Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Sushanth Gouni"'
Autor:
Misha Hawkins, Nathan Fowler, Sandra B. Horowitz, Sushanth Gouni, Yago Nieto, Christopher R. Flowers, Jason R. Westin, Loretta J. Nastoupil, Raphael E Steiner, Haleigh Mistry, Michael R. Green, Paolo Strati, Luis Fayad, Simrit Parmar, Lei Feng, Swaminathan P. Iyer, Jinsu James, Mansoor Noorani, Sattva S. Neelapu, Sairah Ahmed
Publikováno v:
Blood. 138:1740-1740
Introduction. Suboptimal CAR T-cell stimulation, expansion, and persistence is of theoretical concern in absence of CD19+ tumor B-cells. Adequate CAR T-cell expansion has been reported in the JULIET study among 7 relapsed or refractory (r/r) large B-
Autor:
Allison C. Rosenthal, Madiha Iqbal, Amy Ayers, Manali Kamdar, Brian T. Hess, Lei Feng, Arushi Khurana, Sattva S. Neelapu, Yi Lin, Sushanth Gouni, Reid W. Merryman, Paolo Strati, Andrew Ip, Jennifer L. Crombie, Grace Watson
Publikováno v:
Blood. 138:2495-2495
Introduction. About 60% of patients with large B-cell lymphoma (LBCL) relapse after standard of care (SOC) anti-CD19 autologous chimeric antigen receptor (CAR) T-cell therapy, CD19 downregulation representing a major mechanism of resistance. Therefor