Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Alice Zhang"'
Autor:
Junken Aoki, Darlaine Pétrin, Alice Zhang, Terence E. Hébert, Dominic Devost, Rory Sleno, Asuka Inoue, Kyla Bourque, Yuji Shinjo
Publikováno v:
Journal of Biological Chemistry. 292:12139-12152
G protein-coupled receptors (GPCRs) are conformationally dynamic proteins transmitting ligand-encoded signals in multiple ways. This transmission is highly complex and achieved through induction of distinct GPCR conformations, which preferentially dr
Autor:
Dominic Devost, Alice Zhang, Rakan Okde, Terence E. Hébert, Junken Aoki, Yuji Shinjo, Rory Sleno, Asuka Inoue, Darlaine Pétrin
Publikováno v:
Journal of Biological Chemistry. 292:5443-5456
Here, we report the design and use of G protein-coupled receptor-based biosensors to monitor ligand-mediated conformational changes in receptors in intact cells. These biosensors use bioluminescence resonance energy transfer with Renilla luciferase (
Autor:
Gabriel R. Linares, Justin K. Ichida, Yingxiao Shi, Brandon B Ge, Yichen Li, Jacob Komberg, R. Jeroen Pasterkamp, Davide Trotti, Valerie Hennes, Leonard H. van den Berg, Nicole Koutsodendris, Jason A. Chen, Kaitlin P. Sandor, Vamshidhar R. Vangoor, Louise Menendez, Amy R. Nelson, Michael E. Ward, Tze-Yuan Cheng, Yaoming Wang, Phillip E. Woolwine, Wen-Hsuan Chang, Ketharini Senthilkumar, Kim A. Staats, Mickey Huang, Carina Seah, Alice Zhang, Chris Grunseich, Esther Y. Son, Eric Hendricks, Michael J. Cowan, Paul R. August, Kassandra Kisler, Shih Jong J. Lee, Marcelo P. Coba, Shu Ting Hung, Shaoyu Lin, Brent Wilkinson, N. Wisniewski, Berislav V. Zlokovic, Tohru Sugawara, T. Grant Belgard, Victor Hanson-Smith, Xinmei Wen
Publikováno v:
Nature Medicine, 24(3), 313. Nature Publishing Group
An intronic GGGGCC repeat expansion in C9ORF72 is the most common cause of amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD), but the pathogenic mechanism of this repeat remains unclear. Using human induced motor neurons (iMNs), w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6a7b18c3fd3677e0457e409e74f97ed0
https://dspace.library.uu.nl/handle/1874/364200
https://dspace.library.uu.nl/handle/1874/364200
Autor:
Andrew Ippoliti, Xiaofei Yan, Bradley Morganstern, Gil Y. Melmed, Jonathan Pourmorady, Dermot P.B. McGovern, Minh Nguyen, Sundip S. Karsan, Alice Zhang, Phillip Fleshner, Eric A. Vasiliauskas, Stephan R. Targan, David Q. Shih
Publikováno v:
Gastroenterology. 148:S-702
INTRODUCTION: The prevalence of inflammatory bowel disease (IBD) is increasing globally whilst genetic factors account for only a small portion of overall disease variance. Accumulating evidence has highlighted the importance of epigenetic regulation