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pro vyhledávání: '"Dustin Thomas"'
Non-muscle myosin II (NMII) is a conserved force-producing cytoskeletal enzyme with important but poorly understood roles in cell migration. To investigate myosin heavy chain (MHC) phosphorylation roles in 3D migration, we expressed GFP-tagged NMIIA
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::777a876c08c6bf1a769e34436d8f1f52
https://europepmc.org/articles/PMC5336147/
https://europepmc.org/articles/PMC5336147/
Publikováno v:
Neuroscience Letters. 450:206-210
Zinc dyshomeostasis in brain might be involved in the pathogenesis of a series of brain diseases such as Alzheimer's disease and stroke. It is essential that the level of intracellular free Zn2+ in neurons is tightly controlled to maintain a narrow w
Publikováno v:
Journal of Neurochemistry. 107:1304-1313
Zinc dyshomeostasis in brain might be involved in the pathogenesis of brain diseases such as Alzheimer's disease and stroke. Resting neurons tightly regulate and maintain low to subnanomolar levels of intracellular free Zn2+, but mechanisms of normal
Autor:
Charles P. Fontaine, Robert A. Colvin, Ashley I. Bush, Dustin Thomas, Kazuya Kikuchi, Irene Volitakis, William R. Holmes
Publikováno v:
American journal of physiology. Cell physiology. 294(3)
To understand the mechanisms of neuronal Zn2+homeostasis better, experimental data obtained from cultured cortical neurons were used to inform a series of increasingly complex computational models. Total metals (inductively coupled plasma-mass spectr
Autor:
Dustin Thomas, Tetsuo Nagano, Charles P. Fontaine, Robert A. Colvin, Kazuya Kikuchi, Tomoya Hirano
Publikováno v:
Archives of biochemistry and biophysics. 442(2)
Using both ZnAF-2F (a Zn2+ specific fluorophore) and 65Zn2+, we determined the rate of transporter mediated Zn2+ influx (presumably mediated by the SLC39A1 gene product, protein name hZIP1) under steady state conditions and studied the effects of ext
Publikováno v:
Blood. 112:3661-3661
Combining drugs that inhibit different antiapoptotic pathways will be useful in overcoming drug resistance in multiple myeloma (MM). Since histone deacetylase inhibitors (HDACi) affect multiple pathways of cancer progression by relaxing chromatin; th
Publikováno v:
Cytokine. 43:286