Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Paul R. August"'
Publikováno v:
Journal of Bacteriology. 176:4448-4454
Two genes (mcrA and mcrB) from Streptomyces lavendulae that together confer resistance to mitomycin C were identified. This DNA appears to comprise a polycistronic operon with a drug-inducible leaderless mRNA. The deduced amino acid sequence of mcrA
Autor:
Chun-Gyu Kim, C. Richard Hutchinson, Li Tang, Tin-Wein Yu, Matthew P. Taylor, Yeo J. Yoon, Paul R. August, Heinz G. Floss, Sandra Ning, Dietmar Hoffmann, Rolf Müller, Xiaohong Zhang
Publikováno v:
Chemistrybiology. 5(2)
Background: The ansamycin class of antibiotics are produced by various Actinomycetes. Their carbon framework arises from the polyketide pathway via a polyketide synthase (PKS) that uses an unusual starter unit. Rifamycin (rif), produced by Amycolatop