Zobrazeno 11 - 20
of 10 335
pro vyhledávání: ''
Autor:
Andreas Peter, Hans-Ulrich Häring, Martin Heni, Corinna Dannecker, Norbert Stefan, Andreas L. Birkenfeld, Julia Hummel, Robert Wagner, Andreas Vosseler, Andreas Fritsche
Publikováno v:
J. Clin. Endocrinol. Metab. 106, 1576-1584 (2021)
The Journal of Clinical Endocrinology and Metabolism
The Journal of Clinical Endocrinology and Metabolism
Context Pharmacological lowering of low-density lipoprotein (LDL) cholesterol potently reduces cardiovascular risk while concurrently increasing type 2 diabetes risk. Objective The aim of this study was to investigate the relationship between LDL cho
Publikováno v:
Current Medicinal Chemistry. 28:2048-2061
Prostate cancer is the second most common cancer affecting the male population all over the world. The existence of a correlation between lipid metabolism disorders and cancer of the prostate gland has been widely known for a long time. According to
Autor:
Helena Trevisan Schroeder, Paulo Ivo Homem de Bittencourt, Juliane da Silva Rossato, Sofia Pizzato Scomazzon, Claudia Vieira Marques, Lucila Ludmila Paula Gutierrez, João Roberto Fernandes
Publikováno v:
Biochimie. 182:37-50
Disruption of the intracellular lipid balance leading to cholesterol accumulation is one of the features of cells that participate in the development of atherosclerotic lesions. Evidence form our laboratory indicates that anti-inflammatory cyclopente
Autor:
Marta Casado, Liya Pi, Wei Wei, Minjie Chen, Xicui Sun, Qi Cao, Paloma Martín-Sanz, Carme Cucarella, Bin Ren
Publikováno v:
Alcohol (Fayetteville, N.Y.)
Digital.CSIC. Repositorio Institucional del CSIC
instname
Digital.CSIC. Repositorio Institucional del CSIC
instname
12 páginas, 5 figuras, 2 tablas
Purpose: A diet high in fat and ethanol often results in chronic metabolic disorder, hepatic steatosis, and liver inflammation. Constitutive hepatic cyclooxygenase-2 (COX-2) expression could protect from high fat
Purpose: A diet high in fat and ethanol often results in chronic metabolic disorder, hepatic steatosis, and liver inflammation. Constitutive hepatic cyclooxygenase-2 (COX-2) expression could protect from high fat
Autor:
Helena Panteliou Lima-Valassi, Luciana Ribeiro Montenegro, Berenice B. Mendonca, Madson Q. Almeida, Maria Candida Barisson Villares Fragoso, Chin Jia Lin, Antonio M. Lerario
Publikováno v:
Hormone and Metabolic Research. 53:124-131
3-Hydroxy-3-methylglutaryl coenzyme A reductase (HMGCR) is the rate-limiting enzyme of the mevalonate pathway, which generates cholesterol and non-sterol compounds such as isoprenoid, which are involved in key steps of tumorigenesis such as cell grow
Publikováno v:
Current Medical Science. 40:1099-1106
The effects of low ratio of n-6/n-3 polyunsaturated fatty acids (PUFA) have been clarified against atherosclerosis. Increasing evidence indicated that plant sterols (PS) have a significant cholesterol-lowering effect. This study explored the effects
Progression of chronic kidney disease in familial LCAT deficiency: a follow-up of the Italian cohort
Autor:
Tiziano Lucchi, Tiziana Sampietro, Giuliano Boscutti, Fabrizio Veglia, Alice Ossoli, Loreto Gesualdo, Marcello Arca, Laura Calabresi, Laura D'Erasmo, Chiara Pavanello
Publikováno v:
Journal of Lipid Research, Vol 61, Iss 12, Pp 1784-1788 (2020)
J Lipid Res
J Lipid Res
Familial LCAT deficiency (FLD) is a rare genetic disorder of HDL metabolism, caused by loss-of-function mutations in the LCAT gene and characterized by a variety of symptoms including corneal opacities and kidney failure. Renal disease represents the
Autor:
Shahid Ali Shah, Myeung Hoon Jo, Jun Sung Park, Sayed Ibrar Alam, Min Woo Kim, Myeong Ok Kim, Samreen Saleem, Rahat Ullah, Kamran Saeed, Jong Ryeal Hahm
Publikováno v:
Oxidative Medicine and Cellular Longevity, Vol 2020 (2020)
Oxidative Medicine and Cellular Longevity
Oxidative Medicine and Cellular Longevity
Alzheimer’s disease (AD) is a progressive neurodegenerative disorder typified by several neuropathological features including amyloid-beta (Aβ) plaque and neurofibrillary tangles (NFTs). Cholesterol retention and oxidative stress (OS) are the majo
Autor:
Xinrui Zhao, Yuexin Jin, Zhongmin Tian, Yanan Ouyang, Xuewei Zheng, Pengfei Yang, Lan Chen, Li Zeng, Meng Chen
Publikováno v:
Biochemical and Biophysical Research Communications. 533:188-194
Aims Dahl salt-sensitive (SS) rats develop similar prediabetes lesion characteristics, such as impaired glucose tolerance (IGT), when compared with the salt resistant rat. In this study, we evaluate the risk of high glucose intake during prediabetes
Autor:
Benjamin M. Abraham, Felix Zhou, Edward A. Fisher, Johannes von Lintig, Ivan Pinos, Jaume Amengual, Tessa J. Barrett, Xiaoyun Wu
Publikováno v:
Journal of Lipid Research, Vol 61, Iss 11, Pp 1491-1503 (2020)
J Lipid Res
J Lipid Res
Atherosclerosis is characterized by the pathological accumulation of cholesterol-laden macrophages in the arterial wall. Atherosclerosis is also the main underlying cause of CVDs, and its development is largely driven by elevated plasma cholesterol.