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Autor:
Jiarui Wang, Xianqin Zhang, Tingting Zou, Dazhi Zhang, Wenqiang Liu, Zhenxing Liu, Xuejie Peng, Zhengyi Ni, Yang Tan, Meiqi Hou, Mi Zhou, Chao Yuan, Xiaopei Zhou
Publikováno v:
Biochemical and Biophysical Research Communications. 591:124-129
Mendelian susceptibility to mycobacterial disease (MSMD) is a rare monogenetic disease, which is characterized by susceptibility to some weakly virulent mycobacteria. Here, we explored the pathogenic genes and molecular mechanisms of MSMD patients. W
Publikováno v:
PLoS ONE
PLoS ONE, Vol 11, Iss 3, p e0151184 (2016)
PLoS ONE, Vol 11, Iss 3, p e0151184 (2016)
Aims To isolate and characterise phage which could lyse P. acnes and to formulate the phage into a delivery form for potential application in topical treatment of acne infection. Methods and Results Using standard phage isolation techniques, ten phag
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3d75eed7073471bc6069b36b98ee5822
Publikováno v:
Laboratory Investigation. 102:38-47
Colorectal cancer (CRC) is the third leading cause of cancer-related death worldwide. Dysregulation of circular RNAs (circRNAs) appears to be a critical factor in CRC progression. However, mechanistic studies delineating the role of circRNAs in CRC r
Publikováno v:
Molecular Immunology. 141:1-12
Cryptocaryon irritans, a holotrichous ciliate parasitic protozoan, can trigger marine white spot disease and cause substantial economic losses in mariculture. However, methods of preventing and curing the disease have negatively affect fish, human, o
Autor:
Masa-Aki Ikeda, Khandakar A.S.M. Saadat, Zekiye Altan, Cuneyd Parlayan, Kaifee Arman, Yunus Sahin
Publikováno v:
Biochemical and Biophysical Research Communications. 585:89-95
Osteosarcoma (OS) is the most common primary malignant bone tumor which has unclear pathobiology. Hence, enlightening the exact molecular mechanism underlying osteosarcoma progression is crucial for developing new treatment strategies. One member of
Publikováno v:
Bioengineered
article-version (VoR) Version of Record
Bioengineered, Vol 12, Iss 2, Pp 10959-10970 (2021)
article-version (VoR) Version of Record
Bioengineered, Vol 12, Iss 2, Pp 10959-10970 (2021)
Circular RNAs (CircRNAs) were reported to play vital roles in the progression of DN. Herein, the action of circular RNA_0037128 (circ_0037128) was investigated in DN. The level of circ_0037128, microRNA-497-5p (miR-497-5p) and nuclear factor of activ
Publikováno v:
Molecular Biology Reports
Carson, J, Robinson, M, Ramm, G A & Gobert, G 2021, ' RNA sequencing of LX-2 cells treated with TGF-β1 identifies genes associated with hepatic stellate cell activation ', Molecular Biology Reports . https://doi.org/10.1007/s11033-021-06774-3
Carson, J, Robinson, M, Ramm, G A & Gobert, G 2021, ' RNA sequencing of LX-2 cells treated with TGF-β1 identifies genes associated with hepatic stellate cell activation ', Molecular Biology Reports . https://doi.org/10.1007/s11033-021-06774-3
Background Hepatic stellate cells (HSCs) are liver-resident myofibroblast precursors responsible for the production of collagen and maintenance of the hepatic extracellular matrix (ECM). As such, they are generally associated with fibrotic liver dise
Publikováno v:
Molecular Biology Reports. 48:8155-8170
Nuclear receptors are the regulatory molecules that mediate cellular signals as they interact with specific DNA sequences. NR5A2 is a member of NR5A subfamily having four members (Nr5a1-Nr5a4). NR5A2 shows involvement in diverse biological processes
Publikováno v:
Molecular Biology Reports
Background Human metapneumovirus (hMPV) is one of the important pathogens in infant respiratory tract infection. However, the molecular epidemiology of hMPV among children Methods A nasopharyngeal flocked swab, nasal wash, or nasopharyngeal swab/or o
Autor:
Takatoshi Hikida, Hiroshi Shiraishi, Minoru Fujiki, Takashi Kobayashi, Hiroyuki Fujinami, Ikuko Morisaki, Josef M. Penninger, Toshikatsu Hanada, Reiko Hanada, Nobuyuki Shimizu, Yuji Arai
Publikováno v:
Biochemical and Biophysical Research Communications. 570:60-66
Cleavage factor polyribonucleotide kinase subunit 1 (CLP1), an RNA kinase, plays essential roles in protein complexes involved in the 3'-end formation and polyadenylation of mRNA and the tRNA splicing endonuclease complex, which is involved in precur