Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Suzette Girgis"'
Autor:
Diana Cortes-Selva, Tineke Casneuf, Deeksha Vishwamitra, Sarah Stein, Tatiana Perova, Sheri Skerget, Elena Ramos, Laure van Steenbergen, Dries De Maeyer, Rengasamy Boominathan, Onsay Lau, Cuc Davis, Arnob Banerjee, Tara Stephenson, Clarissa M. Uhlar, Rachel Kobos, Jenna D. Goldberg, Lixia Pei, Danielle Trancucci, Suzette Girgis, Shun Xin Wang Lin, Liviawati S. Wu, Philippe Moreau, Saad Usmani, Nizar Jacques Bahlis, Niels WCJ Van De Donk, Raluca Verona
Publikováno v:
Blood. 140:241-243
Autor:
Xin Miao, Liviawati S. Wu, Shun Xin Wang Lin, Yan Xu, Yang Chen, Yuki Iwaki, Rachel Kobos, Tara Stephenson, Kristy Kemmerer, Clarissa M. Uhlar, Arnob Banerjee, Jenna D. Goldberg, Danielle Trancucci, Raluca Verona, Lixia Pei, Yaming Su, Daniele Ouellet, Alfred L. Garfall, Amrita Y. Krishnan, Saad Usmani, Suzette Girgis, Honghui Zhou
Publikováno v:
Blood. 140:4382-4383
Autor:
Amrita Y. Krishnan, Salomon Manier, Evangelos Terpos, Saad Usmani, Josephine Khan, Rachel Pearson, Suzette Girgis, Yue Guo, Dana McAleer, Yunsi Olyslager, Tobias Kampfenkel, Niels W.C.J. van de Donk
Publikováno v:
Blood. 140:10148-10149
Autor:
Marie-Emilie Willemin, Shun Xin Wang Lin, Loeckie De Zwart, Liviawati S. Wu, Xin Miao, Raluca Verona, Arnob Banerjee, Baolian Liu, Rachel Kobos, Ming Qi, Daniele Ouellet, Jenna D. Goldberg, Suzette Girgis
Publikováno v:
Blood. 140:7253-7254
Autor:
Clarissa M. Uhlar, Jesús F. San-Miguel, Lotfi Benboubker, Saad Z. Usmani, Maria-Victoria Mateos, Alfred L. Garfall, Hareth Nahi, Rachel Kobos, Philippe Moreau, Rian Van Rampelbergh, Britta Besemer, Amrita Krishnan, Lionel Karlin, Jenna D. Goldberg, Laura Rosiñol, Suzette Girgis, Joaquin Martinez-Lopez, Nizar J. Bahlis, Niels W.C.J. van de Donk, Ajay K. Nooka, Albert Oriol, Lixia Pei, Thomas Martin, Arnob Banerjee, Raluca Verona, Yunsi Olyslager, Mindy Jaffe, Ajai Chari, Danielle Trancucci, Surbhi Sidana, Tara Stephenson, Rakesh Popat
Publikováno v:
Blood. 138:896-896
Introduction: Teclistamab (JNJ-64007957) is a T-cell redirecting, bispecific IgG4 antibody that targets both B-cell maturation antigen (BCMA) and CD3 receptors to induce T-cell mediated cytotoxicity of BCMA-expressing myeloma cells. Teclistamab is un
Autor:
Paula Rodriguez-Otero, Amrita Krishnan, Brandi Hilder, Elham Askari, Xuewen Ma, Shiyi Yang, Ajai Chari, Jenna D. Goldberg, Luciano J. Costa, Maria-Victoria Mateos, Suzette Girgis, Monique C. Minnema, Jesus G. Berdeja, Niels W.C.J. van de Donk, Jeffery S. Russell, Albert Oriol, Raluca Verona
Publikováno v:
Blood. 138:158-158
Introduction: Despite recent advances in treatment, patients with multiple myeloma (MM) continue to relapse. G protein-coupled receptor family C group 5 member D (GPRC5D) is a promising target for immunotherapy in patients with MM due to its high exp
Autor:
Brandi Hilder, Paula Rodriguez, Albert Oriol, Jesus G. Berdeja, Maria-Victoria Mateos, Suzette Girgis, Jeffery S. Russell, Raluca Verona, Thomas J. Prior, Monique C. Minnema, Ajai Chari, Niels W.C.J. van de Donk, Elham Askari, Amrita Krishnan, Jenna D. Goldberg
Publikováno v:
Blood. 136:40-41
Despite improved outcomes with current MM treatments, most patients (pts) will develop refractory disease, highlighting the need for novel treatments. GPRC5D is an orphan receptor whose transcript is highly expressed in primary MM cells but has gener
Autor:
Niels W.C.J. van de Donk, Tara Stephenson, Maria-Victoria Mateos, Laura Rosiñol, Hareth Nahi, Jenna D. Goldberg, Arnob Banerjee, Saad Z. Usmani, Albert Oriol Rocafiguera, Amrita Krishnan, Manisha Bhutani, Ajai Chari, Raluca Verona, Alfred L. Garfall, Jesús F. San-Miguel, Lixia Pei, Suzette Girgis
Publikováno v:
Blood. 136:27-27
Background: MM inevitably relapses and becomes refractory to treatment, representing a patient (pt) population with unmet needs. Teclistamab (JNJ-64007957) is a bispecific BCMA x CD3 antibody that induces T cell-mediated cytotoxicity against BCMA-exp
Autor:
Suzette Girgis, Brandi Hilder, Jennifer Smit, Brett Hanna, Yu-Nien Sun, Amarnath Sharma, Shoba Shetty, Homer Adams, Shun Xin Wang Lin, Jeffrey R. Infante, Jenna D. Goldberg, Arnob Banerjee, Tara Stephenson, Yusri Elsayed, Kodandaram Pillarisetti
Publikováno v:
Blood. 136:35-35
B cell maturation antigen (BCMA; CD269; TNFRSF17) is a surface receptor, expressed on benign and malignant plasma cells. The restricted expression of BCMA on B-cell lineage makes it an ideal target for multiple myeloma (MM) immunotherapy. BCMAxCD3 bi
Exploratory Pharmacokinetic/Pharmacodynamic and Tolerability Study of BCMAxCD3 in Cynomolgus Monkeys
Autor:
Eric Baldwin, Joyce Ford, Kodandaram Pillarisetti, Dan Weinstock, Kevin Bellew, Suzette Girgis, Trina Jiao, Chidozie Amuzie, Rebecca Grimme Watson, Shoba Shetty
Publikováno v:
Blood. 128:5668-5668
JNJ-64007957 is a bispecific antibody that binds to CD3 on T cells, and BCMA on plasma cells, and should induce T cell mediated killing of BCMA expressing malignant plasma cells. The objectives of this study were to characterize the tolerability of J