Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Caroline M. Milner"'
Autor:
Caroline M. Milner, Anthony J. Day, Holly L. Birchenough, Alexander W.W. Langford-Smith, Jan J. Enghild, Clair Baldock, Cay M. Kielty, David Briggs, Thomas A. Jowitt
Publikováno v:
The Journal of Biological Chemistry
The journal of biological chemistry 295(16), 5278-5291 (2020). doi:10.1074/jbc.RA119.011916
Briggs, D C, Langford-Smith, A W W, Birchenough, H L, Jowitt, T A, Kielty, C M, Enghild, J J, Baldock, C, Milner, C M & Day, A J 2020, ' Inter-α-inhibitor heavy chain-1 has an integrin-like 3D structure mediating immune regulatory activities and matrix stabilization during ovulation ', The Journal of Biological Chemistry, vol. 295, no. 16, pp. 5278-5291 . https://doi.org/10.1074/jbc.RA119.011916, https://doi.org/10.1074/jbc.RA119.011916
The journal of biological chemistry 295(16), 5278-5291 (2020). doi:10.1074/jbc.RA119.011916
Briggs, D C, Langford-Smith, A W W, Birchenough, H L, Jowitt, T A, Kielty, C M, Enghild, J J, Baldock, C, Milner, C M & Day, A J 2020, ' Inter-α-inhibitor heavy chain-1 has an integrin-like 3D structure mediating immune regulatory activities and matrix stabilization during ovulation ', The Journal of Biological Chemistry, vol. 295, no. 16, pp. 5278-5291 . https://doi.org/10.1074/jbc.RA119.011916, https://doi.org/10.1074/jbc.RA119.011916
Inter-α-inhibitor is a proteoglycan essential for mammalian reproduction and also plays a less well-characterized role in inflammation. It comprises two homologous "heavy chains" (HC1 and HC2) covalently attached to chondroitin sulfate on the bikuni
Autor:
David J. Mahoney, Benedict M. Sattelle, Andrew Almond, Paul L. DeAngelis, Caroline M. Milner, Douglas P. Dyer, Anthony J. Day, Charles D. Blundell, David Briggs, Victoria A. Higman, Dixy E. Green
Publikováno v:
The Journal of Biological Chemistry
Background: The polysaccharide hyaluronan is organized through interactions with the protein TSG-6 during inflammation and ovulation. Results: NMR spectroscopy on TSG-6 in the presence of defined sugars provided restraints that allowed modeling of a
Publikováno v:
Biochemical Society Transactions. 34:446-450
TSG-6 is a multifunctional protein that is up-regulated in many pathological and physiological contexts, where it plays important roles in inflammation and tissue remodelling. For example, it is a potent inhibitor of neutrophil migration and can modu
Autor:
David J. Mahoney, Mark J. Forster, Eric Fries, Caroline M. Milner, Charles D. Blundell, Barbara Mulloy, Anthony J. Day
Publikováno v:
Journal of Biological Chemistry. 280:27044-27055
TSG-6, the secreted product of tumor necrosis factor-stimulated gene-6, is not constitutively expressed but is up-regulated in various cell-types during inflammatory and inflammation-like processes. The mature protein is comprised largely of contiguo
Autor:
David J. Mahoney, Gavin C. Jones, Simon J. Clark, Jason D. Whittle, Anthony J. Day, Robert D. Short, Barbara Mulloy, Caroline M. Milner, David J. Buttle
Publikováno v:
Analytical Biochemistry. 330:123-129
The interaction of heparan sulfate (HS) with specific proteins facilitates a wide range of fundamental biological processes including cellular proliferation and differentiation, tissue homeostasis, and viral pathogenesis. This multiplicity of functio
Publikováno v:
Tissue Antigens. 56:38-44
The three major histocompatibility complex (MHC)-linked hsp70s have been screened for variation in their 28 kDa C-terminal regions by direct nucleotide sequencing of the corresponding DNA fragments. No amino acid variation was detected in the major h
Publikováno v:
Glycobiology. 7:975-986
The Neu1 locus, in the S region of the murine histocompatibility-2 complex, regulates the sialic acid content of several liver lysosomal enzymes. Three alleles, Neu1a, Neu1b, and Neu1c, have been described on the basis of differential sialylation of
Autor:
Caroline M. Milner, R D Campbell
Publikováno v:
ResearcherID
The class III region of the human major histocompatibility complex spans approx. 1.1 Mbp on the short arm of chromosome 6 and is known to contain at least 36 genes. The complete nucleotide sequence of a 3.4 kb mRNA from one of these genes, G9a (or BA
Autor:
Anthony J. Day, John D. Sandy, Matthew C. Stewart, Marilyn S. Rugg, Y. Yoshihara, K. Nemoto, Fred R.T. Nelson, Caroline M. Milner, Arkady Margulis, Barbara Osborn, Anna Plaas
Publikováno v:
Osteoarthritis and cartilage. 16(11)
Summary Objective We have examined the occurrence of the inflammation-associated inter-alpha-trypsin inhibitor (IαI) components, bikunin, heavy chain (HC)1 and HC2 in normal cartilage and osteoarthritis (OA) cartilage and synovial fluids. Design/met
Autor:
Anthony J. Day, Dafna Benayahu, David J. Mahoney, Caroline M. Milner, Afsie Sabokbar, Guillaume Mabilleau, Katalin Mikecz, T. Ali, Anna Plaas
Publikováno v:
Journal of Biological Chemistry
Journal of Biological Chemistry, American Society for Biochemistry and Molecular Biology, 2008, 283 (38), pp.25952-25962. ⟨10.1074/jbc.M802138200⟩
The Journal of Biological Chemistry
Journal of Biological Chemistry, American Society for Biochemistry and Molecular Biology, 2008, 283 (38), pp.25952-25962. ⟨10.1074/jbc.M802138200⟩
The Journal of Biological Chemistry
International audience; TSG-6 is an inflammation-induced protein that is produced at pathological sites, including arthritic joints. In animal models of arthritis, TSG-6 protects against joint damage; this has been attributed to its inhibitory effect
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b471a4394f347259c357d12950c12613
https://hal.univ-angers.fr/hal-03261996
https://hal.univ-angers.fr/hal-03261996