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pro vyhledávání: '"H Stacey"'
Autor:
Neill H. Stacey, V. Kefalas
Publikováno v:
Toxicology in Vitro. 7:235-240
The use of primary cultures of rat hepatocytes as an experimental model for interactive toxicity studies was evaluated by studying carbon tetrachloride (CCl(4)) and trichloroethylene (TRI). TRI is known to potentiate CCl(4)-induced hepatotoxicity in
Autor:
Neill H. Stacey, C.L. Bai
Publikováno v:
Toxicology in vitro : an international journal published in association with BIBRA. 7(3)
The hepatotoxic effects of chlorinated hydrocarbon solvents have been well recognized for many years. More recently serum bile acids (SBA) have been considered as a sensitive indicator for the determination of liver dysfunction. However, changes in S
Autor:
Vicki Kefalas, Neill H. Stacey
Publikováno v:
Toxicology and applied pharmacology. 109(1)
A number of chemicals are known to potentiate the hepatotoxicity of carbon tetrachloride. The halocarbon trichloroethylene was shown in a previous study to enhance both carbon tetrachloride-induced toxicity and lipid peroxidation in isolated hepatocy
Autor:
Neill H. Stacey
Publikováno v:
Toxicology in Vitro. 3:137-143
Hepatocyte suspensions were exposed to carbon tetrachloride (CT), chloroform (CF) or 1,1,1-trichloroethane (TE) or the various combinations of these three chemicals over a 3-hr incubation period. Enhanced toxicity, as determined by loss of intracellu
Autor:
Neill H. Stacey, Vicki Kefalas
Publikováno v:
Toxicology and applied pharmacology. 101(1)
Hepatocytes isolated from Sprague-Dawley rats were exposed to carbon tetrachloride together with various concentrations of trichloroethylene over a 40-fold range. A potentiation of carbon tetrachloride-induced lipid peroxidation by trichloroethylene