Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Mariano Severgnini"'
Autor:
Matthew S. Davids, Robert J. Soiffer, Emma S. Hathaway, F. Stephen Hodi, Pavan Bachireddy, Magdalena Thurin, Vincent T. Ho, Wandi Zhang, Sarah Nikiforow, Nicoletta Cieri, Jerome Ritz, Stacey Gabriel, Mariano Severgnini, Aashna Jhaveri, X. Shirley Liu, Haesook T. Kim, Jingxin Fu, Kenneth J. Livak, Sacha Gnjatic, Scott J. Rodig, Alexandra Savell, Philippe Armand, Catherine J. Wu, Teddy Huang, Joseph H. Antin, Corey Cutler, Carrie Cibulskis, Livius Penter, Shuqiang Li, Howard Streicher, Donna Neuberg, Srinika Ranasinghe, Matthew Nazzaro, Yi Zhang, Emily M. Thrash, Helen X. Chen, John Koreth, Seunghee Kim-Schulze
Publikováno v:
Blood
Relapsed myeloid disease after allogeneic stem cell transplantation (HSCT) remains largely incurable. We previously demonstrated the potent activity of immune checkpoint blockade in this clinical setting with ipilimumab or nivolumab. To define the mo
Autor:
Christina M. Tringides, Mariano Severgnini, Waihay J. Wong, Georg N. Duda, Kwasi Adu-Berchie, Kai W. Wucherpfennig, Yutong Liu, Ann Mullally, Olga Pozdnyakova, Kyle H. Vining, Anna E. Marneth, David J. Mooney, Joshua M. Grolman, Alexander G. Stafford
Publikováno v:
Blood. 138:2539-2539
Myelofibrosis (MF) is a progressive, myeloid malignancy characterized by deposition of collagen and reticulin fibers in the bone marrow (BM). Previous studies have shown that monocytosis is associated with poor prognosis in MF, highlighting a potenti
Autor:
Jacqueline S. Garcia, Howard Streicher, Michael K Keng, Robert J. Soiffer, Corey Cutler, Mariano Severgnini, Stephanie Andrews, Eric S. Winer, Matthew S. Davids, Jerome Ritz, Ryan C. Brennick, Yael Flamand, Marlise R. Luskin, Alexandra Savell, Ana Lako, Yohei Arihara, Claire Manuszak, Andreas Kantartzis, Richard Stone, Benjamin Tomlinson, Edwin P. Alyea, Vincent T. Ho, Nicole Cullen, Lillian Werner, Myrna Nahas, Pavan Bachireddy, David P. Steensma, R. Coleman Lindsley, Andrew M. Brunner, Catherine J. Wu, Scott J. Rodig, Martha Wadleigh, Samer K. Khaled, Donna Neuberg, Daniel J. DeAngelo, Ilene Galinsky
Publikováno v:
Blood. 134:2015-2015
Background: Patients (pts) with MDS or AML who relapse after allogeneic transplantation (allo-HCT) have a very poor prognosis. Hypomethylating agents (HMA) and checkpoint blockade with the anti-CTLA4 blocking antibody ipilimumab (IPI) have each induc
Autor:
Amy Simon, Barry L. Fanburg, Brent H. Cochran, Satoe Takahashi, Bathsheeba Andrahbi, Regina M. Day, Mariano Severgnini, Liliana M. Rozo, Abena S. Agyeman
Publikováno v:
Cell Biochemistry and Biophysics. 42:263-276
Serotonin (5-HT) stimulates superoxide release, phosphorylation of p42/p44 mitogen-activated protein kinase (MAPK), and DNA synthesis in bovine pulmonary artery smooth muscle cells. Both p42/p44 MAPK and reactive oxygen species (ROS) generation are r