Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Giuseppe Cirillo"'
Autor:
Matteo Brindisi, Manuela Curcio, Luca Frattaruolo, Giuseppe Cirillo, Antonella Leggio, Vittoria Rago, Fiore Pasquale Nicoletta, Anna Rita Cappello, Francesca Iemma
Publikováno v:
International Journal of Biological Macromolecules. 221:1491-1503
DOX-loaded nanoparticles able to actively target CD44-receptors and respond to redox stimuli were proposed as non-conventional chemotherapeutic strategy in breast cancer. A covalent conjugate of human serum albumin and hyaluronic acid was prepared an
Autor:
Orazio Vittorio, Daniele Mercatelli, Federico M. Giorgi, David S. Ziegler, Federica Saletta, Filip Michniewicz, Toby Trahair, Jourdin R. C. Rouaen, Rehana V. Hewavisenti, Giuseppe Cirillo
Copper is an essential transition metal frequently increased in cancer known to strongly influence essential cellular processes. Targeted therapy protocols utilizing both novel and repurposed drug agents initially demonstrate strong efficacy, before
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::00309c777502ec7596457ff88496312d
http://hdl.handle.net/11585/831844
http://hdl.handle.net/11585/831844
Autor:
Angel Concheiro, Carmen Alvarez-Lorenzo, Francesca Iemma, Manuela Curcio, Giuseppe Cirillo, Luis Diaz-Gomez
Publikováno v:
European Journal of Pharmaceutics and Biopharmaceutics. 117:324-332
pH/redox dual-responsive nanogels (DEX-SS) were prepared by precipitation polymerization of methacrylated dextran (DEXMA), 2-aminoethylmethacrylate (AEMA) and N,N'-bis(acryloyl)cystamine (BAC), and then loaded with methotrexate (MTX). Nanogels were s
Autor:
Liron Berger, Silke Hampel, Martina Giannaccini, Matteo Battaglini, Vittoria Raffa, Luciana Dente, Orazio Vittorio, Giuseppe Cirillo, Nicoletta di Leo
Publikováno v:
European Journal of Pharmaceutics and Biopharmaceutics. 114:1-10
We validated the anticancer potential of a nanoformulation made by (+)-catechin, gelatin and carbon nanotubes in terms of inhibition of cancer cell proliferation, migration and associated neo-angiogenesis. Gelatin was selected to stabilize the catech
Autor:
Francesca Iemma, Manuela Curcio, Umile Gianfranco Spizzirri, Giuseppe Cirillo, Alessandra Vacca, Elisabetta Ferretti, Zein Mersini Besharat, Giuseppina Catanzaro, Luana Abballe, Nevio Picci
Publikováno v:
International Journal of Pharmaceutics. 517:168-174
Redox-responsive nanoparticles were synthesized by desolvation of bovine serum albumin followed by disulfide-bond crosslinking with N , N ʹ-Bis (acryloyl) cystamine. Dynamic light scattering and transmission electron microscopy studies revealed sphe
Autor:
Eugene M. H. Yee, Giuseppe Cirillo, Miriam B. Brandl, David StC Black, Orazio Vittorio, Naresh Kumar
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 7 (2019)
Frontiers in Bioengineering and Biotechnology
Frontiers in Bioengineering and Biotechnology
Phenoxodiol, an isoflavene anti-tumor agent, was conjugated on the polysaccharide dextran using immobilized laccase as biocatalyst. The success of the enzymatic conjugation was determined by UV-vis spectrophotometry and its functionalization degree w
Publikováno v:
Polymer Chemistry. 7:1529-1544
Well-known for their antioxidant properties, polyphenols are naturally occurring compounds containing one or more phenol groups. A high dietary intake of polyphenols has been linked to a reduced incidence of a number of diseases, including cancer, ca
Autor:
Manuela Curcio, Nevio Picci, Giuseppe Cirillo, Umile Gianfranco Spizzirri, Francesca Iemma, Fiore Pasquale Nicoletta
Publikováno v:
Reactive and Functional Polymers. 83:62-69
A new approach for the synthesis of hydrogel films with thermo-sensitive enzymatic activity is reported. Pepsin (PEP) was covalently immobilized on thermo-responsive hydrogels by radical polymerization in the presence of N-isopropylacrylamide and pol
Publikováno v:
J. Mater. Chem. B. 2:7000-7008
The use of DNA-based therapeutics requires efficient delivery systems to transport the DNA to their place of action within the cell. To accomplish this, we investigated multiwalled carbon nanotubes (pristine MWCNT, p-MWCNT) functionalized with hydrox
Autor:
Giuseppe Cirillo, Nevio Picci, Manuela Curcio, Orazio Vittorio, Francesca Iemma, Donatella Restuccia, Umile Gianfranco Spizzirri, Francesco Puoci
Publikováno v:
Critical Reviews in Food Science and Nutrition. 56:326-337
In recent years, antioxidants have gained great importance because of their potential use in food, pharmaceutical, and cosmetic industries. This interest is rooted in the cumulative evidence connecting active oxygen and free radicals with numerous hu