Externí odkaz:
https://doaj.org/article/fb6336e0bc064043a032794a5dcf85af
Autor:
Shrikant Barot, Olivia J. Stephenson, Hari Priya Vemana, Anjali Yadav, Shraddha Bhutkar, Louis D. Trombetta, Vikas V. Dukhande
Publikováno v:
Biochem Pharmacol
Hepatocellular carcinoma (HCC) is one of the leading causes of cancer-related deaths. There is an urgent need for new targets to treat HCC due to limited treatment options and drug resistance. Many cancer cells are known to have high amount of glycog
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::107e75cc3e1aa4cb719e5466623c8402
https://europepmc.org/articles/PMC10039449/
https://europepmc.org/articles/PMC10039449/
Publikováno v:
Journal of dermatological science. 101(1)
Background Excessive UV radiation disrupts skin homeostasis by multiple mechanisms that extend beyond the simple erythema associated with sunburns including reduction of antioxidants, increased DNA damage, and impairment of skin immune responses. Rec
Autor:
Francisco J. Schopfer, Meaghan E. Killeen, Sonia R. Salvatore, Louis D. Falo, Bruce A. Freeman, Cara Donahue Carey, Laura K. Ferris, Alicia R. Mathers
Publikováno v:
Free Radical Biology and Medicine. 115:31-42
Endogenous electrophilic fatty acids mediate anti-inflammatory responses by modulating metabolic and inflammatory signal transduction and gene expression. Nitro-fatty acids and other electrophilic fatty acids may thus be useful for the prevention and
Autor:
Zohreh Gholizadeh Ghozloujeh, Cara Donahue Carey, Emrullah Korkmaz, Oleg E. Akilov, Louis D. Falo, Stephen C. Balmert
Publikováno v:
J Invest Dermatol
Skin-targeted drug delivery is broadly employed for both local and systemic therapeutics and is an important tool for discovery efforts in cutaneous biology. Recently, emerging technologies support efforts toward skin-targeted biocargo delivery for l
Autor:
Francisco J. Schopfer, Alicia R. Mathers, Tina L. Sumpter, Louis D. Falo, Meaghan E. Killeen, Bruce A. Freeman, Peng Wang, Laura K. Ferris
Publikováno v:
Redox Biology
Redox Biology, Vol 43, Iss, Pp 101987-(2021)
Redox Biology, Vol 43, Iss, Pp 101987-(2021)
Psoriasis is a chronic inflammatory skin disease with no cure. Although the origin of psoriasis and its underlying pathophysiology remain incompletely understood, inflammation is a central mediator of disease progression. In this regard, electrophili
Autor:
Z. G. Ghozloujeh, Emrullah Korkmaz, Tina L. Sumpter, Stephen C. Balmert, Louis D. Falo, Geza Erdos, Cara Donahue Carey
Publikováno v:
The Journal of Investigative Dermatology
Considerable progress has been made toward development of COVID-19 vaccines in the past year However, there is still a need for painless, self-administered, shelf-stable, and efficacious SARS-CoV-2 vaccines to enable sustainable immunization programs
Autor:
Carol Chen-Scarabelli, Hemang Patel, Giovanni Corsetti, Riccardo Raddino, Louis D. Saravolatz, Richard Knight, Francesco S. Dioguardi, Evasio Pasini, Jagat Narula, TM Scarabelli, Mara Gavazzoni, Gagan Sahni
Publikováno v:
EBioMedicine, Vol 21, Iss C, Pp 206-212 (2017)
EBioMedicine
EBioMedicine
Background Carfilzomib (CFZ) is a new proteasome inhibitor used for the treatment of multiple myeloma. Besides heart failure, angina and myocardial ischemia occurred following administration of CFZ, which is not contraindicated in patients with recen
Autor:
Vinicio A. de Jesus Perez, Manish J. Butte, Timothy M. Crombleholme, Swathi Balaji, Thomas N. Wight, Sukanta S. Bhattacharya, Sundeep G. Keswani, Xinyi Wang, Louis D. Le, Alice King, Chad M. Moles, Paul L. Bollyky, Kenneth W. Liechty
Publikováno v:
The FASEB Journal. 31:868-881
The cytokine IL-10 has potent antifibrotic effects in models of adult fibrosis, but the mechanisms of action are unclear. Here, we report a novel finding that IL-10 triggers a signal transducer and activator of transcription 3 (STAT3)-dependent signa
Autor:
Louis D. Falo, Emrullah Korkmaz
Publikováno v:
J Invest Dermatol
The activation of T helper 17 signaling plays a critical role in psoriasis pathogenesis, and systemically-administered IL-17 inhibitors are highly effective therapy for moderate-to-severe disease. We generated topically-delivered gene-regulating nano