Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Ansuman T. Satpathy"'
Autor:
Joy A. Pai, Ansuman T. Satpathy
Publikováno v:
Nat Methods
T cells express T cell receptors (TCRs) composed of somatically recombined TCRα and TCRβ chains, which mediate recognition of major histocompatibility complex (MHC)-antigen complexes and drive the antigen-specific adaptive immune response to pathog
Autor:
Jo Anne Stratton, Sorana Morrissy, Nizar J. Bahlis, Weiqiang Zhou, Ansuman T. Satpathy, Sarthak Sinha, Hongkai Ji, Arzina Jaffer, Jeff Biernaskie
Publikováno v:
Genomics, Proteomics & Bioinformatics
Genomics, Proteomics & Bioinformatics, Vol 19, Iss 2, Pp 172-190 (2021)
Genomics, Proteomics & Bioinformatics, Vol 19, Iss 2, Pp 172-190 (2021)
How distinct transcriptional programs are enacted to generate cellular heterogeneity and plasticity, and enable complex fate decisions are important open questions. One key regulator is the cell’s epigenome state that drives distinct transcriptiona
Autor:
Mark Y. Jeng, Ansuman T. Satpathy, Howard Y. Chang, Maxwell R. Mumbach, Anne Lynn S. Chang, Jeffrey M. Granja
Publikováno v:
Journal of Investigative Dermatology. 139:605-614
The vast majority of polymorphisms for human dermatologic diseases fall in noncoding DNA regions, leading to difficulty interpreting their functional significance. Recent work using chromosome conformation capture technology in combination with chrom
Autor:
Yanyan Qi, Daniel Nachun, Ansuman T. Satpathy, Paul K. Crane, Myriam Fornage, Sudha Seshadri, Julia A. Belk, Oscar L. Lopez, Siddhartha Jaiswal, Claudia L. Satizabal, Joshua C. Bis, Joshua S. Weinstock, Alexa S. Beiser, Winnie Yao, Matthew Chrostek, Chloé Sarnowski, Pradeep Nataranjan, W. T. Longstreth, Sara Wirth, Eric B. Larson, Hind Bouzid, Max Jan, Bruce M. Psaty, Herra Ahmad, Thomas J. Montine, C. Dirk Keene, Alexander G. Bick, Lisa Ma
Publikováno v:
Blood. 138:5-5
Clonal hematopoiesis of indeterminate potential (CHIP) occurs when hematopoietic stem cells (HSCs) acquire a mutation, most commonly a null variant in TET2 or DNMT3A, that confers a selective advantage. Blood cancers may result if additional cooperat
Autor:
Jimmy K. Guo, Ansuman T. Satpathy, Yanyan Qi, Paul A. Khavari, M. Ryan Corces, Maninjay K. Atianand, Ryan A. Flynn, Bryan H. Louie, William J. Greenleaf, Howard Y. Chang, Steven E. Artandi, Jeffrey M. Granja, Katherine A. Fitzgerald, Adam J. Rubin, Zhaozhao Jiang, Caitlin M. Roake, Maxwell R. Mumbach, David Gennert, Shadi Shams
Publikováno v:
Nature methods. 16(6)
Modular domains of long non-coding RNAs can serve as scaffolds to bring distant regions of the linear genome into spatial proximity. Here, we present HiChIRP, a method leveraging bio-orthogonal chemistry and optimized chromosome conformation capture
Autor:
Kristy L. Weber, Howard Y. Chang, Eric Lancaster, Yangbing Zhao, Wei-Ting Hwang, Ansuman T. Satpathy, Tina Matlawski, Joseph A. Fraietta, Edward A. Stadtmauer, Anne Lamontagne, Megan M. Suhoski, Vanessa E. Gonzalez, Gabriela Plesa, Regina M. Young, Elizabeth O. Hexner, Anne Chew, Christopher L. Nobles, Joanne Shea, Stephanie Desjardins, Frederic D. Bushman, January Salas-Mckee, J. Joseph Melenhorst, Don L. Siegel, Carl H. June, Avery L. Gaymon, Adam D. Cohen, Andrew D. Fesnak, Patricia A. Mangan, Simon F. Lacey, Matthew O'Rourke, Amanda Cervini
Publikováno v:
Blood. 134:49-49
Background: Autologous T cells genetically modified with a lentiviral vector to express affinity-enhanced T cell receptors (TCR) or chimeric antigen receptors have shown great promise for the treatment of cancer. NY-ESO-1 is a cancer testis antigen w
Autor:
Howard Y. Chang, Maxwell R. Mumbach, Anshul Kundaje, Maya Kasowski, Kathleen S. Montine, Viviana I. Risca, Beijing Wu, Ansuman T. Satpathy, Alexandro E. Trevino, M. Ryan Corces, Thomas J. Montine, Arwa Kathiria, Adam J. Rubin, Peyton Greenside, Paul A. Khavari, Emily G. Hamilton, William J. Greenleaf, Nicholas A Sinnott-Armstrong, Sam Vesuna, Ava C. Carter, Lisa A. Orloff, Seung Woo Cho
Publikováno v:
Nature methods. 14(10)
We present Omni-ATAC, an improved ATAC-seq protocol for chromatin accessibility profiling that works across multiple applications with substantial improvement of signal-to-background ratio and information content. The Omni-ATAC protocol enables chrom
Autor:
Howard Y. Chang, Rajarshi P. Ghosh, Seung Woo Cho, Ying Shen, Jan Liphardt, William J. Greenleaf, Ulrike M. Litzenburger, Jennifer A. Doudna, Ansuman T. Satpathy, Jason D. Buenrostro, Xingqi Chen, Alexandra East-Seletsky, Ava C. Carter, Will E Draper
Publikováno v:
Nature methods. 13(12)
Spatial organization of the genome plays a central role in gene expression, DNA replication, and repair. But current epigenomic approaches largely map DNA regulatory elements outside of the native context of the nucleus. Here we report assay of trans
Autor:
Paul A. Khavari, Howard Y. Chang, Ansuman T. Satpathy, Adam J. Rubin, William J. Greenleaf, Muthukumar Ramanathan, K. Parker
Publikováno v:
Journal of Investigative Dermatology. 139:S63
Autor:
S. Reddy, Duy C. Tran, Anne Lynn S. Chang, Mark Y. Jeng, John G.D. Cannon, Shaoying Li, A. Colevas, Kavita Y. Sarin, Ansuman T. Satpathy, K. Yost, Kerri E. Rieger
Publikováno v:
Journal of Investigative Dermatology. 139:S92