Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Jessica L. Bell"'
Autor:
Ensieh M. Poursani, Daniele Mercatelli, Prahlad Raninga, Jessica L. Bell, Federica Saletta, Felix V. Kohane, Daniel P. Neumann, Ye Zheng, Jourdin R. C. Rouaen, Toni Rose Jue, Filip T. Michniewicz, Piper Schadel, Erin Kasiou, Maria Tsoli, Giuseppe Cirillo, Shafagh Waters, Tyler Shai-Hee, Riccardo Cazzoli, Merryn Brettle, Iveta Slapetova, Maria Kasherman, Renee Whan, Fernando Souza-Fonseca-Guimaraes, Linda Vahdat, David Ziegler, John G. Lock, Federico M. Giorgi, KumKum Khanna, Orazio Vittorio
Publikováno v:
Cell & Bioscience, Vol 13, Iss 1, Pp 1-19 (2023)
Abstract Background Metastatic cancer cells exploit Epithelial-mesenchymal-transition (EMT) to enhance their migration, invasion, and resistance to treatments. Recent studies highlight that elevated levels of copper are implicated in cancer progressi
Externí odkaz:
https://doaj.org/article/b17391f9a29d4891bcdc6914896812f8
Autor:
Richard R. Neubig, Andrew J. Haak, Scott D. Larsen, Jessica L. Bell, Elizabeth R. Lawlor, Monique Verhaegen, Susan M. Wade
Publikováno v:
The FASEB Journal. 27
Autor:
Susan M. Wade, Andrew J. Haak, Paul D. Kirchhoff, Jessica L. Bell, Scott D. Larsen, Richard R. Neubig
Publikováno v:
Bioorganicmedicinal chemistry letters. 23(13)
CCG-1423 (1) is a novel inhibitor of Rho/MKL1/SRF-mediated gene transcription that inhibits invasion of PC-3 prostate cancer cells in a Matrigel model of metastasis. We recently reported the design and synthesis of conformationally restricted analogs
Autor:
Richard R. Neubig, Yihan Sun, Andrew J. Haak, Scott D. Larsen, Susan M. Wade, Jessica L. Bell
Publikováno v:
Beilstein Journal of Organic Chemistry
Beilstein Journal of Organic Chemistry, Vol 9, Iss 1, Pp 966-973 (2013)
Beilstein Journal of Organic Chemistry, Vol 9, Iss 1, Pp 966-973 (2013)
CCG-1423 and related analogues represent a new class of inhibitors of Rho/MKL1/SRF-mediated gene transcription, a pathway that has been implicated in both cancer and fibrosis. The molecular target for these compounds is unknown. To facilitate its ide
Autor:
Jessica Koach, Belamy B. Cheung, Jessica L. Bell, A Malyukova, Michael W. Parker, Jessica K. Holien, Maria Kavallaris, Glenn M. Marshall
Publikováno v:
PLoS ONE
PLoS ONE, Vol 7, Iss 5, p e37470 (2012)
PLoS ONE, Vol 7, Iss 5, p e37470 (2012)
The TRIM family of proteins is distinguished by its tripartite motif (TRIM). Typically, TRIM proteins contain a RING finger domain, one or two B-box domains, a coiled-coil domain and the more variable C-terminal domains. TRIM16 does not have a RING d
Autor:
Scott D. Larsen, Susan M. Wade, Andrew J. Kocab, Nicole L. Harzdorf, Jessica L. Bell, H. D. Hollis Showalter, Richard R. Neubig, Jenny G. Ryu, Chris R. Evelyn
Publikováno v:
Bioorganicmedicinal chemistry letters. 20(2)
We recently identified bis(amide) CCG-1423 (1) as a novel inhibitor of RhoA/C-mediated gene transcription that is capable of inhibiting invasion of PC-3 prostate cancer cells in a Matrigel model of metastasis. An initial structure-activity relationsh
Autor:
Belamy B. Cheung, Michelle Lee, Murray D. Norris, Joanne Yan, Deborah A. Zajchowski, Glenn M. Marshall, Andrew Bohlken, Jessica L. Bell, Maria Kavallaris, Michelle Haber, Wayne Thomas, Hsiao-Lai Liu, Ben Roediger, Anna Raif, Anne Poljak, Stewart A. Smith
Publikováno v:
The Journal of biological chemistry. 281(26)
Retinoic acid (RA) induces growth arrest, cell death, and differentiation in many human cancer cells in vitro and has entered routine clinical use for the treatment of several human cancer types. One mechanism by which cancer cells evade retinoid-ind