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Autor:
Sheona Watson-Scales, Linda Greensmith, Eva Lana-Elola, Matthew Williamson, Federica La Russa, Victor L. J. Tybulewicz, Bernadett Kalmar, Sara Wells, Emma Nye, Elizabeth M. C. Fisher, Anna Olerinyova, David L.H. Bennett, Heather Cater, Rachele A. Saccon, Amy Slender, Y. Eugene Yu, Radma Mahmood, Dorota Gibbins, Frances K. Wiseman
Publikováno v:
PLoS Genetics
PLoS Genetics, Vol 14, Iss 5, p e1007383 (2018)
PLoS Genetics, Vol 14, Iss 5, p e1007383 (2018)
Down Syndrome (DS) is caused by trisomy of chromosome 21 (Hsa21) and results in a spectrum of phenotypes including learning and memory deficits, and motor dysfunction. It has been hypothesized that an additional copy of a few Hsa21 dosage-sensitive g