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pro vyhledávání: '"Pei, W."'
Autor:
Gregory A. Petsko, Canhui Wang, Jessica Momb, Pei W. Thomas, Dali Liu, Hua Guo, Walter Fast, Dagmar Ringe
Publikováno v:
Biochemistry
The N-acyl- l-homoserine lactone hydrolases (AHL lactonases) have attracted considerable attention because of their ability to quench AHL-mediated quorum-sensing pathways in Gram-negative bacteria and because of their relation to other enzymes in the
Autor:
Jessica Momb, Dagmar Ringe, Pei W. Thomas, Dali Liu, Quyen Q. Hoang, Walter Fast, Gregory A. Petsko
Publikováno v:
Biochemistry. 46:11789-11799
N-Acyl-l-homoserine lactone (AHL) mediated quorum-sensing regulates virulence factor production in a variety of Gram-negative bacteria. Proteins capable of degrading these autoinducers have been called "quorum-quenching" enzymes, can block many quoru