Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Ai-Yun Peng"'
Autor:
Guoping Peng, Juan Tang, Li-qun Rao, Lan Yang, Huan-Zhi Yang, Jin-Jun Chen, Ai-Yun Peng, Chen Zhang, Qi-Ming Wang, Xian-Wen Zhang, Hua Yang
Publikováno v:
Journal of Asian Natural Products Research. 21:462-475
Poria cocos (P. cocos) polysaccharides (PCPs) are used to improve immunity and possess antitumor activities. We compared three cultivars of P. cocos (5.78, XJ 28 and JHYH) PCP contents. Then we determined that malZ, galA, SORD, gnl and bglX are key e
Publikováno v:
Organic & Biomolecular Chemistry. 16:6783-6790
A systematic study on the iodine-mediated phosphoramidation reaction of amines and trialkyl phosphites was conducted, which not only disclosed the factors affecting the reaction but also revealed that it could proceed smoothly in CH2Cl2 at room tempe
Publikováno v:
Organic & Biomolecular Chemistry. 15:7396-7403
The bromocyclization of 4-aryl-3-butenylphosphonic acid monoesters could proceed smoothly and rapidly in CH3CN with 1.2 equiv. of NBS in the presence of 0.02 equiv. of DABCO at room temperature, giving exclusively the six-membered ring bromophostones
Publikováno v:
European Journal of Medicinal Chemistry. 74:751-758
A series of phosphorylated flavonoids were synthesized and investigated in vitro as inhibitors of pancreatic cholesterol esterase (CEase) and acetylcholinesterase (AChE). The results showed that most of the synthesized compounds exhibited nanomolar p
Publikováno v:
Journal of Fluorine Chemistry. 151:58-62
An efficient and general Suzuki coupling reaction between 2-phosphonylaryl nonaflates and ( E )-1-alkenylboronic pinacol esters using Pd(OAc) 2 /PPh 3 as catalysts, K 2 CO 3 as base and DMF as solvent has been developed. This strategy allows for conv
Publikováno v:
Journal of Fluorine Chemistry. 132:982-986
Iodide salt, such as NaI, KI or n -Bu 4 NI (TBAI), rather than bromide or chloride salt, was found to play a key role in the Pd(0)-catalyzed Heck reaction of aryl nonaflates and terminal alkenes. In the presence of PdCl 2 (PPh 3 ) 2 , NaI or TBAI in
Publikováno v:
Organicbiomolecular chemistry. 12(29)
A series of phosphaisocoumarin amidates were synthesized for the first time via DIBAL-H-mediated direct amidation of phosphaisocoumarin esters under mild conditions in good to excellent yields. The present reaction showed high selectivity. In each ca
Publikováno v:
Chemico-biological interactions. 204(2)
We have recently synthesized a series of phosphorylated flavonoids and identified some of them as potent inhibitors of pancreatic cholesterol esterase (CEase) with excellent selectivity for CEase over acetylcholinesterase (AChE). In the present paper
Publikováno v:
European journal of medicinal chemistry. 45(5)
Due to the importance of pancreatic cholesterol esterase (CEase) as a potential target in atherosclerosis and for the development of hypocholesterolemic agents, there are increasing interests in designing and synthesizing CEase inhibitors. In the pre
Autor:
Yi-Xiang Ding, Ai-Yun Peng
Publikováno v:
ChemInform. 37
A series of 4-halophosphaisocoumarins were prepared with high regioselectivity in good to excellent yields under mild conditions by the reaction of 2-(1-alkynyl)phenylphosphonic acid diesters with I 2 in CHCl 3 or ICl in CH 2 Cl 2 , or by the reactio